This lecture provides a rigorous anatomical framework for understanding neurodevelopmental variance through the lens of early embryology. It effectively bridges the gap between molecular signaling disruptions and clinical neurological outcomes.
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BRAIN SPECTRUM OF COMPLICATIONS.NORMAL EMBRYOLOGY/ Autism and othersAdded:
Yes. Yes. People, welcome to the platform. Today it's on Tuesday, a very chilly day here where I am.
And a very cold day. makes me always have some cup of tea and a warm tea. So today we're going to talk about some spectrum of diseases.
We're going to talk about spectrum of diseases.
We're going to talk about brain complication.
We're going to talk about brain complications and the complications that are brought when a person starts to develop. You get there are some complications that you can start having when you're starting to develop and those ones are the ones that we are going to talk about today.
So everyone everywhere you are, everyone everywhere you are, you are welcome. As I set up some things here check here.
So, um as uh people come in, we want to understand some issues that occur when uh A person is having complications of the brain. You know when there complications of the brain can come from development when you are born or they can manifest when you are an adult because of your own um exposure to some things lifestyle complications and others. Today there are several spectrum of diseases that going to look that is depurually depual. You tell you can tell by the eyes and head shape.
His IQ is mid60s.
What do you mean by that pain? This is we talk here we talk about medical complications, health complications. We talk about health issues. So if you are here, you are new, welcome. Today we are talking about spectrum of diseases from the brain right from uh when you are born to the time you grow up. Spectrum of diseases like schizophrenia, bipolar, there are some others like autism but today we'll do autism. Before we do autism, we will talk about issues about how normal the brain and the a person grows from conception. So, uh if you are here, you are a new person, don't fail to subscribe. Don't fail to ask any question. Don't fail to hit the like button. At least hit the like button as we continue to to study. There are several spectrum of diseases that people and have uh we we last time we talked about schizophrenia and uh you saw how it was it was a bit people wanted to understand how it comes and we learned about the meolyic pathway meotical pathway on is here on welcome.
We only we have a new person called Ten Tain Actual. You can tell by the eyes and the shape of the head. His IQ is mid60s.
So, welcome welcome everyone. As we wait for the others, you can like like like you can hit the like button. You can uh um subscribe if you are new. Welcome Onyx. Welcome to the platform. Welcome to the platform. Everyone that is coming in, welcome to the platform. Here we discuss medical issues. Today's topic is spectrum of diseases that affect us as we grow right from conception. You know right from conception is right from when you are in the mother's womb. So there I let me name some spectrum of diseases that can affect us. We have a autism spectrum of diseases. We have autism. We have schizophrenia. That one we had covered it partially. Bipolar disorders.
We talk about bipolar by the way.
Obsessive compulsive disorders.
Substance abuse disorders. You know substance can interfere with your brain like bang cannabis all those they can interfere with your brain. Any disorders. Anxiety disorder is a very complicated thing.
Sometimes it can effect of the brain.
Depressive disorders. Depressive disorders can be because of some substance. So every new person that you are here, you are free to ask any medical question we discuss and also interact with the people at the chat.
Don't fail to give a like. If you wish, you can always subscribe to the channel.
We talk about medical issues here. So welcome everyone. Welcome to the channel. Today we will talk about uh we'll talk about autistic people. Autism spectrum of disease autism eating disorders, bulimia, binge eating.
You see all those we'll talk about them.
uh personality disorders, personality disorders, fetal alcohol spectrum disorders, intellectual disabilities, chronic kidney disease, h chronic kidney disease, we will talk about those and uh chronic obstructive disorder. So, welcome everyone and um I'm not seeing any like or we are just beginning. So, if you are watching, please hit the like button as we continue. Hit the like button. As we continue, uh, you know, likes sometimes they bring they bring likes bring um impressions. When you give me a like, it's good. You have like it's like you have told someone else we are online.
Please come and check out this and that one is a a good thing. Now those are the things that we're going to talk about it today. So there are some things that we want to discuss about um about how when when a sperm gets to the oam and then how the the egg becomes a baby because if you understand if we understand how a sperm becomes a baby then when we can understand how spectrum of diseases occur like autism that is how we and understand how some things come up and why some things because people will ask you this why can't do they do anything to this person because now you can't do anything because it's a formation process and it's good to understand let's talk about embryology king welcome thanks a lot for being here it's embryology and you know embryology sometimes when cells have fused when have fused it is hard to unfuse them and start again you get so welcome on welcome and everyone who is watching let's continue it is important we note down some facts before we talk about schizophrenia before we talk about autism before we talk about anything else let's talk in an overview how a cell can be how a child fuses and then after it fuses a baby comes in. Now we have this I will put up these structures here. I'll put up some structures that uh people will watch and then we see when when when uh let me get this. When when um a woman and a man uh make love, the sperm goes into into We are we want to understand how some complications come through conception when it is congenital. So I'm drawing and we get a good pen. I want everyone to understand how autism comes. I want everyone to understand how autism comes and how some people are born with complications that are not known. complications that you just get someone as a a a problem and you don't know where this problem came from. You get it is through birth. So welcome everyone. I welcome everyone to the channel and let everyone if you are new just subscribe or give me a like and subscribe or give me a like. It will be enough for a day but stay around and listen to what we are going to talk now.
This is over from a lady. And then this is let me use a red pen, a blue pen. And this is a a sperm. A sperm. Sperm sperm. So when this sperm gets in this, I want everyone to understand how autism comes. When it fuses, it forms 46 chromosome. So this sperm fuses and it becomes like gets like this through some chemical that bust through your your head. So when they fuse they form some layers in your this is the next step. Now the sperm has gotten into the has gotten into the ovary and then they form something like this. You get you get mula. So this thing is called a morula.
A morula. A moru.
A morula. I'm going faster so that you can have some time. So morula is from the third day to the fourth day. It forms something like this. Now the sperm has entered and you formed a morula from the third day. So as we continue as we continue form something that is called a blastoyist formation arrow.
cells. Now the where the cells are are now where we will start talking about this thing.
Let me draw it so that people can understand a blast system. You you you sometimes um wonder what do a sperm and a sperm and how do a sperm and an or form a this is it. Now it has come from a mula and this one is a blastosis. Now this is where problems come when it comes to so this is a blastois. It is called a blastosis.
Blastosis. This is what is called a blastois.
A formation of several cells. I want you to check it clearly. This is the sperm entering and then this is the morula and then we have a a combination of cells.
Now these cells when you start having the the child in a womb that is implanted they start forming it it goes and implants to your uterus. It implants to your uterus. Let me draw a uterus.
Let me draw a uterus. You see it.
Now this is it.
Now this is your uterus. Now it implants to the layers of the uterus and then it starts to to grow. So it is divided into three layers. When it goes into the uterus, it it is divided into three layers. One is called the ectodorm. Let me draw it.
Let me draw it. You see I don't know.
Now you see this we have started from where the sperm is fusing to the ov and then we are at the morula which is the formation of the bone and then the blastosis cell starts to form and then after cell starts to form it is implanted to your uterus. After being implanted to your uterus, you form what?
A bigger cell that has layers. These layers are formed into e ectodom, meodam and endodam inside your uterus.
Ectodorm, meodam. I'm going through this so that people can understand how when I'll start talking about when I'll start talking about um when I start talking about autism we will understand how these things form and they grow you get so they form ectodorm meodm and endodm. So the ectodam forms the neural tube. The ectodam.
The ectodam. The first one forms a tube.
