CRP and ApoB Are Better Cardiac Markers Than Cholesterol

Added: 2026-05-27

[00:00:00]Did you know that there's a much more accurate and effective way of measuring your cardiovascular risk on your blood work that most doctors aren't even looking at? You see, most doctors are spending their time looking at your cholesterol levels and then putting guys on things like statins or high LDL, fear-mongering them into thinking that they're going to have a heart attack.

[00:00:21]But the thing that actually causes heart disease is particles penetrating your arterial wall. And every single one of those particles carries exactly one molecule of a polipalle protein B on its surface. So when you measure APOB, you're counting the total number of particles that can damage your arteries.

[00:00:40]When you measure LDL cholesterol, you're measuring how much cholesterol is packed inside those particles, which varies from person to person. Two people with identical LDL cholesterol can have completely different particle counts and completely different cardiovascular risk. In fact, a meta analysis of over 233,000 people in 22,000 cardiac events found that APOB was 12% more accurate than LDL cholesterol at predicting who actually has a heart attack. And in the inner heart study across 52 countries, the APOB to the APO A1 ratio was the single most powerful lipid predictor of heart attacks, beating every cholesterol ratio in every ethnic group. The second number that you want to look at is high sensitivity CRP, which measures inflammation inside of your arterial walls. The Jupiter trial enrolled over 17,000 people who had normal LDL cholesterol, but elevated CRP above 2 milligrams per liter and treated them with a statin, which dropped both LDL and CRP simultaneously. The result was a 44% reduction in cardiac events. And the fact that these people were selected by elevated CRP alone shows that standard lipid panels were missing their risk entirely. About 18 to 23% of the general population has normal LDL cholesterol but elevated APOB. Those people are being told their heart health is fine while carrying a high number of damaging particles their doctor never measured.

[00:02:18]So ask your doctor to add APOB and high sensitivity CRP to your next lipid pen.

[00:02:24]And if you want help understanding what your blood work is actually telling you, I actually break down labs like this inside my free community. If you want access, all you have to do is just go down to the description of this video, tap the link to sign up.