Neurocognitive Peptides & Brain Health

Added: 2026-05-14

[00:00:00]Welcome everyone. Welcome to LMD's live educational series. We're so excited to have you here today at LMD. We're committed to educating our community and empowering you all with the knowledge to build a healthier future. And tonight is all about learning together and discovering what it takes to live with clarity, vitality, and resilience. I'm Lauren Nasher. I am the director of medical and pharmacy operations at LMD.

[00:00:28]And I'm Sam Thompson. I'm the medical and pharmacy operations manager. And today we are so thrilled to welcome back Dr. Ton Tatiana Habanova, a board-certified chiropractic neurologist and functional medical medicine practitioner with over 25 years of clinical experience. As the founder of Palm Beach Brain Center, she focuses on neuroperformance, hormonal health, concussion recovery, and long-term brain vitality. Dr. Dr. Avanova is nationally recognized for her work in functional neurology and women's health. She's passionate about guiding individuals through midlife changes, helping them manage brain fog, hormonal shifts, and metabolic health using advanced tools like peptide therapy. Her unique approach combines neuroscience, longevity science, and practical wellness strategies to help people feel sharper, stronger, and more vibrant at every stage of life. Dr. Dr. Habanova, we are so grateful to have you here.

[00:01:27]Thank you for coming. We're You've mentioned before that the future of brain health isn't just about surviving.

[00:01:33]It's about optimizing how we think, feel, perform, uh, and age. Without giving away too much information, what makes you excited for the future of brain health?

[00:01:43]>> Well, thank you so much, ladies and thank you for having me this evening.

[00:01:47]I'm excited about this conversation and that is such a great question because we are at a point now um where we know that the brain actually is adaptable that it is no longer fixed as it once was thought for for a very very long time that sort of the brain you have is the brain you have and things happen throughout your life injuries or whatnot metabolic things that that's just sort of what happens if there's cognitive decline or you know changes to brain health and brain function mental health mental function then that's just sort of how it is and that is so not the truth anymore. We now know that the brain has the ability to rewire itself and neuroplasticity is the way we go about doing that. And so I'm excited about the future of brain health and longevity um particularly because of powerful tools like peptides that allow us to u make those you know longevity changes and really thrive and optimize in all stages and you know times of our life. Um, so it's been really a rewarding uh path that my career has taken over multiple decades um as it's evolved uh over time and I'm just excited about what's possible for people.

[00:02:58]>> I love that. I think it like gives people hope to know that, you know, they're not stuck this way with effort or additional assistance. Like you can really change the outcomes of your daily life and just the growth mindset is so important. And this kind of ties into maybe placebo effect. Is this something that researchers maybe first kind of started thinking about when they saw a placebo effect with medications?

[00:03:26]>> Well, um, sure. Definitely placeboex is very real. Um I mean just you know you'd mentioned mindset and so the thought the belief system around something if one believes that something's possible then it most likely will be and then also the noibo effect uh which is the re reverse of that and if I may share a quick story something that really shifted uh how I viewed um a lot of things actually and particularly the belief system was uh an experiment was was done quite many years ago now but It had the researchers had two groups of patients. One who um you know were just very anxious, right? They were just really highrung and they needed something to calm them down. And then the other group is the opposite.

[00:04:12]They were a little low, you know, maybe a little bit in depressed and they need some kind of something to pick them up.

[00:04:17]Yeah. So these are the two groups and the researchers had the medical doctors work with each team and the um researchers gave the physician the medication to give to the patients. So the physician was in the blind basically and what they believed. So for the group with the people who were very anxious and they needed something to kind of chill them, calm them down, they were the the physician believed he was giving them something to calm them down. But actually what the researchers gave that physician was was stimulants. Um so you don't want to give someone who's already kind of anxious a stimulant, right? But that's what they were given. And then the contrast in the other group, that physician believed they were getting um medication to give the patients that were depressed something to lift them up. But actually they were given depressors, anti depressants actually.

[00:05:06]So, so what ended up happening is, believe it or not, what the physician believed they were giving and the patient believed they were receiving was opposite, which actually was in the medication. But guess what happened? The people that were anxious chilled out and the people that were depressed had a little bit more lift. So, it just goes to show that that mindset really overrode the, you know, chemistry and the pharmarmacology of the medications that were delivered. Um, and that really just stuck with me when I was, you know, a young physician. Um, and I was like, "Wow, it really does it does matter."