It forms a neural tube. The meodam forms a the meodam forms something that is called a meodam forms a something that is called a forming a a transforming tube. You get a transforming tube. We will see about that. This is just an overview of it is just an overview of um process of formation of a baby you get.
So fetal period starts by week 9. So the neuron tube is the ectom which forms around. So this is how your baby comes and the problems that come in are when people are autistic the problem starts from the neural tube and the blastois.
Today we are talking about autism and how it comes. So it is very to understand how a child let me repeat if you are a new person here today um here we talk about medical issues. So today I'm talking about spectrum of diseases and I've started with autism and before autism it is important people get to know people get to know how a baby is conceived and then how it forms. So this one is a sperm getting into a woman's ov. Then it forms some lines like this one which is called morula. And then it the morula this line turns into cells now which are transferred and are are implanted to the uterus of a baby of of a woman. Uterus of a woman where now they form layers. These cells form layers. Ectodorm, meod endodm and then it forms something that is round. It it is like this. It comes like this. Let take you see this. You see this ovary that has formed a a round thing.
It forms a round thing like this. So the ectodam is the outer part. So it forms a neural tube and gets in like this. So when it gets in you know it was it was electrogram was up but when it forms a neural tube it gets in and then it comes like this. So inside is where now you start forming the the layers of the mouth going down to the stomach up to the anas and then the the other one which is the meodam start forming the hands the legs ears you know and the endodm start forming some measures some organs that is how a baby starts from inside. So if you are new here, you know what we do here. We talk about things that are medical. If you have heard about that and there is something you have not understood, this is just an overview of embryology. How a baby starts to form right from conception. You know after the sperm fuses with the ovary, there must be some things that happen before before now a baby is formed. So we have said let me repeat before I start autism and how the complication began begins. There is a you have made love with your woman the sperm has gone into the cell. It has form a big ball with lines inside called meodm. So it it comes and forms a blastois. The these lines that are formed they form cells a lot of cells inside called a blastosis. So those cells are are implanted into the uterus.
After they implanted, they align themselves now well. They align themselves well and then they form the ectodom, meodam and endodam. They form the ectodam, meodam and endodam. This is where now life begins after those cells have formed because when when now the endodm has formed this where the the folding of the cell and then you start having hands the umbilical cord you start having the ears you get but the endodm is the neuron thing it's the main thing that forms the it comes the neural tube get and then now after It gets in its organs and that is the an overview. It's just an overview of the normal embryology. How the the the cells migrate and then they form a baby. How the cells migrate and then they they form a baby. Now there is something called embryo autism. Let's start with autism. We have learned several spectra diseases and I've showed you how a normal an overview of how a normal thing goes. How a normal embryological process goes here. How a normal embryology it's a very complex it's a very complex uh situation at times but this is the easy way we can talk about it. Okay. Now let's go to what is autism? Uh from the cellular from what we have learned from what we have learned here. From what we have learned here what is autism? Autism is is at the cellular level is complex and it involves abnormalities in the brain development.
Nicholas Journey Extras. Hello Benjamin and everyone in the chat. Nicholas welcome. Today we are talking about pot and I've just said how how um a baby when it a sperm gets into the oven how it is formed into a baby a quick overview. So it is about the brain synaptic function and neural signaling here and when neural neural tube you have seen the first layer which is the ectoduct is which makes the neural tube and there are some pathways that signal it before it start folding and going inside. So this one um during early brain development you know when the ectodor has gone in now those are cells around bone that are implanted into the uterus into the uterus when the ectodor goes in there are some things that happen the neural migration is disrupted this is how autism comes you know when it is sorry When when the baby is when the OA is implanted into your stomach, you have made love with your fashion in love and then it has form a morula and then it is implanting. Now at this step step at this step at this step when the neuron is is forming and getting in when this step it is forming and getting in you get this is where the problems begin.
This is where the problems begin. The when I say the pathophysiology this is where the problems now begin.
The neuron migration is disrupted.
neurons may end up in the wrong cortical layers. You get because if we have seen this is the outer is the neuron and then it is going in. Remember what we are talking about? We are talking about a a blastois that is implanted into the uterus of a woman forming a child and then maybe um when it is getting in when it is getting in when the now the ectodam is folding to get in some things happen to this child maybe genetic. Let me Let me get this because someone may ask that question. So when they are disrupted, remember they are cells and they are going going and that's why women get women get folic acid when they are pregnant and some supplements to make the process go in a good way. So autism starts from conception.
It may start from conception when the child is forming in your in your womb.
You see from that step the neural cells are disrupted as they fold going in to form organs and you know inside is where now this layer that is going inside forming the neural tube. Uh if you are watching not understanding what we are talking about today we are talking about how autism starts how autistic uh complications start and I'm just naming how it starts from how a person is disrupted and then the brain end up having a problem. Now you see when it is forming and going inside if any cell even one cell is disrupted it may end up being left on top or being left somewhere. So the layer that will will form a a brain because you see this hand I'm taking it now like the I'm taking this hand of mine as the the ectom meodam end that is implanted in the uterus. So this one I'm taking it as an hand. I want people to understand this. You see when it is going inside it is forming the layers that are inside this ball are the ones which will form organs and the organs that will be formed they start from the brain nose inside from the you get internal organs. So as they form internal organs the meodam sprouts sprouts and then it forms hands and legs and then there are some things little things that end do you get? So if you are coming in right now there are some we are talking about medical issues here and today we are discussing how autism starts. How autism starts.
So whatever I'm explaining is autism from cellular level from the day a sperm meets an over and then the complication that occurs when the the folding of the layers come and then the child starts to form inside the womb of the mother the uterus itself. So if you are new I can see new people are here watching. If you are new, please hit the like button and let's let's learn. Let's learn. If you are new, hit the like button and let's learn. Don't forget to subscribe. If you have a question, you can ask anyone at the chat or you can ask me directly any medical question. But today we are talking about spectrum of diseases that are born from conception. So what can make these layers? You have understood what can make these layers to do what to be disrupted. Let me form a draw a forming layer so that someone can understand.
Now imagine this is the ball and this is now how it folds.
So any layer that will go inside and fuse inside the ball. So the forming is this you see this was the this was the end ectodam meodam and endodam after they have ecto is outside meodam is inside midway and endodam. Now this one folds in and the other side forms it and then in apart from this downward here is where now you start having forming of organs of a baby. But the process when it is continuing when the process is continuing what happens maybe some things happen. What can cause this ecto layer the forming the neural tube? You know it is a migration of cells. They are the cells that migrate. When they are like this it's not like a ball that is fusing. No it is cells that have many cells. You see how I've drawn here?
There are cells that are many like this one that fuse and start to migrate going in. So when they are going in that is where problems come to we we have genetic issues when a person has this problem. Most affect protein responsible for movement signaling or structural support you get. There are some proteins genetically people have in their genetic makeup that may disrupt the the process of folding. So you find one cell or two cells have been left up and they are messod cells. So they'll f they one cell or two cells. Yes T welcome to the platform. Welcome. Today we are talking about how how autism occurs right from conception. So if you have a question you are really welcome and you are welcome to ask anything. Let's go slowly. Now you see if this is the normal the normal migratory pathway a sperm and ovary it fuses it goes inside then it forms a morula. The morula forms many cells. CJ rehab grand rising. Welcome. Welcome CJ Rehab. Now these cells are many. It forms a ball of cells and that ball of cells is got is what is implanted into Hello CJ.
