Precision Medicine in Asthma | Personalized Treatment Explained | Dr Shivanshu Raj Goyal

追加: 2026-05-24

[00:00:03]Let's talk about the role of >> [music] >> precision in pulmonology.

[00:00:09]Now, >> [music] >> precision in pulmonology has come a long way.

[00:00:13]It you know, varied fields [music] have been covered. But, let's talk about the role of precision treatment in asthma.

[00:00:20][music] We all have been hearing the term asthma. A lot of people know about asthma as a disease where one is uh finding it difficult to breathe.

[00:00:30]>> [music] >> There is wheezing, there is ronchi, and you know, you cough, you bring out phlegm.

[00:00:36]But, now it is the era [music] where you specifically treat a patient of asthma as per the phenotype.

[00:00:43]The patient could be suffering from [music] a disease which is allergic phenotype. There can be asthmas which [music] are non-allergic. There can be various types of asthma which are only linked with having cough. That is called a cough variant asthma.

[00:00:57]There could be an asthma which is just [music] linked to the ingestion of a medicine called aspirin.

[00:01:03]Very commonly called the [music] aspirin-induced asthma. Similarly, there is something called the exercise-induced asthma [music] or a cold-air-induced asthma.

[00:01:12]So, different types of asthmas are there.

[00:01:15]Why all [music] this knowledge is important? Because one medicine does not fit everybody.

[00:01:21]For example, a patient who is having an allergic variety [music] of asthma would be responding to inhalers which contain steroids. They do respond [music] to anti-allergics, specifically anti-histaminics, or even oral steroids. But, people who have a non-allergic [music] variety of asthma or a non-atopic asthma, they would not respond to steroids or anti-allergics. So, if you keep giving them, whether it is a kid or an adult, [music] they would not respond. Rather, it'll be counterproductive.

[00:01:54]A good pulmonologist >> [music] >> would, at the beginning, at the outset would do the phenotyping of your case by doing a lung function test followed by [music] a test called FeNO.

[00:02:06]FeNO is a test which understands the eosinophilic inflammation of [music] your lung.

[00:02:12]In case the FeNO is high, you are thinking more in terms of an allergic variety of asthma rather than a non-allergic asthma.

[00:02:21]Similarly, then there are various other modalities to differentiate [music] this.

[00:02:25]This is called a phenotypic precision-based medicine in pulmonology. [music] What we actually in a layman term would also call it as a personalized treatment.

[00:02:38]Once you do this, you're able to give better results, most importantly [music] with least side effects, and at the end you have a happy patient >> [music] >> with a better outcome.

[00:02:52]>> [music]