NIPER JEE 2026 | Medicinal Chemistry: Complete Syllabus | 360 Series #niperpreparation #niperexam

Added: 2026-05-12

[00:00:00]Hello dear students, welcome back to GDC.

[00:00:03]In the Sniper series, we are going to talk about important questions related to medicinal chemistry.

[00:00:09]Let's ask your important question, it is 360°, right? Medicinal Chemistry Complete Syllabus will be discussed. The important questions are the ones that have been asked before.

[00:00:19]We will discuss on that basis.

[00:00:21]Ok? So in medicinal chemistry, you know that in NIPER, some drug designing based questions and ring based questions have been asked. Mainly drug designing based questions remain. So whatever question has been asked related to it, we will talk about it and discuss it.

[00:00:35]Ok? So here we are, let's get ready everyone. Let's discuss it one by one. Isn't it? Whatever previous question you have, like the first question was asked today.

[00:00:47]What is C asking? Which of the following contain the pyridine ring. Isn't it? When did you ask?

[00:00:54]This question was asked in NAPER JE 2025. Ok? This question of yours has come in 25 that which one is Pirdin, right? Pyridine ring is present in which drug?

[00:01:05]Right? So what will be the option? See the correct option, what is there here? Paracetamol contains phenol derivatives. Isoniazid is a pyridine derivative. Aspiransilicic acid derivative. And what is ibopropane? This is your benzene derivative plus propanoic acid derivative isobutyl derivative, so your correct answer is isoniazid which comes with your hydrazites in which we know pyridine ring is also present and your isonicotinamides are made from this. Ok? So option B will be correct. Here your option B will be corrected. So here's the structure of your pyridine derivative and this is your hydrazine and this is your keto group attached to it.

[00:01:49]So isonicotinic acid and hydrazides together form isoniazid anti tuberculosis drug. Ok? It is kept in anti-tuberculosis drug.

[00:01:59]What is the next question asked? Which heterocyclic ring is used for miconazole synthesis? So now this type of question is like synthesis of miconazole.

[00:02:09]What are some drugs that are your imidazole derivatives? Which one is a triazole derivative. So if we talk about the trick in this, what did we tell you? There is a VIP female, we were talking about a VIP female.

[00:02:22]So here you have Verconazole, Itraconazole, Posaconazole, Fluconazole, what were these for you?

[00:02:31]Triazole derivatives. So what's in here?

[00:02:33]Miconazole derivative will be imidazole derivative here, so imidazole is present here. This means what will start the synthesis of this drug? From imidazole. Ok? So the option A here will be corrected. Why?

[00:02:48]Because if Triazole was there, we would have seen only two categories in it.

[00:02:51]Imidrazole is available. Triazole is available.

[00:02:54]So there is no triazole here.

[00:02:55]What will imidrazol do to you? The correct answer will be given. The correct answer will be given. So if any ring based question is asked to you on its basis, then definitely yours will be correct. If we talk about its base, then if you remember the ring then we can do the synthesis also. Ok? So this is two four dichloro astrophenone, right? Why two four dichloro? This is two. This is three. This is four.

[00:03:20]Five is six. Isn't it? This was treated with bromine.

[00:03:22]Here comes the bromine.

[00:03:24]Then we will treat it with imidazole. So your imidazole is from here with the basic skeleton, it was asked which ring is your imidazole from which it will start, so from here you will synthesize a compound from your intermediate. Ok? Your next question is ring present in leibocitrizine.

[00:03:42]So what is Cetirizine Libocetirizine?

[00:03:45]Citrizin and Libocitrizin contain the Libocitrizin L form. Isn't it? There is gene. So what were we telling you?

[00:03:51]What does gene mean here? Contains piperazine.

[00:03:53]What is there here? Piperazine. So the Pipra gene is present here, in the case of citrinogen it is libocitrinogen, so yours is correct, the option purine will not be there, it is not here, it is not pyrimidine, otherwise you can correlate this gene from here if its derivatives like para gene was given, phenothiazine was given, pyridazine was given, then it seems which one is right because the gene is present in all of them, but the answer here is straight forward, yours is a very simple question, this is not a very tough question, this will be done.

[00:04:25]Ok? If this type of question comes then you can do it.

[00:04:28]So piperazine derivative this is piperazine right? It is piperazine.

[00:04:34]Chloro benzene derivative. Here the molecule contains cartilage. What do we do with its L form, its levoform? Let's use it. Right? And this one of yours has a carboxylic group attached to it.

[00:04:46]Due to which the molecule becomes polar. And Easley won't cross Triple B.