Welcome, welcome. Today we are talking about we are talking about autism. These cells are the ones go to the uterus. These cells blastosis they go to the uterus and then after they are in the uterus they form a real ball now with layers of cells with the layers of cells. Those layers of cells are the ones which make a baby. Those layers of cells are the ones which now come up with a baby. You see me draw that you know drawing sometimes help people to understand and if you have a question I want people to understand spectrum of diseases by cotism you get autistic spectrum of diseases. Now when these cells are like this the top layer now starts to migrate and it starts to migrate like this these ectodom cells they start to migrate like this. So there are some proteins in a person.
Some proteins in a person there are so many proteins like Lis there is rain abdominal cortical layering BCX conscious and cautical band heteropia.
You see every protein has got what it is aligning as the cells are going in to form now a baby. It is there are cells that migrate. These are cells but remember these cells are in the uterus.
MJ major welcome to the platform. Today we want to understand autism. We want to understand autism. It is not that when you implant this ball of cells which is a blastois it forms layers and then they start to fall. No, there are special cells that are called ectodam, meodam end and and yes ectodor endodam and then these cells now they start forming what the migratory cells that get get inside and then they start forming the layers that you always see come up now with the hand legs with the stomach organs and even with the brain Like let me give an example of a protein that is called relief. Re comes up with abdominal cautical layering the inside from the mouth from the fagus down you see there are proteins that are making diversions to form a baby. Now as they migrate the ectom cells the upper layer cell this one it forms this tube which looks like a tube neural tube. So there are some things that can make that tube to leave some cells up and then you know the tip of the cell the tip down here which comes out with the brain. You see it goes the cells go in and then the first thing that starts is the tip which is the brain. You understand?
That is how a baby comes up. Now, now when the one cell is left out, it means this the brain part will not function as normal. And what are the things that can make one two three cells to be left out or to be disrupted from the way of folding of the human of the human when the the the blastoyst is implanted into the uterus. What if you if you have not understood that process can I repeat guys can I repeat if you are here and you feel I need to repeat I I was starting to to I I was um on I was on autism but for you to understand autism you need to understand embryology how the sperm and the o they fuse and then when they go to the uterus they start forming a You wonder why a ball may just come up with hands, legs, nose, trauma, the brain. You understand? Can I repeat about that process before we go on?
Anyone? Okay, let's continue then. Let's continue. But I can repeat.
This is it. This is it. A sperm. You have made love to a person. sperm gets into the oval it forms a ball called the morula. This morula they start forming cells which align themsel which is the blastosis. So this blastosis it will implant itself to the uterus and then it will form cells of layers like the ectodam, melodam and endodm and then these cells will start to migrate inside the one that a ball imagine a ball that you is going inside itself. So the upper cell which is the ectodam starts to go in. So the inner part is where you start having the layers and organs of your body and there I've said as it is going down as it is going down you see as it is going down to form the layers of your body what happens something may disrupt this tip the ecto leaving some cells up disrupted or destroying some cells and you know the tip may may be the part that will come up with the brain. So there are genetic problems that may bring that people may carry from their genetic line like this which called subcotical band heterotropia in the brain of the of a person. Those are some patterns in the brain. These genes regulate microtubules and cell adations and guidance signal.
the LS1 those protein. So if they are disrupted the signaling of the cells how they migrate may be not normal genetic.
Now just know when if you are in you are born with uh mutation of some proteins like rain DCX and L one it may destroy the fusing. It may jank 47 welcome welcome Jhank it may disrupt the fusing and inner transformation when it is forming the cells are migrating to form the neural tube. So there sometimes a parent may have infections infections may when you are pregnant they may cause those cells to be disrupted. Which cells am I saying? the cells that form the neural tube, the endodm cells. You have a baby, uh you are pregnant the first weeks and then you are at the week the the sixth and the 10th week and it is implantation week and then you get an infection. So there are infections like toxo plasmosis cytogalo virus infection HPV and rubella reubella virus they may affect when the the tube is getting in and it may affect the head how and the the brain. So it this this in intrauterine inflection may cause inflammation. The neural depth the death of the neural tube the neural tube you see we said ectodam comes up with the neural tube which forms the organs of the baby now. So these viruses toxoplasmosis, reubella cytogalo visas may make this neural tube to die and then or part of it of the cells to die and then you may come up with a baby that is not folded well or the brain is not functioning well. Another thing is hypoxia. Hypoxia we say is lack of oxygen, reduced oxygen because maybe the placenta that you has the woman have has a problem because when this thing the mula gets in and then it forms those cells in the uterus of a woman called the blastois.
The blastoes will eject the blastoes when they are implanted. They need oxygen to make energy and to transform into a booby. They the the transforming and the folding needs energy. So when it needs energy and the woman has problems with the placenta, it is called placental insufficiency.
They lack energy to migrate and form the tube that comes and forms the brain. So they may migrate so slowly, they may migrate so slowly and they may get impaired. So if you are wondering what we are talking about my friends, we are talking about how autism starts right from conception. And you have seen autism starts right from conception.
You see when the start when the sperm fuses with the o forms a morula forms cells a ball of cells that are called blastoesis and then they are implanted into they are implanted into the uterus you get if you have a question please don't fail to ask just any question that you failed to I'm kind of like trying to explain in an a language that everyone can understand about how autism starts because we are talking about autistic disorders. So when it gets you it is disrupted maybe by oxygen insufficiency because you remember a childen uh is got from the mother through veins that bypass the liver.
umbilical veins that bypass the liver and they come into the placenta and then this child mother supplies oxygen to the baby through those veins through the umbilical cord. So the mother's blood is supplying through the the child. The child gets nutrients. The child gets and you know when the the child is in the in the womb the lungs are not functioning. So the placenta is the one which when it starts to form supplies oxygen. But at this level the cells are still migrating and starting to form and others want to go up and form the placenta. So disruption by not getting enough oxygen is a crucial thing to this baby. And then we have some things that people do when they are when they are people do when they are pregnant like taking alcohol, drugs like cocaine and exposure to some medic heavy metals like lead and mercury.
You get this may hinder the migration of our ectodam to form ectodam to form the neuron tube that comes up with organs. It may disrupt the normal and the child may come up with autism spectrum because the brain itself has what has a problem? Radiation and nutritional deficiency.
Women when you are pregnant or your friend or anyone who is pregnant please don't fail to take supplement as like fate folate is a very important thing when a woman is pregnant because folate helps to create DNA and you know the DNA is the cells themselves that migrate and form that baby. Flet is the cells themselves. It helps the DNA of it to form. So that as the cells are migrating, you know at that time so many things are happening. The DNA is forming more cells are being multiplied and the mother through the the the meiosis the meiosis. So the mother is kind like needing more more supplements. So folate is the main thing that helps the DNA to so you may not even take the the iron because of reduced but never lack flet in your diet general malnutrition. women that are malnutritionians and they are pregnant no fate in the body no iron and the the the transfer of the electrodam cells are forming the brain endodam sorry and you don't have so the DNA is not being formed as normal you get h abnormal gol function abnormal golon function neuron migrate along radial gill fun fibers Yes.
So this this neuron instead of migrating normally it migrates along red the other side.
So you get the brain that is formed. It is not formed as the normal brain. It may function but it is divided or it is insufficient.
You get? No, we are talking about things that may affect a person so that this person gets into something called get something called autism and then the signaling because you are when they are growing there is something called the signaling pathway. calcium signaling telling cells go this way this way it you know you don't have enough calcium neurotransmitters like GABA in the brain are less and it's genetically you've covered it from genetically so that is those are the some those are things that can make a person to get autism there is something like immune and inflammatory response maternal immunity activation can alter the brain development.
