Synthesis Review

Added: 2026-05-05

[00:00:00]All right, so we're going to keep the surprise me as our starting material.

[00:00:04]Let's change our product.

[00:00:06]>> Let's bring that in. Surprise me to surprise me.

[00:00:10]I will. So, your surprise me is going to be going from a benzene to whatever this is. We go from a benzene to an enamine? Good. Can I use acylation here or no?

[00:00:24]You can. Really? Because >> away from it, but I feel like I could practice more with it.

[00:00:29]>> You could. And then it's remembering that it forms what? What does acylation add on to the ring? Acylation adds a carbonyl and R group. It adds a ketone.

[00:00:37]Oh, ketone specifically.

[00:00:39]>> Right, yeah, specifically a ketone. And then we know, okay, an enamine, Mhm.

[00:00:43]that goes back to the aldehydes and ketones chapters, so that works.

[00:00:47]>> That works, yeah. That's So, let's do it.

[00:00:49]>> Okay. Good. That's correct. And let's build it. Perfect. That's correct. We formed a ketone. What's next?

[00:00:56]Is it cuz you dropped the H, so it's NH with two methyls? Okay. Or like two R groups?

[00:01:02]>> You're right. Two methyls because we added those. That's right. Are we missing one thing? Is there an acid? Oh, there is. Okay.

[00:01:11]So, it would look like that. That's correct. This is an enamine formation.

[00:01:14]Oh, this is good. So, I'm so glad you didn't shy away from using this.

[00:01:18]>> I always get scared. I don't know.

[00:01:19]There's so many things with that one.

[00:01:21]There is, but the main thing here was there's nothing on this ring that we have to worry about.

[00:01:26]>> That's true. Then we're trying to form a ketone to then go back to our reactions of ketones. Knowing this is an enamine, I think that was the hardest part of this is just identifying what is it.

[00:01:35]>> Mhm. That's true. So, you did that those steps and we're done.