[00:05:41]And so that's why being able to share information like this for, you know, with your platform and your audience to say, "Yes, brain changes are possible.

[00:05:49]They may take time and they need the right tools and they need the right strategy for each person is obviously very unique. Um, so we want to have personalized medicine and personalized approaches, but it is possible for every single person.

[00:06:03]That's I love that study and that like takes it a step further than those studies that do just a sugar pill, you know, like this is giving you the opposite. And the fact that you're getting the opposite effect just shows how powerful the placebo effect is in mindset. Is there like a practical tool or practical tool kit that someone watching today can take away from that study and from that idea of placebo effect?

[00:06:28]>> What do you mean by that? like in terms of >> everyday tools, tangible um you know practices that would >> Yeah.

[00:06:37]>> Yeah. Absolutely. When we look at brain health and and wellness um and you know longevity medicine especially around uh brain performance many people usually think about that around cognitive performance particularly of course the brain can do many many things uh but cognitive performance is really the important part of that. or executive functions, uh, memory, planning, organization, you know, things like this, motivation, etc. Um, so that's really what people want to be able to continue having. And so when we think about that, we can't just take a oneprong approach because brain health or cognitive health is is not that.

[00:07:15]There are multiple components that put together will improve brain health or cognitive vitality. And so we do need to consider each of those things. So what are things what are some of the major departments we want to consider right so first and foremost sleep sleep is inc incredibly important for the brain for a variety of reasons so we want to make sure that we're creating good quality sleep good quality sleep hygiene habits good architecture to sleep etc and looking at why maybe sometimes people aren't sleeping as well as they could be or should be right so we can always unpack that if we need to later in the conversation the other part is obviously exercise. So we know that the same pathways that promote movement especially in the legs in the lower part of the body where we have more muscles than our upper body but literally all muscles are are game. Um as we exercise our muscles our muscle skeletal system we actually are piggybacking off of the same cognitive pathway. So we got to remember the brain is a network right?

[00:08:18]So there are single pathways and and you know this neuron connects to that neuron etc. But there's hubs and networks and we need to work in concert together. So by being physically active and being able to move through space that feeds the brain and that's really important in particular for the frontal lobe where cognition lives. The other things we want to look at is diet. So you know exercise and diet always go together.

[00:08:43]And when we think about that, we want to make sure that we're eating quality foods, good macro nutrients, of course, kind of taking out all the chemicals and preservatives and things that we know that aren't healthy for us and minimizing our sugar intake. But more importantly, when it comes to brain health, we have to look at carbohydrate metabolism and how well does that person's body or system handle carbohydrates.

[00:09:08]So if someone is having a hard time managing carbohydrate metabolism, they're going to create like an insulin resistance kind of situation and metabolic syndrome and that significantly affects the brain. So the you got to remember the brain's a very metabolically active tissue. It uses at least 20 to 25% of your caloric intake a day just to keep the lights on and running, right? And do all its processes. So it's very metabolically demanding. And if one can't um have access to good quality sources of fuel, which for the brain would be glucose or fats for fuel. So if we're not able to make enough energy for the brain, then that is an issue there, right? So we really have to think about that and we think about what goes on the vascular system. So as well, we need to be looking at what our vascular health is, especially as as women enter into those permenopausal menopausal years. there is a significant change with obviously the hormones and estrogen particularly. So that has consequences not only in the brain itself because there's a lot of estrogen receptors in the brain. So it changes the ability for the brain to utilize fuel efficiently and so that becomes really tough. Um and then also vascular the vascular system starts to have uh you know challenges as well when estrogen is not as present. The the vascular system isn't as flexible. So we have to look at that cardio metabolic effect as well as not in the body but also you know in the brain and lastly looking at stress and um inflammation right we hear the word you know inflammaging as we age we just naturally start having more inflammation and that's very true but there's also many reasons why people have quoteunquote stress not only maybe in their um world where they have psychological stress emotional stress from our demands we have with our families and obl obligations and things. But there's also times there could be a lot of internal metabolic stresses or processes that are occurring that may be a little bit out of control or disregulated. So inflammatory processes, autoimmune conditions that may be known or unknown that are occurring, viruses, bacteria or other type of pathogenic organisms that are living within inside of us and are causing some issues, right? Um etc. So that whole category there is another important aspect to consider. So when we think about brain health um you know there's there's a lot of different sections to consider. [laughter] >> Yeah. It's so interesting that you bring up of how like metabolically active our brain tissue is and I've even noticed it like after a really long or hard day at the office I feel so hungry. I feel really drained. Um, and it gets me thinking people who may have like insulin resistance or who are good candidates for GLPS. How can GLPS affect this kind of inflammation and metabolism in the brain?