You've seen some mothers when they they go to the hospital, they are given an injection to say to reduce the immunity, not the other one which is called the resource isoimmunization. The one of positive or negative father or negative or negative.
This is when your immunity is fighting against the the implanted into your uterus. Now let's go to autism. Those are the things that um can happen. So there are some things like the synaptic dysfunction when uh when they are forming there are some things that bind. Easily welcome to the platform. There are some things that bind but you find that these synapses don't bind well.
So you find that this this brain is not is not functioning as normal.
Exhibition imbalance.
That one is we have said the neurotransmitters. We always talk about gaba glutamate and glutamate and gaba they help when it comes to transfer of these cells these cells when it is forbing to the neural tube.
You know a body of a person starts from a tube and then inside the tube you get organs outside you get skin and then there is a layer that comes out with uh functional organs and hands and what that is how a person is is formed. So you may get that some things like glutamic activity and reduced GABA inhibition those neurotransmitters in the brain that may make the brain not to develop well abnormal transmitters neurotransmitters when I'm saying neurotransmitters I'm saying about the ones like dopa serotamine elevated in blood of some patients they can injure the migration of the cells and you have said the migration of the cells come out with ectodam ectodam. See this is how things happen from fusing. After fusing you end up having morula cells form the the morula the cells now are implanted to the uterus and then it forms layers. The cells themselves after signaling pathways that were they form the layers and then the layers they get into they get into the cell they now fuse inside. So this ectodom fuses inside to form now organs and then the organs from the meodam and ectodom they form other things like hands, legs you get that this is how a baby is formed. But what I'm saying is this what I'm saying is all this that come out is what forms the doper doper signals these are even you where you are you understand you have something that is dopamine in your brain and um dopamine is the main thing that comes low or overreactive in people that have in people that have Parkinson's disease cerotin when it is elevated in your blood ga those are things that make you reason well and balance your thinking normally they they make you reason well and balance your thinking. So when they are not normal what happens is you start having problems with if you are a woman baby the baby that is inside your your body your your uterus the defective pathway we have some things that are called mitochondria defunction. You see the cells that are maybe in your family you have given birth to no you produce cells one of the father or the mother is producing cells that the mitochondria does not produce energy as needed because the mitochondria we always knew that in a cell it is what is called the powerhouse give you energy through production of ATP so in your family. You don't do what? You don't give out cells that have energy.
They are reduced. They are reduced in energy. They produce reduced energy.
You see? So as you grow and you grow you you start finding that the coming in of the coming in of the cells the coming in of the cell is disrupted. The ecto is disrupted. And what happens when it's disrupted? When it is disrupted what happens? you have a problem of now forming the brain and the other organs. You know, we don't just talk about autism without knowing where it it comes from. H people may say that um it is a genetic thing. It is a a thing that people are born with in family. But now you see several things that are coming out after our discussion are telling us that even a family that does not have autism, you can get autism.
You can get autism through what?
Altered functions. You have seen alcohol.
You have seen stress. When you are stressed up and you are it can it can make your your your pro your you your when you have stress your signaling pathway like serotonin which give you happiness from your brain it can make you not to have the normal transfer of ectodam cells anyone with a question up to there before I continue I can see people are listening slowly and slowly people are listening slowly and slowly.
How did you think autism is?
How did you think autism is?
Let me give a chance before I continue.
I know today's topic is becoming so complicated.
>> If anyone has a question I'm giving a chance to ask, I wanted people to understand. I wanted people to understand how a person gets autism right from conception.
How a person >> right from when the the the sperm gets into the ovary.
Are we are we understanding that process or it is complicated? It seems complicated. Yes. H it starts oism starts right from the day you are sperm gets into the ovary.
Neural tube formation and we have said neural tube formation starts from the endodam the ecto. this one ectoduct it starts from the ecto if we start going deep into this it's a very long process but I've tried to minimize it as per how how things go from the start it's the easiest way you can understand what is and uh let me repeat about it so that when we'll be we as we continue learning about characteristics of autism you may understand and how to diagonize.
You see, let's go again slowly. Let's go again slowly about autism. You see this is the sperm. This is the sperm.
This is the ovary. Over.
So the sperm gets into the oven the tail remains and then after the tail remains you get you get something called the morula.
Now this morula that is here it forms cells many cells that now starts to align themselves around the big ball that is going to be transferred to be planted.
Maybe maybe this morula is somewhere here.
Maybe it is somewhere here coming to be transferred to be trans implanted here.
And then when it is implanted now the cells that have formed to the blasto they start to align themselves like this. Cells that are of ectodam cells that are like morula cells like endodam.
You see? And then the ectodam they start to fold inside. They start to fold inside like here. You get now here from the tip is where you start getting the brain. And we have seen them. That is how a baby forms.
Fac is saying great topic. I started about different types of disorders when I was doing my level seven psychology.
after my son was diagonized with level one of autism spectral disease. Okay, you see you at least now FC you understand where it starts from. You understand it starts from the inside disruptions of cells that are migrating and going inside the cell. You get now let's check it out. How can we diagonize this? We we have seen how the normal cells are done. But now we want to know how we can diagonalize what we can diagonalize the the complication. How can diagonalize the complication itself? How autism is diagonalized? How is it diagonalized? We developmental screen h first steps when because now you cannot diagnize it when the child is growing because when you are doing everything that you are doing you'll find the child is growing well the heartbeat is okay and you never know about the formation of the brain but the growing of the baby inside because the ecto has formed the meod has formed the organs the child is growing it It is done in the early childhood. It is done in the early childhood often 18 to 24 months when the child is born.
We look at when you look at the child no eye contacts. You know we talked about cranial nerves. Nerves that come from your brain. You get the cranial nerves that come from your brain are the one which innovate everything that happens around your eyes and down from the vagus nerve that goes to the stomach.
Now we have optic ulactory. Alfactory is a nerve that comes from your brain that controls your the olfactory smelling. Optic the one it's a nerve that comes from your brain that controls how you see alactor optic oi motor that moves eyes.
You get the muscles of the eyes.
Optical motor tlear again helps with some things that moves the eyes.
Trigeminina.
Uh thank you doctor. The refresher class is appreciated. Welcome, welcome, welcome. We want to understand I'm going slowly because we want to understand about because people talk about autism and they don't understand really what where is it a disease or is it a complication or is it a what you see you see so when the when everything has formed you see like this. When it is disrupted and you see this thing is inside the uterus, it will continue forming. But you remember one cell or two have been disrupted but it will continue forming.
When it is continuing to form, what will happen?
Some of the cells that come up with the cranial nerves, cranial nerves come from the brain and they drop like this and they go to where they are supposed to innovate. So the nerves are controlled from the brain. But you remember our brain had an injury. So if our brain had an injury somewhere, what do you think happened? It injured some nerves. So let me go through the cranial nerves there are 12 so that we understand how autism how autism is classified and I've said you cannot classify autism before the child is born because as you take you go toc clinic we call it antal clinic the child is growing well the heartbeat is okay it's growing so after conception is where you come and realize there are some things that are not adding up. But you see those are micro things started from the cell when the cell was forming the brain. H when you and your husband made love with your boyfriend maybe the the signaling potent that your boyfriend had in their families they were not doing well. the signaling telling these endodam cells now go inside now migrate to the left now migrate to the right have a pro problem with that proteins those proteins have named and another thing you may find some people in their family they are born with you know these are cells and inside the cells we have mitochondria that gives energy. So the mitochondria that give energy some people are born with maybe the sperm cell or really passing through. Good morning everyone morning really. So you may find that some people are born with their sperms or the mothers with with their ovaries that are producing cells that are not giving enough energy for the process to go on well. That is another thing. The third thing is lifestyle. alcohol, drugs, you are taking drugs and they disrupt the process. You see, so as the process is being disrupted or forming the baby, some cells go where they are not supposed to to be. You see, and that's where we come. If the brain is forming and the nerves that help us to do some things and be cautious are coming from the brain.
