Mass screening programs can lead to overdiagnosis, where detecting slow-growing cancers that would never have caused harm results in unnecessary treatments without improving survival outcomes, as demonstrated by Korea's national thyroid ultrasound initiative that caused diagnosis rates to skyrocket while death rates remained unchanged.
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Korea's Thyroid Cancer Initiative BackfiredAdded:
Thyroid is a bit unique in another regard, different from prostate and other cancers. The treatments for metastatic thyroid cancer are quite good. While I don't advise doing nothing, then doing sequential ultrasounds makes sense because if you delay the diagnosis, it's not likely to matter at all. But it's likely to save you a lot of hardship. In Korea, they made it a national initiative to make sure that they got out there and they ultrasound thyroids. We're going to get rid of thyroid cancer. We're going to have a national health initiative. to ultrasound thyroid glands. They did. The rate of thyroid cancer diagnosis, you look at the graph, it's skyrocketed.
Thyroid cancer diagnosis went through the roof. Most of these thyroid cancers are indolent. Taking the thyroid out surgically causes harm without benefit.
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