[00:12:03]>> Absolutely. That's a really great question and um the research is starting to really expand and it's been really exciting this last year to watch this um area evolve and and grow as it needs to.

[00:12:15]Um so there's really a lot of movement in the research space now around GLP1s moving them away just from um weight loss which of course is necessary too.

[00:12:24]So I'm going to answer this question kind of from two approaches. Um because if someone is has a BMI where they are obese then that itself is uh you know has so many core mobidities you right.

[00:12:37]So just having the ability to bring one's body weight down and and ideally we want to lose body fat not muscle mass. So there has to be some appropriate coaching and guidance around the use of a GLP1. Um, and I have to say I'm always really impressed on how much LED does for um, education. Um, not just even the vets like this tonight, but just continuing to provide that knowledge that's needed. Um, so that that is a necessity if someone is in that situation. Definitely losing body fat will make a big difference because of all the metabolic elements, the inflammation that occurs and the core mobilities that exist. But GLP ones have been starting to be shown that beyond the weight loss aspects that there are so many additional benefits, especially people who have a BMI that falls into more of a an appropriate range and so they don't qualify for the GLP1s that would be for the weight loss dose versions, right? So there are now micro dose versions for for that. And we know that from a brain health perspective, bone health, kidney health, liver health, heart health carry on. I mean, pretty much every organ system has GLP-1 receptors and there is value there um that's occurring. So, we're seeing that across the board. Um, so yes, definitely the ability to have better control over your glucose metabolism, the ability to break down carbohydrates and not create an insulin resistance, which just basically means that when you consume carbohydrates, they're living in your bloodstream for longer than they should.

[00:14:12]Generally, when we eat, glucose will obviously increase because we've consumed some carbohydrates in our meal, and that's okay. But within about 2 hours they need to go into the cell and start being broken down for fuel for a variety of reasons. Well, obviously we we need the energy from those carbohydrates to create fuel. You know, we need the energy to do things in the body. Okay, so that's a necessity. But we also don't want the glucose lingering longer in the bloodstream because this is where we start creating damage. the actually glucose who's very good is going to start making issues in blood vessels and kidneys etc. Okay. So it becomes a glycosillated end product and that's not a good thing to do. And that when that happens it's because insulin sort of the locking key that's supposed to open the door of the cell and let the glucose in um is kind of not allowing that process to happen. Um so definitely using JLP1s to help manage um that situation has been I mean I personally feel everyone should most likely again depending on your case and scenario but um from a longevity perspective to have some support as we age um on in that category even if you're very dialed in with your health and nutrition and your exercise. So again, it's all case specific, mind you, but for the majority of people, that could be a valuable consideration for their future health.

[00:15:39]>> Really helpful with elevated glucose levels like in the brain if it's not being taken up by ourselves. Can that cause brain fog in people? And can you talk about brain fog and what may cause that?

[00:15:52]>> Sure. Sure. Yeah, brain fog is um was on a diagnosis. That's just a word that people use to kind of describe a little bit of kind of what's going on. Um, and again, they're generally usually referring to some like cognitive aspect.

[00:16:04]They can't, you know, they they can't the the word recall, right? It's just the tip of the tongue moment. Uh, forgetfulness, little cloudy, the clarity is not there, right? Their heads in the cloud sort of idea. So, definitely. So, couple things could be happening. If we're not going to be able to provide adequate fuel source to the brain, the neurons that actually need to fire and do these functions, we're not going to get the function. So here we are. So definitely the same type of insulin resistance that can happen in the body happens in the brain.