You get the nerves come from the brain.
What do you think? Some people will not have innovation. It depends with where the problem is. That's why it is categorized in levels.
It dispense with it depends with when the ectodorm was forming the neural tube so that it can go inside and start forming organs.
Which cells were disrupted? Which cells were not going at the right place. Now if you are affected at the end you of you know when the we start from here. So here or end of the brain where it starts from the brain looks like this. So here in the front where we have the olfactory the first cranial nerve cranial nerve only means nerves of the they only mean nerves of the brain. So it starts from the nerve of the brain here. Maybe the one of the cell that was migratory was disrupted and it was coming here. Now you find that child cannot even have smell. It is called olfactory. Alfactory is a nerve that helps smelling. You find that child cannot smell. Optic for vision next to the to the the cell you know the brain here or factory we have another one called the optic. So the optic the the the the nerve comes and it joins something called the optic cayasma to to hear to the eyes so that you can vision you can see well. So if that cell was disrupted at where the nerves of the vision comes from you will have problems with innovation of high and just immediately after the of optic we have something called oculi mode. Oculo motor here as you see we have eye movement. We have eye movement. So the eye movement may be affected with the maybe when the neural tube was being formed and the cells were going where the the nerve of the eye movement was and it was disrupted and left on top.
So you don't have strength and that's why some autistic children you will see some eyes are like this or like this because the nerve that is called the ocular motor oculoto the cells were disrupted.
So that nerve was not complete. So I has gone this side because maybe that nerve is not innovating one side. And then we have tleia, superior oblique, oculum.
From the three after all factor they arise from around the same place of the brain.
Optic, oculomoto and tleia. Optic ocumoto and tleia they arise from the same place around the same place because they are innovating the the eye like the oculum eye movement and pupils the pupil constriction when you are in a dark place they become big. You have ever seen a cat. When a cat is in a you you you it goes into a place with light the eye becomes big.
When it or when it goes to a place that is dark eye constricts it's the work in human it is the work of oculo. So the three nerves oculamoto tleia and tigen they arise around the same plane. Tri try tlear tlear comes from somewhere here.
So it helps oblique muscle. It makes your muscle not to go inside like this.
It makes your muscle to to look straight. That is tlear. Trigeminina facial sensation and chewy.
Now you have seen some children that are autistic.
cheering is a problem.
Chewing is a problem. Or you'll find they kind of are like this. Why? Because there is a um nerve number five which is called trigemina. It comes and it divides into itself into three. It comes and innovates the mandible. It comes and comes to the eye of and it comes to the facial here.
So here the face sensation of the face here is innovated by trigemina facial sensation. That's why when you catch you touch yourself here you can feel here and then the mandible you can chew.
you've met some children that are autistic and they can't chew or eating is a problem. It's because the when the ectodorm was transforming when the ectodorm was transforming maybe the disruption occurred happened where the trigeminal nerve was.
You see maybe it happened where the trigeminal nerve was and it got disrupted.
If you caused a problem with facial sensation or this child eating or this child eating. You see, you see how the characteristic of a of an autistic child is graded just through this. Let's go to number six. AB abduence.
Abduence is eye movement.
We're still in eye movement. So number optic oculoto tleia 3 plus abduses number six both they control eye movement lateral letters it makes your eye not to go up or to go down lateral.
So it makes your eyes to be straight as oblique is pushing this it is making this to push this and your eye to be straight to look straight.
So some eyes of the some are looking down or are looking inside depends with where it depends with where you have a problem. You get now let's go to Hilda Taylor Dr. Benjamin blessings to you and everyone in the welcome welcome Hilda. Now there is another called the stimulia.
Now all these things I'm talking about I'm talking about the disruption you know as they migrate as these cells are migrating to form the neural tube inside and they are disrupted when these cells that are in the uterus of this board are migrating to form inside. It depends with where my son had speech delay. He started speaking full sentence at the age of six. You see, let me continue about the the the the cranial now and you will know why we are at vestibular coia. You have seen some children that are autistic. They can't walk well. delayed milestone and balancing because one the migratory cells of the migratory cells maybe it was genetic or infection or alcohol intake of drugs or something genetic that disrupted these cells and it disrupted the cells that were going to make an area where vestibular nerve that comes from the brain will serve the ears you So this is case that called a autism authorism.
It is called autistic. Autistic really autistic. Now they are here help in balance. Your ears helps in they help in doing what your ears help in balance and they they help in Hello. It's welcome to the platform.
Your ears help in balance and they help in hearing. So the vestibular coccleia cranial nerve number eight is what is responsible for that. So your autistic child may not have good balance. Glossopherial tongues and tongue and swallowing.
Number nine, veers control organs like the heart, lung and digestion.
Accessory, shoulder and movement, hypoglossal, tongue movement. Those are the 12 cranial nerves. So can I repeat my people so that we understand. I think everyone am I clear?
At least I'm driving a point home.
At least I'm driving a point home.
In simple terms, we have 12 cranial nerves that arise from your head. 12 comms that come from your head and they help you to do some things like we have said smell, vision, eye movement, eye movements like chocolate and dimeina, facial sensation, abduence, eye movement. You get all those like vestibular coleia, hearing and balance.
Hearing and balance.
A human being has 12 cranial nerves. And when it comes to autism, 12 cranial nerves. And when it comes to autism, this is where it starts.
When your your your sperm has gone to the ovary, it has formed a morula.
A morula is a ball, a round ball. It then after 2 3 days, it forms something called a blastois, a mass of cells that are implanted into the uterus. When they are implanted to the uterus, they start to to to separate forming layers. The upper one is called the ectodam.
This one is called the meod dump. And then this one is called the endodam.
So what happen is after 2 weeks the extra dam they start to migrate inside the ball like this. So the inside part is what forms the organs and this process of migrating forming this tube that is called the neural tube. the process of migrating forming the neural tube.
If you are listening here, we talk about medical issues. If you are new, check if you have liked and asked a question. If you are not understanding, just check if you have liked and you have not understanding, please ask a question. So when it is migrating now, autism starts from here. This you see here, this is where starts because as the ectodam gets in to form something called the neural tube that comes out with organs like the brain, what the spinal cord this inside here, some things disrupt that process and you know there are cells that can move. So something like nutrition you have not been taking good care of yourself nutritionally folic acid can cause you to have poor migration inside and when you have poor migration inside what happens you start having problems and where the cell was disrupted is where you get a complication and I've said it clearly your brain have 12 cranial nerve and you have seen let me repeat cranial nerve number one or factory starts from the front innovation of smell that's why when you you are hit here sometimes you lose sensation of smell number two is optic vision it helps vision you to see optic diasma oculo eye movement tleia Still eye movement, superior oblique the muscles trigeminal facial sensation and chewing because it's divided into opthalmic opalic optic and mandibular opthalmic facial and mandibular. So when trigenina comes and reaches here it divides into I facial and mandibular. So the one that comes here, it's a nerve that it's divided like this.
