Gender Affirming Care in Exile: Targeting the Leader

追加: 2026-05-17

[00:00:00]When patients don't respond to clozapine, there's close to no research to guide us, which makes this study by Naveen Hegde and colleagues in the Asian Journal of Psychiatry is a big step forward. Augmentation of clozapine with dextromethorphan in treatment-resistant schizophrenia, a randomized group sequential adaptive design controlled clinical trial.

[00:00:20]Dextromethorphan is familiar as the antidepressant accelerator in Auvelity, but the rationale to use it here comes from a glutamatergic theory of schizophrenia.