Hormone therapy is beneficial when started within 10 years of menopause, but the Women's Health Initiative study's inclusion of women up to age 79 created a physiological mismatch that led to widespread misconceptions about its dangers; when initiated closer to menopause, hormone therapy is associated with longer lifespan, reduced cardiovascular disease, and better bone health.
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Deep Dive
Hormone therapy was labeled dangerous for years.Added:
Hormone therapy was considered kryptonite from 2002 onwards. Although, there's been so much data and [music] evidence to the contrary to show how safe estrogen is, to debunk [music] the myth about breast cancer risk, and to show that when it's taken within 10 [music] years, women do fantastic. They live longer. They do have less heart disease. They do have better bone health. The problem and the discrepancy really was that when they were looking at those prospective studies [music] in the '80s and in the early '90s, women were given hormone therapy right around the time of menopause. Whereas in the Women's Health Initiative, they were much older. In fact, the age range was 50 to 79. So, you had women in their late 70s that were given hormone therapy for this [music] trial. That really mixes up physiology, right? You have different stages of life, women who maybe are not as healthy as they are today. And so, that kind of landed us in this whole like, is hormone therapy bad?
So, a plethora of data shows that it is good for us. And that's kind of why we're here today. Is because we are still breaking down those myths and misconceptions.
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