So this one helps your nerve to come up as you chew. Some children don't know how to chew. Autistic children that is trigeminina, eye movement, facial facial expression, anterior tongue. So facial there is a nerve that is called facial nerve number seven when it comes it comes up to somewhere here that is called the contacted bunny and then it helps the n from here to two of the tongue it you can feel taste >> you see and then facial expression when you smile is the one which gives you a smile makes you feel down the facial expression.
Vestibular coia is the number eight.
Number eight balance glossoparangial the tongue posterior tongue from the you know facial was serving the ear to a third.
So glossopharangial move the tongue and serves from the third that is remaining and swallowing.
It helps you even to swallow that nerve.
Vega nerve things like the heart. When we talking about the heart, you saw it was doing something about parasympathetic system. Parasympathetic system, lungs and digestion.
The vagus nerve, it was called the vagus nerve. Why? Because it comes helps the brain, the heart and goes up to the stomach. It is everywhere.
Number n. Number nine. Uh that is number 10. Number 11 is accessory which makes you brush your shoulders.
Number 12 is hypoglossal tongue movement. Now according to what I've said if anything on the brain was disrupted somewhere where these nerves are coming from is how you depict a child's problem is where you pick where your child's problem is. And it comes with the grading. You see the development and diagnosis of a autistic child comes from where? Anyway before I go to how it is diagonalized. I know people are listening so kindly. Can anyone have any question from where we started? How your cells are merging? How how what do you tell me what do people say about the autism?
What do people say about autism?
About what you know autism? How do people speak out about autism? Like Ephas said her son was diagnized with uh with autism. What did you think it was at that moment? What did you think it was?
Level one. It was level one. Yes. Yes.
She said level one. But I've I've seen several people talking about uh several things about genetics myths that are there. You know the myths that are there and even some people don't understand how autism itself begin.
Now you understand it starts from the neural development when the tube that forms the hand the legs the comes out.
You get anyone with a question up to there before we move on. You know a session that is interactive is good when you listen so much and you don't ask question. I know you have a lot of question.
Let me listen to a one question or two before we continue.
>> Let me get one or two before we continue to to diagnosis.
>> Anyone with any question?
You know it's good to understand even sometimes the diagnosis itself sometimes diagnosis of autism it it's a complication to some medics even to some doctors because now you can confuse autism with some greetings to you all and everyone in the house levels are many there. It can go up to seven. Let me get I can see Jamaican uncle in the house. I find it very interesting the way how the body function at how now you you understand uh really your body started as cells and now and the cells that are migrating going inside and then they come out.
Now M has asked a question how much levels are there? The normal ones that people know are three.
The the normal ones are three requiring support which is M level one that FC has told us require substantial support moderate and requiring very substantial support severe but we will see of other levels but for now just know there are three. Uh >> it's okay.
>> I think Ridley is is getting Ridley is surprised on how >> levels occur. Welcome Jamaican uncle. We have been discussing about how autism starts from conception from when you conceive to the time the baby is born. So the diagnosis always comes after Monday. I hope I've answered your question. For now, let's know about the three normal levels. But as we talk and talk and talk, I'll I'll introduce some levels.
Now uh it is a a complicated thing because you know when a cell is disrupted at this point of growth in the uterus when a baby is growing you cannot know but it can create a very complicated thing in future and it depends with the neural tube where it was disrupted. You see if it was disrupted at any level of the 12th cranial nerve is what depressed outside and how much of the toxin or disruption was there that is what it it depends how much of disruption and how much of you get I don't know if I'm driving the points home because someone that has used cocaine and has convers and is a woman having a can cause a huge disruption.
>> A person that has a genetic problem of concept of when the the over and the and the sperm are fusing, you know, let's say this is a this is a sperm. When it fuses and then the tail is left, you may find that they fuse and then they form a big ball of cells. So you have seen something like mitochondria mitochondria my lucky image. So it slows down the process and the cell of the cells die. So it depends with how the problem started >> and it is diagnized after the baby is born because you will start seeing I know a woman who is bipolar have two daughters both of them autism. Yes.
It is you know even bipolar is in when I started let me start again because I can see we have said that brain complications are made and I said we have this listen we have autism we have schizophrenia bipolar spect obsessive compulsive and related disorders substance and use disorder, anxiety disorders, attention deficit, hyperactive disorder, eating disorders, personality disorders, personality disorders. I learned that mother's age can also be a contributive factor to have an autistic child. Yes, it can.
Ephas, we have personality disorder and we have the ones that are coming from neurological development spectrum, the brain.
fatal fatal alcohol, alcohol take, intellectual disability, medical and chronic kidney disease, chronic obsess and even co virus. So fascia has said so if most probability of people that are bipolar and are women. Welcome coffee cakes. Welcome to the platform. We are talking about how autism starts right from conception.
Mothers that are bipolar, you know, it is a fusion. We will talk about bipolar, you will see it is the same thing.
The progression of cells in your brain that were disrupted during migration.
Let me repeat this. You see, this is a normal chart how a baby is born. I'm repeating because I want people to understand a normal one. You get in this way. The sperm gets into the oven.
It forms a ball that is a morula. And then this morula forms many cells, a ball of cells that migrate after 3 to 5 days, 6 days. They are implanted into they are implanted into the uterus. And then when they implanted with the uterus they forms layers and these layers are called ectodom meodam and endodm ectodom meodam and endodam. So when they form ectodom meodam and endodam >> after 14 days now the ectodam is signaled by specific proteins now start migrating. The cells start to migrate inside like this forming something that is called the neuron tube forming something. You see how they migrate like this. So inside whatever that is going to the tip it is what will start to the brain forming the spinal cord and inside the mouth and then the other layers will form the hands the gastric layers and also you get that is how a baby starts to form. So when the the the ectodam is migrating the cells are ectodom cells are migrating and you are taking alcohol and you are pregnant they may disrupt the movement and some cells may not get inside and the brain function may be interrupted though when the heart beats too fast what can cause it the person not walking fast or running they sit down and they start to beat fast Okay, I'll answer that. So, we have said there are some things that can make a person to have these problems. One is genetics, the signaling proteins are not working well. Two, mitochondria, the energy pathway, the ATP production for the cells to move fast. Maybe in the mother's side or the father's side, they don't work correctly. the signaling the the energy.
You get drugs and alcohol, oxygen, the kidney issues, infections like virus, toxoplasmosis virus, those are things that can cause the signaling. Anxiety, anxiety, we will talk about it. Coffee, you have just started with how the normal uh fat they start all of these are from the brain. So what I'm explaining is the normal but I'm saying the the the crucial part where anxiety disorder bipolar disorders starts from this the fusioning of this going inside so that they can form something that is called the neural tube which comes with your stomach your brain your hands your legs you get this is where autism comes from this is where bipolar starts from This is from where the anxiety disorders comes from. Everything starts at day 141 16. That's why it is important when your women are pregnant please take them give them folic acid to make these cells DNA to grow well and healthy. So N the cofficate pathways that is where the problem starts from in the Taylor I will answer your your question but you know when your heart is beating faster what is it called? It is called palpitations and palpitations can be caused by anxiety disorders.
It can be caused by something that is provocative like hypertension.
It can be caused by it can be caused by something that is external like fear or panic. Can they take folic acid before pregnancy? Yes.
Even human you can take folic acid. For men always take zinc. Yes. Anxiety tachicardia and slow one low dehydration very many thing nicotine and smoking can cause all these fever fever cause palpitations that is for Hilda Taylor fear and panic there are some things that are genetic like anemia hypothyroidism low blood sugar heart rhythm problems arhythmias we talked about arhythmias heart problems, infections and erect electrolyte imbalance. So it depends with what is causing.