[00:16:36]Absolutely. Absolutely. The brain that has a choice to perhaps utilize fats for fuel. So now we we're opening up a conversation of well how metabolically efficient is the cells right of the brain? Okay. So that's kind of it kind of opens up the conversation to you know things we can talk about um with NAD and MSI and various things too and using like obviously the JLP1s and modifying people's diet and exercise and lifestyle integrations. The other thing that can create brain fog that people sometimes don't realize is there is inflammation.

[00:17:09]If there's systemic inflammation, there's going to be neuroinflammation.

[00:17:12]And there can be neuroinflammation because there's stuff going on in the brain causing neuroinflammation or there could be a leaky uh brain a bloodb brain barrier that is allowing systemic inflammation to come up into the brain.

[00:17:27]So, and that could be for a multitude of reasons. Um, so sometimes people don't even really realize things that might be happening that might be affecting them.

[00:17:36]Um and then the other aspect is obviously thyroid just making sure one's thyroid um levels TS you know TSH T3 T4 etc are appropriate too. So some sometimes we need to just do our yearly blood work and double check or maybe do it even every six months to make sure that that's not the issue there.

[00:17:57]>> It's really interesting. Yeah. Yeah. So just thinking about the body uh as a total because I know you're talking about systemic inflammation as well.

[00:18:05]Moving on to the gut. A lot of people refer to the gut as the second brain. Um the brain body connection. Brain gut super important. Uh can you just talk a little bit about that? Is that real? The brain gut connection.

[00:18:18]>> Oh yeah, absolutely. For sure. Well, you know um in our in our gut the I mean health to me health and my philosophy and my approach to to vitality and optimization is you know for me health start health starts in the gut. So it actually starts by chewing. It starts in the mouth. But we want to make sure that we have good quality uh assimulation digestion and uh then the flora. So making sure that the flora in our gut is appropriate. We don't have pathogenic bacteria, viruses, parasites etc living there. Um hopefully the garden is good and that we have a a nice diversity of commensal flora good bacteria that live in the gut. Right? This is so needed. We this is a very symbiotic relationship.

[00:19:02]Uh, so we want to make sure that's occurring, but we also have to make sure that the gut lining, just like we talked about the bloodb brain barrier, we have to make sure that the gut lining is also intact and not leaky, right? Um, and for whatever reason, there could there could be many things that cause irritation or a leaky gut, right? So, an inflammatory bowel disease, Crohn's, I mean, now we're kind of getting along in the spectrum, but from the simplicity state, there can be inflammation that lives in the gut. And that alone will just create a disruption at the gut level and the things that come from the gut in the terms of proper digestion, assimulation of nutrients etc. Uh but then the relationship to the brain for sure there's you know many neurotransmitters that are made in the gut especially serotonin for example which is very key uh because it goes off to also make melatonin. Uh but serotonin is our happy hormone. Yeah. Happy molecule. So we want to make sure that we're supporting our gut health as well as our brain health. So yes, that gut brain axis is connected. And if I could just add one little piece in terms of showing that relationship from another perspective, we know from concussions that when someone sustains a concussion within 24 hours, the uh not only the brain but the gut uh barrier becomes leaky and generally what I see in my practice is about a six months to a year later there are autoimmune conditions.

[00:20:26]So, when we have undigested food that's coming down into the gut and we have a a leaky gut situation, that undigested food is being absorbed, it's quote unquote foreign. And now we start to create an heightened inflammation, immune dysregulation, and over time we have a named condition, right? So that that now becomes problematic. we have a lot of immune dysregulation, more inflammation and you know depends on what the actual condition is, it could wreak a l lot of havoc. So >> luckily we have ways to simmer all that down and to heal those situations and improve upon them. So [laughter] >> yeah, we can address the brain, right?

[00:21:11]We know we have neuroplasticity and the ability to change that. But if someone did, right, develop gut issues and leaky gut, it seems like it may be a little harder to reverse, how like how would you suggest a patient go about that or someone that's experiencing gut issues and wants to heal? What are some steps that they can take?

