Hantavirus is primarily transmitted from rodents to humans through inhalation of aerosolized rodent waste, but the Andes strain can spread person-to-person during prolonged close contact, as demonstrated by the 2004 outbreak on the MV Hondius cruise ship where Dutch ornithologist Leo Schilperoord became patient zero after visiting a contaminated landfill in Argentina, subsequently infecting his wife and other passengers through shared ventilation and close living quarters.
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Hantavirus outbreak, patient zero, and how it spread onboard cruise ship explained in five minutesAjouté :
So, they've identified patient zero in the Hantavirus outbreak as well-known Dutch ornithologist Leo Schilperoord.
Hey man, as what is an ornithologist?
That's a scientist that specializes in studying birds. So, I'm going to explain the timeline to you and why you should not be worried that the Hantavirus will be the next global pandemic. Leo and his wife were reportedly on a 5-month bird-watching trip which included the cruise. And back on March 27th, just a few days before boarding the cruise ship, Leo and his wife were traveling through southern Argentina near Patagonia and they went to a landfill that is popular amongst bird-watchers to spot the rare white-throated caracara, also known as Darwin's caracara. And health officials believe that that area may have been contaminated with feces or urine from the long-tailed pygmy rice rats that are known carriers of the Andes Hantavirus strain. Now, that's where this comes into play. The likely inhaled the aerosolized viral particles, which happens when rodent waste is disturbed and aerosolized like in landfills. Now, typically this virus is a rodent-to-human transfer. The Andes strain involved in this case is the only Hantavirus that can actually spread person-to-person, but it has to be during close prolonged contact like a cruise ship. So, on April 1st, Leo and his wife boarded the MV Hondius that departed for its expedition voyage. And on April 6th, Leo began to develop symptoms: fever, fatigue, muscle aches, and very flu-like initially, but things escalated and on April 11th, he died on board the ship. And at the time, the death was reported to be thought to be from natural causes and the ship continued its route before eventually reaching St. Helena on April the 24th.
Now, the incubation time for the virus is 1 to 6 weeks. Around the time of April 24th, Leo's wife became critically ill herself and she was medically evacuated by a plane to Johannesburg, South Africa and 2 days later she died.
Another passenger, we're just call them passenger number three, was flown to South Africa on April 27th. Now, this is the point when the health officials began to suspect that this may be hantavirus, specifically the Andes strain because transmission with the Andes strain person-to-person requires prolonged close contact with an infected person, particularly during their peak symptoms. When he was coughing a lot right before he died, which is about 2 weeks before she began to develop symptoms, the incubation period. Now, just a brief note on the hantavirus, it it can cause severe pulmonary disease and it's associated with something called hantavirus pulmonary syndrome or HPS and it often starts with a viral illness like fatigue, muscle aches, nausea, headaches and then some people rapidly develop into this cardiopulmonary phase. Cough, shortness of breath, fluid builds up in the lungs, respiratory failure, shock and that's what makes hantavirus dangerous is how fast that that decline can happen. The virus essentially causes a capillary leak syndrome, so fluid leaks into the lungs making oxygen exchange extremely difficult. So, back to the story. On May 2nd, the PCR tests come back on Leo's wife and passenger number three to indeed be the hantavirus. So, the WHO contact tracing begins on the disembarked passengers and then on April 2nd, another patient reportedly died on board where their symptoms started on April 28th. And by May 3rd, the ship reaches Cape Verde and now the international public health agencies are fully involved. The passengers begin isolation and monitoring procedures on board while the contact tracing ramps up globally and then cases five, six, and seven on board the ship remained on board until recently this past Wednesday when they were evacuated and there is reportedly another eighth case who was a passenger that disembarked before the outbreak was detected and is being treated in Zurich. And so that's all the cluster cases that are identified for now, eight cases and a cruise ship is a perfect environment for this type of virus to escalate. Shared ventilation, confined spaces, prolonged exposure, dining together, closed living quarters for days to weeks, and that's why authorities are isolating symptomatic passengers, tracing contacts, disinfecting the ship, and quarantining exposed individuals and that quarantine is going to interrupt the possible chains of transmission early before this outbreak continues to grow. Now, I know stories like this sound really scary online when you hear the words outbreak or human-to-human transmission, especially since we're so traumatized from COVID, but please be reassured that the hunt for virus is not something that spreads easily like COVID or the flu for the most part, guys, we are safe. That's why public health strategies and knowledge is so important.
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