So we have seen all those and uh it is very important. Cute Jesse, hello.
Welcome Jesse. Um okay, next week your request will come next week. I've seen you and I've told you. um uh uh your request will come next week. We are reviewing some things.
So no worries, no worries. So those are the problems that we encounter and how starts.
So folic acid is important for women and zinc and magnesium is important for men sperms.
If it is not genetic whereby you have some insufficiencies of some proteins, insufficiencies of some proteins that you should have to signal, you can bring autism to your sons or girls because lifestyle, alcohol, drugs, not eating well, not going for supplements when you are pregnant at an early stage can give your children autism you get. So yes doc I understand thanks.
So that is how autism start and that is how autism.
So as for where you have come and can I get some people tell me how did you think autism started? How or if you have like efficacy, did your doctor um explain to you how they started?
Because you know you cannot have a disease without where it starts from because so many people when you ask them what is autism they tell you it is a disease of the brain.
It is a disease of the brain. Anyone who is coming in and you are confused about whatever I'm talking just ask just ask.
It's time for questions. I think it is important that at least I answer some questions so that next time we do the diagnosis and staging and uh it's good to go slowly. you know, we have seen uh some some of us in the group that has have come out clearly and have said I'm autistic.
My son is autistic. I'm autistic mother I'm taking care. So it means that if in a small group like us the why we are talking there are some that are have autistic it means that autism is there widely and people should understand the need and how to to stay away from these complications because now if you know in your genetic line you have autism someone has autism and you are pregnant you will start taking caution immediately because if you have problems with the signaling pathway, it means from the beginning of your conception when the blastosis is getting into blastosis is the layer of cells that are thick that are being implanted to the uterus so that they can grow. It means you start taking important supplements that will boost.
Yes, tea tea is back. Tea is back. that will boost the cells to have energy the cells not to delay in forming of the neural tube so that the brain of that child can grow well. You have seen autism starts from when the cell imagine at 14 weeks at the first weeks at 14 15 weeks you have started having autism.
Imagine at 14 15 weeks you started having autism. All along you'll be you will not know but you'll come and realize that you have an autistic child at at birth and it's not 14 to 15. Yes. 14 to 15 weeks. You see let me repeat. You see t T yes Sh is here. Welcome Sha. We are talking about how autism starts.
Let me repeat this is my schematic drawing that talks about these things.
This is the ovary. This is the sperm. It is getting into the ovary.
That is the first day of making love.
After you've made love, what happens?
3 to 5 days at the fallopian tube. The fallopian tubes are of making babies making love tea, making love, having sex. So when you've had sex and these are fused, this is the fallopian tube.
They migrate for how many days? For 6 days. After they migrate for 6 days, they are the the the morula that is formed at the first four to 5 days, it forms into a blastois into five to 10 days.
After the 10th day when it is being implanted here 7 to 10 days it is being implanted. After implantation it forms what the cells now at the 14 weeks forms this they put in a layer that forms ectodam meodam and endodm and now this is where autism starts the disruption the disruption of this endodm layer coming this is how they go you see this look at this and Then think of a ball. So at the the endodm starts to go in like this.
You see it starts to go in and inside this round thing is what we call the neural tube. It is called the neural tube. So when it forming the neural tube, the cells that are at the tip, they start forming organs like the brain, the spinal cord and then it forms the the meodm which is this one forms other things like the stomach and else and this one endodm forms the hands and other layers. So this is where autism starts and we have said as it is getting in the cells there are cells they are not aligned they must go well inside every cell that is an ectodorm must go inside but you get that maybe genetically you are born with cells that have no energy because their mitochondria are weak. You are born that with cells that have problems with some signaling proteins because that the for after the 14th day it they must be signaled they must I have named before that starts to make the like the prick and and the others that starts to signal now start going inside but they are mutated they can't signal so the process goes slow some cells are left behind and you No, you cannot if it these cells are for ectodam. They are for ectodom. These cells are for me.
Welcome, welcome, sh. No worries. No worries. I know you are at work. No worries. If these cells are for ectodom, they should be of ectodom. If these cells were aligned for me, they should be of meodam. And if these cells were aligned for endodam, they should be of endodm because they are going to f organs like hands. Meodam they are going to form organs like the stomach everything you get intestine ectodam they are coming to give you the brain and the so they should go as per needed they should not be delaying you get so that is this is a crucial that's why we say immediately a woman is con has conceived after 2 weeks to 1 month you should start the folic acid supplementation But if you know you have a problem in your family of genetic problem like autism, bipolar, go to the hospital, start supplementation very early because that process at 14 weeks to 1 month is crucial. You need energy.
Nutrition can damage it can make the the cells that have no good nutrition to come up with an autistic child. And we have seen the most important thing that we have seen here is your brain has cranial nerves 12 cranial nerves and we have gone through the 12 cranial nerves.
Opthalmic uh olfactory optic oculi motor for smell optic for eye for eye vision.
Oculi motor for muscles of the eye.
Tleia muscles of the eye. Trimina for chewing and facial movement. You get trigeminal. And then we have seen abduence facial. You get abduence facial.
You get facial.
And then we have facial itself facial expression those are if one nerve that arises from the brain there are 12 is injured that is how your child will display problems with eating maybe the place that the brain was developing where the trigeminal nerve is and I've said trigeminal nerve when it comes Here it divides into three. It goes to the multiple optic kulam motor. It goes up to it helps you to chew. So it depends which nerve which cell was disrupted and where was it going?
Benjamin but some are getting autism after injection. What causes that?
After injections, which injections and at what age?
We cannot you know autism is a spectrum of disease that is characterized by age and the disruption and how let me let me get to you know um after you get an injection and then you start depicting some issues it means it went and destroyed your brain cells.
You cannot say that is opi or or you cannot say that that is autism.
You can get autism from 3 to 8 weeks, 8 to 16 weeks. And you see this is in when the conception has happened. neural migration misplace sen formation. This is 20 weeks after birth.
So I I would like to tell cute um that one is a complication that we have a name of of encphylanopathy.
You cannot name that as autism because in uh it you you were born well and uh during after birth after birth you got an injection and it brought a brain dysfunction.
In real life you cannot call that obs we have you can call it enphalopathy like you are injected and then you get convulsions.
You have a an injection the drug IV injection the drug goes to your liver it forms high billubin it goes to your brain you get a child get something called kiceras that is not that is not autism we will differentiate these problems I've said autism comes right from and we will see how they come if you came up early. You you I I I I said there is autism development during gestation where we have early brain formation 3 to 8 weeks and then there is neural formation the tube itself here the tube itself 8 to 16 weeks you get and then we have neural migration 12 to 24 weeks where now the neural is migrating forming now the organ misplaced neurons forming organs that are not normal. Celapse formation forming start from connection the synapse week 20.
You see that is that baby is still in the stomach.
Now that is how a simple way I can explain how um how autism can start.
I I think uh if anyone has any question you can ask because if I start going to diagnosis after birth it can bring several it will take some time Kenyan time cute Jess will have will be having a live at Jesse what time have you said I'm not seeing it uh let me see Jessie repeat I'm not seeing your text what time will you be having that live.
I'll be in five more years before I make babies.
T you'll be in five more years before you make babies. Okay. Okay. Okay. But it's it's good you you start knowing these things early. When you get there, you start going to NC clinics at an early at an early stage. you you don't go to an NC clinic at late stages.
Now this disorder can be managed because it is neural formation and cells that are displayed. Greetings to everyone here supporting. Yes, ever blessed welcome to the platform.