[00:21:31]>> Absolutely. So, there's a lot of tools available. Um, one of the things I like to do in my practice is I'll actually have patients do a um a a stool analysis. And this will tell me first and foremost, am I dealing with any pathogenic bacteria, viruses, parasites, anything that and many times I actually do pick things up that people didn't even realize were there. So then we need to get some medication to treat those things, right? Okay. So we want to check mark maybe we don't have any pathogenic bacteria, viruses, parasites, etc. moving forward. So now we want to identify, you know, what potential triggers that has the system developed around foods they might be eating. So if we have any food sensitivities that we might want to consider, we know that gluten is a huge disruptor to all barriers, gut barrier, brain barrier, sinus barrier, inner ear barrier, heart barrier, all the barriers, lung barriers. So when you're having a leaky gut, you're having leaky barriers pretty much in all the barriers. Okay? So thankfully when we heal the leaky gut, we're healing all the other barriers too. Um so it kind of goes both ways. So gluten, corn, dairy, um usually culprits. So trying to identify um the triggers for people to eliminate them to to reduce the burden basically is what we're trying to do. As we start to do that, we still want to make sure we're eating well and we need to start healing the gut. So there are protocols to help support the gut. And one of my favorites actually because it's just such a powerful lever is to use BPC157 TB500.

[00:23:01]Um you know that's kind of one of my first recommendations to people um for that because it's so powerful at at healing the gut the inflammation as well as many other things with muscle skeletal injuries and things like that.

[00:23:14]It has benefits um in the body as well.

[00:23:16]But from a gut perspective uh that is you know very useful but we want to remove the triggers right. So we need to reduce the burdens and then support the system basically. Um so it is a bit of a process but it is possible. And then there's various neutrauticals that can be used to just support the gut as well.

[00:23:34]The gut turns over every about six days or so. So it's very regenerative and we want to keep supporting it and removing the burdens basically.

[00:23:42]>> Yeah. Is there a way to because I know we're talking about treating the gut to also treat the brain. Is that does it reverse as well? Like when we're thinking about and also just like maybe we tie this into talking about energy earlier like if we're thinking about peptides for the brain like NAD or if we're thinking about CAC link to help heal the gut or the rest of the body.

[00:24:03]Absolutely. Well, I mean anytime you have to do any type of healing regardless and and first of all also just regeneration every every day cells are turning over. You know, every day we're making new cells, right? red blood cells uh more or less every three to three to four months is their lifespan right liver you know every six days gut every you know so things are constantly turning over so we need energy for that just just to kind of maintain the house so to speak right but if there's any area that is having a burden placed on it and more you know metabolic processes that have to go the immune system has to be present now at the gut that's very heightened the cells are being destroyed or disrupted now they have to heal we need energy for all those processes. And so as people get burdened with various conditions, all right, that is taxing their system, the need for energetics goes up. And so we c we one but I find patients generally think their own body should give them enough energetics to do that. it's a little bit um sometimes not realizing that we actually actually have to support the energetic processes so that we can give the necessary you know energy eventually making ATP for the body to do what it needs to do then that currency goes up right it's almost like if I don't know here in Florida we get hurricanes so people's rooms fall off all the [laughter] time when there's a hurricane so you know your house got damaged your roof is missing you know you're going to now need to replace it now hopefully maybe the insurance company can cover it. But either way, say it's out of pocket, you're gonna have to like pay for it, right? You're gonna have to come up with extra currency. So, we look at ATP like currency. So, definitely as we age, um, as we get older in life, our abilities to make energy naturally do go down. So, that's another consideration just where somebody is, if they're in their early 20,30s or 40, 50s, 60,7s, um, the need does increase for energetics. So like NAD you mentioned is a great uh co-actor is it is a co-actor needed to produce energy through the m in the mitochondria. Uh but supplementing or supporting that and bringing more NAD for example in our system just makes that much easier and then healing can happen much faster and better. The other thing is when a person's really burdened with whatever might be going on they're exhausted. They're so fatigued because the body is really stealing the energy to try to heal. could care less about your deadline or your work schedule or you have to pick up kids or whatever the obligation is in one's life. Um so it really just goes to survival. Yeah. So if you're also trying to carry a full plate of life obligations, whatever that might be for you and whatever season of life you're in, um you know, that's another aspect to consider. And if sleep is a bit disrupted and it's not restorative, you know, we're not cleaning house, right? We're not kind of rejuvenating.

[00:27:02]We're not doing some of the regenerative things like growth hormone production and how it's pulled throughout the evening. And so some other tools and other needs in our body that we lean into may not be also there to support us that next day.