[00:04:51]What happens because of this? What is its CNS effect? It becomes laced. Age compared to other H1 blocker drugs. So this is your laxative. Next question asked in 2023 was Chloramphenicol.

[00:05:10]What is the reaction for inactivation of chloramphenicol and how does inactivation occur? It happens through oxidation or reduction or it will be hydrolysis or it will be decyclization. So chlorophenicol, if you look at it, it contains nitro benzene derivative.

[00:05:28]What is this? Nitrobenzene derivative.

[00:05:30]Two chiral carbons live here. The hydroxy group is a secondary hydroxy group and the second one will be a primary hydroxy group.

[00:05:38]So here we will see two chiral carbons.

[00:05:40]Plus what's in here?

[00:05:42]Your amide remains attached and this one of yours remains attached with chlorine here. Ok?

[00:05:49]So this is chlorophenicol. So what happens when it gets deactivated? By reduction. What will happen? Reduction. In which does it get reduced? This will be reduced to NH2. Ok?

[00:06:03]What will happen? When the acid is reduced to NH2, it becomes inactivated.

[00:06:08]So sometimes it is also asked about chlorophenol that by which method is this done? So here when reduction was done it was converted into primary aromatic amine.

[00:06:19]Ok? So it becomes a primary aromatic amine. So this can be done by dye azotization.

[00:06:23]So questions can also be asked from this analysis of yours.

[00:06:29]Ok? So this is your inactivation based question.

[00:06:34]Option B got corrected. Reduction.

[00:06:37]Ok? This will be your primary aromatic amines formed by reduction. And we will call this Airilemin and what is this? It is biologically inactive and does not show antibacterial activity.

[00:06:54]Next question is Med Formin is the drug of V class? Isn't it? In 2023 also the question was asked, which class of drug is this sniper? So here you can also be asked the question whether it is a thiazidine derivative or its derivative.

[00:07:07]So here the derivative is yours, it is not Jodin Dione, it does not even have TP4 inters.

[00:07:15]You can query this directly from the classification.

[00:07:16]Ok? This is what Bygwanides can be seen. Made formin fen formin is na you will get to see what is.

[00:07:23]Biguanites sulfonaria and chloropropamide tolbutamide are seen. So there is no sulfonylurea.

[00:07:29]So what happened to your C option? It got corrected.

[00:07:32]Option C got corrected. From here, directly, the Met Farming Derivative which is yours, this is right bynights derivative, right, this is your next question. This has also been asked in 2023. Which ring is present in warfarin? Warfarin is a common derivative but it does not have the word coumarin written on it. So if you see the common derivative here, this kind of structure of this combination is seen, this type of structure of coumarin is present to you but there is no coumarin in it. What will happen here?

[00:08:15]Benzopa to on. So let's talk about benzopyrene here two on like 1 2 3 4 5 6 7 8 So what is two on? On is on. So what's all there is to it? It is written on three.

[00:08:28]So this went wrong. This too was three on but this also went wrong. Ok? Pyrimidine is not.

[00:08:32]So what happened? Two is on. So option A got corrected. Ok? What happened to this option? It will be corrected.

[00:08:39]Benzopyrene. So this is yours, here you will see which ring is present in common? Which ring present is right? So this is your warfarin, you know, and it's an anticoagulant. Its protein banding is very high. It has protein binding up to 98-99%.

[00:08:59]You may also be asked questions based on protein banding.

[00:09:03]Ok? Let's know the full form of QSR, this is a very easy question. So what will be the full form of KSR? Ok? So here it is quantitative active structure activity relationship QSA R, right, this of yours will be quantitative, pay attention it is quantitative not qualitative quantitative, right, this option will be corrected directly, quantitative structure activity relationship, what is the number of nitrogen atoms in terbutaline 1 2 3 4, so you know terbutaline is a resorcinol derivative, if you see terbutaline then this is terbutaline, here you will see the resorcinol moiety and this resorcinol of yours, this OH is also attached, CH2 will be attached here, NH is visible here and this is your tertiary butyls.

[00:10:00]So turbata is a resorcinol derivative. There is only one nitrogen here and that is of secondary nature. Ok? So option A will be correct. Here you have a straightforward question. This means if you remember the structure then it will be done. Ok? The same condition exists in Salbutamol also.

[00:10:19]So here you have asked about turbata, so next time the mall may also ask how much nitrogen is there. What is its derivative?

[00:10:27]Is it clear? So your forest will be corrected.

[00:10:31]Right? Let it be simple, the question is structure based, here it is secondary and this is your salbutamol, here there is carotene, there is alphamect, there is terbutaline, here it is your resorsanol derivative, so this is your ring base or functional group base questions can also be asked.