What time have you said? I'm not seeing that text of yours. Please retext it again. I'm trying to find the time that will be online and I'm not seeing what time will you be there. I'm I'm looking so disorder can be cured you know cure there is management Jess I'm I am not seeing oh 23 p.m. that is at night at night. Okay. Okay. The J will be uh at 11:00 p.m.
tomorrow at night. So, please um check her out with her content. I've seen I've seen but that is African time. African time tomorrow. So, let's uh let's get to see that what can make a person have autism. What can make a person start having these problems as the neural tube is forming?
What can make a person have this complication when the neural tube is forming? We have said infection like cytogallo virus reubella reubella can cause viruses can cause I said I'll have a premier tomorrow Benjamin. Yes, I was looking for time. I've seen it. Cute.
QT J there are some immunity issues.
Immunity issues like high cytoines interfere with neuron migration. Cytoines are in >> reconstitute.
Now cytoines are mediators of inflammation.
So maybe you have a disease that is chronic and it is continuing. a disease that is chronic. So when you have that disease what happens you find that it is attacking the it is attacking the cell the blastosis. So when the formation starts it starts interfering with the cells hypoxia placental problems your placenta formation as a problem and the cells are not getting enough oxygen nutritional factors factors nutrition.
So women when we say stop alcohol when you are pregnant mostly when you are at an early stage it is very important alcohol are disruptors of cell migration you get fetal alcohol spectrum disorders fetal alcohol spectrum disorders drugs and heavy metals are problems. So when a doctor says women please stop taking alcohol and you say I've never had a problem you carry the baby going to see you told the baby is okay growing on well the kids are okay and then you you give birth to a baby with and you know alcohol at times suppresses some nutrients like folate iron you understand so when folate is struggling to help you make the DNA of the cells of your baby.
What is happening behind the cut and you're taking alcohol and it's diminishing the the the nutrients that are supposed to you are supposed to be having.
It's very sad. Smoking, you know, smoking has free radicals and it destroys the cell hormonal and metabolic factors, mothers with diabetes, thyroid disorders. You are supposed to be visiting ANC clinics each and every 2 weeks when you have conceived for the safety of your baby.
So that you be checking yourself. Some of you have gadgets that are diabetic at home. Very important.
You see, so gen from genetics to lifestyle, from lifestyle to disorders that are metabolic that we live with.
This is how things are. You get this is how things are when it comes to these problems.
So I I I asked one day a person that what do you think uh what do you think the problem is when it comes to autistic disorders in your community?
And I was told that one that one is a problem that is given by your community or a curse or it's a problem of the brain. When my child was born, the the the doctors, the nurses, they usually say nurses, the nurses did something bad. They they they didn't handle my my baby well. That's why he has and that's why you see some people that are taking these things to court. And the courts when it comes to medical problems it takes that problem to the boards medical boards because they are the doctors. Now the doctors looks at the case and they know there is no medical worker that had a problem here.
This one started from so when it is dismissed you start saying hearing people saying they they really do I'm sorry I have to go you I'll take care of you tomorrow it's okay really we are just about to finish have a blessed day I know you you are working you see these are the factors that some cases are dismissed and that is what at least today I I think people you have understood where autism comes from but tomorrow we'll continue if I start the diagnosis right now it will be it will be so it's a big topic like just the introduction has taken us all 2 hours imagine if we we start the diagnosis now h so who has a question who has a question uh anyone who has a question please post your question as I I'm going to put a line. It will take me seconds before I I I I'll be back. So, post your question. I'll be here in a second. And um and I when there is early intervention, there is such improvement in child social life. The emotions it Yes. When there is early intervention, that is very true.
I'm coming. Just a minute.
What I am?
Thank you.
Nice.
Yes. Yes. Yes. I'm back. I'm back. Any question? Anyone who had a question before we finish it? I have 10 minutes.
10 minutes. Yes. Easy. When it is taken intervention at an early age, you know, at an early age, when a child is born, some cells are still forming. And when it is taken intervention at an early age those cells starts to migrate back to where they are supposed to be or some brain starts to form. We will see about the early age intervention after the diagnosis.
So who wants to understand anything?
Thank you for this. It's so informative.
Yes, m it's so informative. you know when it comes I I decided this because I saw do every like 10 people that we have here one was saying that look I didn't know that autism begins in the brain I've learned something today yes and please uh share share something I I wish Johnny Big Wood was here I really wanted although I've not found her him on phone I I I will someone to share this to Johnny be good. Uh we see how things will go and you have seen for yourself several people we talked to are saying like three from 10 you see one saying I have an autistic child I have this child who is autistic from 10. So it means out there when we inform people you know when we inform people early even not before uh giving birth when we inform people to take measures earlier when you have just noticed that in your family you have a genetic line of autism we can save that greetings greetings rich welcome welcome although we are about to end but it's okay we are talking about autism You know you can save that child not to become autistic when you have just conceived you have gone you know women when you have menes have not come to normal and you go to to a hospital you get the dipst stick you notice ah it's something is not okay you get uh you and you remember that in our line there is this problem. It's very important to run to the hospital.
It's very important to run to the hospital. There are some measures that can be taken so that the migration of the ectodam cells to forming the neural tube cells can be okay by giving you some drugs, some supplements to avoid your child being autistic.
But you know it's very complicated at times and until you realize when this child has been born then you start therapies and you know some therapies are are really complicated.
So if you are coming in and watching now here we talk about medical issues. I thank everyone that has come in. I thank everyone that has come in and everyone who watching rush to catch up but I watch you are like you are like like a Netflix to me rich no thanks thanks thanks I was explaining about autism and people are like you see is saying I didn't know autism begins in the brain I have learned something today yes and it begins right from the day you you conceive. You see?
So guys, thank you for tuning in. Or is there anyone who has a question? Anyone?
Anyone who has a question.
Uh thank you for tuning in. At least you have learned something today which is so important that people can learn can learn and know. So we will I can come at at the normal time at after 2 3 hours. Uh that will be at that will be at let me say uh this is 7 8 9 after 2 hours and a half. After 2 hours and a half I can be online to answer some questions. Thanks. Thanks Rich Poo. I will be calling you Sue. Sue is easy. I can come after 2 hours to answer some questions and then we we we have we continue with the topic tomorrow. We can continue with the topic tomorrow. So the topic we continue with tomorrow will be the diagnosis of autism. Today I've given you Thanks doctor. This is very informative. We are learning a lot. Yes. I've beun with how the normal cells begin they you get implanting and I've seen today people have learned how a child is formed how cells go in then the top layer begins with producing hands one day I'll go through that process step by step so that you can know how the child a child comes out in the stomach and forms it's a very it's a very vast process but this one is just This one is just a an overview, not a very deep step, an overview.
So guys, everywhere you are, if I'll have time, I'll come at 9:00.
You can share this information to a person you love, a person you need. Have a good day wherever you are. Good morning.
You call me Sue. Yes, Sue. I'll be calling you Sue. So is easy.
Everyone who has tuned in, who has liked and uh who will rewatch, thank you so much. Let's meet at 9 for answering questions. If you have a question, you'll be you can tune in. But tomorrow we'll continue with how to diagonize a child has autism and the staging that MJ has.
I will tell you about my nephew who have autism tomorrow. It's okay. It's okay.
Thank you, M for that. So, everyone have a nice day. Let's meet tomorrow at continuing with diagnosis.
And at night, I'll be here answering random questions. I usually answer random questions at about 45 minutes to 1 hour, 2 hours from now. Bye-bye. See you.
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