[00:27:15]>> So it really is kind of a full picture of things to consider. So yes, so definitely healing and energetics are very important. [laughter] >> Yeah, I think today's day and age, we're just constantly inundated with technology advertisements. Our brains are always on and I hear the term burnout. It's just increasing. It's becoming very well known and more and more used. Can you talk about burnout?

[00:27:41]Right. Is it a diagnosis? And how do you define if someone's experiencing burnout?

[00:27:48]>> Absolutely. I mean the the life has just gotten busy honestly, right? And and people are taking more and more on and yes definitely burnout is real. Um you know there could be a lot of different versions of burnout but just not being able to just do what one wants to be able to do. Um, and certainly energetics come into it, but also what happens is, and I might be taking this a little bit in a slightly different angle than what you meant, but when there is so much going on in life's demands and the responsibilities that people have, obligations, and even desires and choices of things they want to do every day and have happen, you know, a lot of people have a lot of passions as well as obligations. But it could become when you're not supporting the system and the system's getting a little bit behind the eight-ball, a sense of almost like inner anxiety can start happening. And I don't mean that you're a person who might have more of the anxious side or that that um predisposition. I just mean for anyone that's just going to be more stress and it's going to cause a sense of overwhelm or a sense of time urgency or just not be able to get to everything or have the energy to get to everything and then feeling bad about not being able to do that or where whatnotss, right? So now there's just so much more stress being added on to the equation besides a busy ready life or a full plate or whatever the case is. So I think personally we're in a stage in our society and I wouldn't have said this 25 years ago when I started practicing because life was very different in the late 90s and early 2000s than it is now. Right? Um, but really being mindful to consider the regenerative aspects we must give ourselves and to recognize the burdens and and the demands that we're placing on ourselves and that we're not super human that you know there's a lot of expectations and a lot of pressures and sometimes we take it on ourselves. Uh so nothing I'm all for supporting people and challen like let them challenge themselves to do more be more you know I like to empower people but at the same time respecting that these systems need time to rejuvenate and heal and if you're going to if you're going to work hard you know if you're going to play hard you better than support your system. So I work with a lot of top performing athletes and they train hard but they rehab hard as well, >> right? So they don't go out there and and you know kill themselves and then just assume next day they can do it again, right? Yeah, they probably get away with it when you're a little younger. You kind of can get away with it, but that's not even smart anyways, right? So they train hard, they they work hard, but they rehab hard, they take care of themselves just as hard. So I think that's something um a thought that we should take into our everyday lives because we we all are, you know, superheroes, right? In our own worlds.

[00:30:32]We do so much for for our families and ourselves in the world. So we need to support ourselves a lot more than we are.

[00:30:39]>> I have like a question that's kind of like a double-edged sword almost. As we age, are we more susceptible to burnout?

[00:30:46]But I also want to consider too as you age, you get more life experience. Are you more equipped to deal with more stress?

[00:30:54]>> That's a really good point. So, yeah, I I I agree with you on that one. That is a double-edged sword. So, I mean, again, we have to go back to defining stress.

[00:31:03]So, when we talk about stress, are you saying psychological stress, emotional stress, mental stress? Are we talking physiological stress, right? Chemical um stress, metabolic stress, right? So, you know, stress is good. um stress, you know, a cold becomes a diamond with given the right pressure, right? So, um so we don't want to stay away from stress. We want to be able to handle stress better and manage it and not get behind the eight-ball. If you know, in case we do, then we need to support ourselves to get out of it. But we want to have resilience. You know, I think that's more the mindset we want to be looking at as we move forward. How can I have resilience to that? So, as one gets older, life experience, you know, comes to hand. So maybe that's, you know, part of the resilience is just going through things more often than knowing how to handle them better, right? Not letting them wear and tear on on someone so like on yourself so emotionally, right? Um at the same time, living on this planet and being exposed to oxidative stresses and environmental toxins and a life of whatnotss, right?

[00:32:08]um if that hasn't been dealt with they accumulate in the body and they will add burdens and then there will be more metabolic you know stress or demands right so I think yeah I think that's a really good question [laughter] but stress is needed stress is good uh I encourage my patients to take on a little more stress in their life but appropriately right and then to have the support and the resources around them um the tools available to, you know, re, you know, rejuvenate the self, the mind, the body, the soul. Right.