[00:10:52]Bioster of the carboxylic group is now bioster asked here. Now are you talking about classical or non- classical? It has not specified. So what does this mean? Question 21 is that this may be classical for you or it may be non- classical. So the bioster of carboxylic acid is tetrazole and it is kept in non-classical bioster. So this is correct. Acid amide is exactly the amide of an acid, for example, let's say this acid is this acid. Right?

[00:11:29]This is its acid. Now if it is amide, i.e. add isostere of OH.

[00:11:34]What has this become? became an amide. Right?

[00:11:36]So what happened? The acid became amide. Isn't it? This became amide. So what is this even?

[00:11:41]Its bioster is done. Ok? Sulfonic acid. SO3H, right? SO3H like this is this what is this?

[00:11:51]Sulfonic acid group. Sir what even is sulfonic acid? This is your analog of this. So this is also your bioster. So all of the above is the correct answer. Ok? Option D will be corrected. All of the above. It is also sulfonic acid, it is also amide, tetrazole is a non-classical biosynthetic. Please remember this.

[00:12:08]Non-classical means their shape and size are not the same. are also not isoelectronic. But pharmacological action means SD character shows this. Isn't it? By which activity was denoted. Like now we see all this in antifungals.

[00:12:25]You will get to see it in many places.

[00:12:30]So this is your D option. Ok?

[00:12:34]Tetrazoles, acids, amides and sulfonic acids, what are all these to you? There are bioisosteres. Which of the following groups is not usually used during the cad?

[00:12:47]What do we not use usefully in CAD, i.e. Computer Aided Drug Design? So we do molecular modeling anyway.

[00:12:51]Ok? Molecular design is also done. Rational drug designing also takes place. There is no concept of organic reaction in this.

[00:13:02]So what happened to option D? It got corrected. What happened to option D? It got corrected. So CAD molecular molding CAMD is computer aided molecular design, right? So this is your rational drug design which is visible in it. The organic reaction is not directly involved here.

[00:13:25]Which drug is not prepared by computer and a drug design CAD.

[00:13:28]So drug means its derivative, here drug derivative has been talked about. Ok? So borinen borpinus ajocin ajonin. Ok?

[00:13:42]So what is seen here is that the boring pin is not duck designing based. Duck is not designing based.

[00:13:52]So what happened to Boripin? It got corrected.

[00:13:55]This question had come in 2018.

[00:13:59]So boripin is a boron containing seven membered ring and it is not commonly associated with the drug development. Yes, so this question of yours has been raised from here. The rest of the azosine derivatives that the drug is yours was designed. Like there is benzozesine, this is benzosine, this is yours, this developed azosine is designed in anti cancer, so all these of yours have been optimized but borepin has not been observed in case of duck designing. Ok? Let's come now, there is COMFA, COMFESIA, COMFESIA, this COMFESIA will be COMFESIA, okay, so what is your COMFA and COMFESIA related to, from 2D QSR, from 3D QSR, from molecular docking or all of the above, COFA and COMFESIA is comparative molecular field analysis, and COMFESIA measures surface indices. So what is here is related to 3D QSR. Ok? 3D QSR so what will happen here? Option B will be corrected. What will be option B? It will be corrected. So, what are your Komfa and Komphasia related to? 3D is related to QSR. Ok?

[00:15:25]What is the P in QSR? P denotes what is in QSR. So what does the P symbol stand for? What symbol does P denote? Isn't it the partition coefficient polarity pro drug pA, so none of these is correct, what does p denote partition coefficient because partition coefficient is such a parameter of the drug that on enhancement the parameter will get enhanced, if pA gets enhanced then hydrophobicity right which we call lipophilic will increase, okay it will increase, so partition coefficient plays a very important role in QSR equation.

[00:16:03]From this we find out whether the biological activity will increase or decrease. So your partition coefficient denotes this. Ok? This is P, right? So how is the partition coefficient calculated? Lipophycy and hydrophicity denote it. It tells its relation.

[00:16:21]So we find this out from the ratio of your canal and water.

[00:16:25]Ok?

[00:16:28]Let's see, in Kasr modeling, the predictor consists of, isn't it? What is the predictor in Kasr model?

[00:16:34]Physicochemical properties, yes, theoretical molecular descriptor of the chemical, it is definitely both A and B.

[00:16:43]Pharmaceutical properties, this is not there, this is your correct, both the options are visible in it, both A and B. So this was asked in 2018, okay, it was asked in 2018, so let's talk about physicochemical property i.e. descriptor. Like which of yours is hydrophobic ah along with which is Hans pi value and was electronic descriptor. was the steric descriptor.

[00:17:09]So what is all this?

[00:17:11]Denotes physicochemical properties. And theoretical molecular descriptors mean topological ones like topological indices, geometrical descriptors, quantum chemical parameters, electronics properties, all these are based on modern methods. So, compute computational method is topological, which means ah, tropical surface, which means the arrangement of atoms, 1 2 3 atoms, we do numbering, so what is the orientation of carbon, what is its shape?

[00:17:42]What is the shape of the remaining number of carbons or what is the shape of the group? Is it affecting biological activity in any way? So those topics come under topological indices. Ok? So this is your advance, we measure bond angle, bond length etc. in this. It 's a Tojan angle, right? Let's study QSR. R is the terms related to R in QSR.

[00:18:05]When generating the QSR equation, some statistical data comes into it. Ok? So an R value is also denoted in it.

[00:18:13]So what is that R called?

[00:18:16]What does it denote? This has been asked.

[00:18:18]Ok? In 2018, we denote hydrophobicity by pi, right?

[00:18:23]Hammett's constant is denoted by sigma.

[00:18:25]Correlation coefficient, yes, this is r, right, and regression coefficient, what is this to you? r and this r² are regression coefficient and correlation coefficient, these are two things.

[00:18:40]So what's up with you? If we talk about regression here, you get r² and what is the correlation coefficient? It becomes r.

[00:18:50]So r and r² are the two terms we see here.

[00:18:52]So what does r denote?

[00:18:57]denotes the correlation coefficient. So like we write equations, biological activity, right? When biological activity is denoted, there is a constant. Right? It is constant.

[00:19:08]So whatever value is written here, whatever is the constant, suppose that and this is log p plus whatever is your second parameter, then the coefficient which is denoted here, we call it correlation coefficient, so what is this percentage, like the value of 8r is 85, right, so 85%, it is correlating with the biological activity, with the parameter, so this denotes your r correlation coefficient n here and the regression coefficient which is your r square or particular constant which is denoted, this is also denoted there.

[00:19:49]Let's see what QSR is related to? Who is it related to? Sodinger Equation Molecular Geometry Structure Modification of Drug Field Chemistry. So what is QSR? Structural modification of drug here. When any drug is modified, any structure is modified, then what changes occur in its biological activity? Right?

[00:20:14]So what is here will denote the modification of the drug.

[00:20:17]So what is QSR? Option C will be corrected. Isn't it? Quantity Structure Activity Relationship So we study QSR equation. So what is here denotes this particular modification.

[00:20:32]Right? So, we will study through QSR which descriptors are affecting the biological activity.

[00:20:42]Crack Plot Use Drug Designing, Protein Structure Determination, Nucleic Acid Structure Determination, Carbohydrate Structure Determination. Ok? So why did the crack plot come about? The crack plot is seen in your drug designing case. It is available in the case of drug designing, right? Your Crook plot is in different coordinates, here the different parameters mean like pi or sigma, they had represented its descriptor, so here it became positive minus, here minus became minus, here your minus became positive, in this way they had divided the coordinate, so Crook is used in blood drug designing, okay here hydrophobicity means pi and electronic property means sigma, they had done the Crook plot between these parameters.

[00:21:32]Ok? So we use it in Dagani. Which of the following software is used for the conversion of 2D structure to 3D structure? Yes to D to 3D structure this is yours in 208.

[00:21:44]Korina Omega Oompha J Doc. Ok? So all this is used for docking. This is for 3D QSR. This is your specific symbol. The Corona here is 3D, right? Korina which is 2D to 3D is denoted. Isn't it? Present is used to change 2D to 3D. So if you want to create a high quality 3D structure from 2D, then you can use Korina.

[00:22:11]Korina is a software program that can convert 2D to 3D.

[00:22:16]So you can use smiles here or you can create it using the SD file.

[00:22:21]Ok? Here again came Kofa and Comfessia. Kofa Comfesia R The Software That R Used.

[00:22:30]What is this software actually? There are programs. What is this Kumfa Kofesia? It is a kind of program. And what do we use this for? 2D Structure of Molecules. 3D Structure of Molecules. Molecular docking, molecular weights. Isn't it? Who will this Kumfa be for? 3D for QSR. For whom? 3D Structure of Molecules. So when we do 3D QSR, it gives you field analysis done in Kumfa. By comparing it, we find out the orientation of the structure of the new molecules.

[00:23:03]Ok? So you will see all these questions in your nipper finger trip.

[00:23:08]3D QHR so 3D QSR is your comparative molecular field analysis and Compassium is the comparative molecular similarity indices analysis. It is Compesia. This is what you get for 3D QSR.