[00:32:44]>> Thank you for that. And I'm just monitoring the chat. We have some more specific kind of patient health center questions. We'll be sensitive when answering those since we don't know your whole history, but can you speak on essential tremors? If you've dealt with patients in the past, have you ever seen peptides that address this?

[00:33:03]>> Yeah, essential tremors. Um Chris, I just have to answer this um very generically. Um so primarily from a neuroscience perspective, there'll be an area of the brain called the basil ganglia that's just below consciousness and it's kind of the go no go. It's the gas and brakes. So it's going to allow something to go through like a movement, a thought, a feeling or it's not. So something when you think about brain about the brain, you got to kind of think of it like the brain's like your car and let's say you pull up to a red light and you've got your foot on on the brake, right? Because it's a red light, you don't want to move forward, but the engine's running. So the brain is always on and the brain actually always wants to be excitatory. It always wants to fire, but we need the inhibitory pathways and the inhibitory uh regions in the brain to be working to put the brakes on because otherwise our hands and everything would be moving all over the place all the time, right? So, we want to make sure that when we want to go, we move our foot from the brake to the gas and we move, right? So, we're going to move a hand or speak or whatever the case is. a a tremor. And there's a variety of different types of tremors, but an essential tremor is going to be when that break gas break gas break gas. You know, have you ever had someone who kind of just sort of creeps along in in traffic, [laughter] right? So, they go stop go. So, the basil ganglia is allowing something to go, but then it's inhibiting that allows it to go and inhibits. So, it's it's it's just like a stutter almost, right?

[00:34:36]It's this like little tremor. So, we really need to try to modulate that. And of course we need to look at the dopamine regions in the midbrain and what's going on in the substantionigra and you know what's happening in our cerebellum and our frontal loes. So there's again hubs and networks and connections. So do peptides to try to go back to the question do peptides help?

[00:34:57]Well that's a hard question to say directly because that would be a multifaceted approach. I've worked with patients like this and I have been able to bring their tremors down to, you know, a much more manageable situation.

[00:35:10]Have peptides been a part of that equation? Yes, based on that patient's needs. But as a general, I wouldn't just immediately think essential tremors peptides. I wouldn't jump to it, but it can be part of the equation. It just depends on what's going on.

[00:35:26]>> Yeah, I'm thinking of sank here. I mean not that but just that that it does address our GABA neurotransmitters which is our breaking system and calming system and >> definitely definitely that would be one of the levers to lean into um because if there is too much excited toxicity in the sense where there's too much excitatory uh neurotransmitters going on or pathways and we don't have those breaks uh so you know could be a very valuable tool um in that equation. Will it do it all? Perhaps. Will there need to be a little more? Perhaps. Right. So, that really kind of case specific, but it would be something worth considering.

[00:36:06]Super interesting and helpful to know.

[00:36:08]Um, I know we are coming up on time. So, just as we wrap up, is there one thing that you'd want people to know and walk away from today and in terms of how to optimize and protect their brain health >> and mental health? Yeah.

[00:36:22]>> And their mental health. Yeah. I think the biggest thing is to know that the brain has the ability to rewire and we have the ability um especially if you're working with trained professionals who can guide you and support you but you yourself have the power in your hands to support your brain health, body health and um really redefine your life if it's going in a way that it's not what you want. The the ability is always there and that there are tools to support you multiple tools. peptides can be certainly a part of that, but that the brain is resilient, you're resilient, the brain can reheal, the brain can, you know, become optimized at any age, at any age. Um, and so that that's always possible. And if somebody tells you different, then they're not up to modern science and don't listen to them. Um but that our you know our outlooks on life, our mental well-being and all the neuropathways that are existing in the brain that bring out mood and emotion, all the pathways that exist to allow us to be dynamic and functional um you know can be optimized continuously throughout our whole life and it's very exciting.

[00:37:29]So I bless that and wish that for everyone.

[00:37:32]>> Thank you so much. This was really really helpful and it's just scratching the tip of the iceberg. There's so much more we want to learn. So, thank you for joining the community this evening. And if you were invited by someone, please send a thank you to them. Just let them know how it went. Um, thank you all and have a wonderful Thursday. Right, we'll see you next time. Bye everyone. Thank you.