[00:23:24]Nifedipine This is a ring based question.

[00:23:26]Nifedipine nitro is directly attached to phenyl.

[00:23:29]And Deepin means Pirin.

[00:23:33]So what is the pyridine here? There is no pyrol, no pyridine, no parazine.

[00:23:37]One for dihydropyridine derivatives. So what is option D? This will be corrected.

[00:23:43]Option D will be corrected. One for dihydropyridine. So this is a cancel blocker drug.

[00:23:48]Lipidpin, if we talk about your one four dihydropyridine, then hydrogen is attached on one and four. This is the pyridine ring. This question was asked to you from here.

[00:24:02]This question has come in Sniper 208. What are you saying?

[00:24:04]Which software does not work on the principle of docking? Which one will make docking not work? So is Trip Doc. This can be used by you. There's Concord, there's Lip Dock, there's Ligand Fit. Ok? So this is your Legend Fit Cockard, these are different types of software. Isn't it? So which ligands fit, right? That is what you can see with your concord. In which your docking does not happen. Ok?

[00:24:36]So cockard and ligand fit here. So what do we do at Legged Fit? Get the legged fitted. Get it docked.

[00:24:43]So this can be used for docking. This is also used in docking and this is also used. But we don't use this.

[00:24:50]So what will happen?

[00:24:55]What is a cockard? This is a subject verb. There is no specific software that is used here. Actually. So this is your question which has been asked from here.

[00:25:07]Ok?

[00:25:09]What did I tell you about this Biga Bat Trin B?

[00:25:11]I apply vinyl to you. GABA Gambaateric acid Trin means transaminase inhibitors. That is why this GABA Biga B Gabatrin is called, it is an anti-epileptic drug, anti-anemic drug, all these can be used, so phenyl ring derivative, benzyl ring derivative, acyclic carboxylic acid derivative, amide derivative, so acyclic carboxylic acid derivative is seen. This is a Biga battery, if you see the structure then see here it is written Bi, what happened to Bi, what happened to Bi, what is vinyl attached here, vinyl is attached here, hence B is gamma, so alpha beta and gamma, so gamma amino butyric acid GABA and this is a transaminase inhibitor. Isn't it? Inhibits trans amino enzymes.

[00:26:04]So this is your trin, it can correlate it to the mechanism of the drug as well as its structure. Isn't it?

[00:26:13]If morphine is heated with the concentrated HCL, what will be formed? This question was asked in Sniper JE 2007. So what will happen here? Apomorphine, ethyl morphine, isopropoxymorphine, none of the above. So apomorphine is formed.

[00:26:31]Ok? Apomorphine will be formed.

[00:26:34]What is option A here? It will be corrected.

[00:26:38]Option A will be corrected. So this is your 25% HCL, right? And what was this Totally Ring of yours? It has been converted. It is fused with piperine.

[00:26:53]And here we will see two hydroxy groups.

[00:26:56]So this is your apomophine.

[00:27:01]What category does Olanzapine fall into? Ok? So these are new typical antipsychotics, older typical antipsychotics, new atypical antipsychotics, acyclic, older typical antipsychotics, acyclic. So what?

[00:27:15]This was an anti-neurological type drug. Your typical one comes under atypical. A typical and typical.

[00:27:23]Ok? So this is typical and the category that has been kept for you is that it will come in A typical here, this is fine, it will come in A typical with antipsychotic single, so what happened to you, C option will be correct, okay, C option is simply what it is, it is a question from classification, so it is a pharmacology based question, there is no chemistry in it, but here it is directly asked from the classification that which drug is A typical neuroleptic, so Olenza papin was talked about, so this of yours will be corrected here.

[00:27:59]Azeridine moiety is present in which of the following drug Azeridine means this ring will be present in which? In which drug will it be seen? So dacarbazine hydrazine cyclo phosphamide mitomycin C lomustine mitroso urea so what is your mitomycin? Mitomycin is a derivative of? This is yours Erardin will get to see. So this question has come up in 2017 also.

[00:28:30]Ring based questions, you must have done ring based questions in the jeep.

[00:28:35]You will be able to answer all the questions. Okay, right? So how many times did we practice mitomycin? So if we look at Dacarbazine here, it is a triazine derivative and Da is imidazole. There's imidazole here.

[00:28:52]Cyclo phosphamide is your alkylating agents mitomycin that's what azadine is. Ok? This is what your Azerdin will see.

[00:29:02]Right? And lomustine which is a nitroso urea derivative. Nitroso urea derivative. So this is your macrocyclic ring present in V structure, so macrocyclic does not mean micro, microcyclic means large structure.

[00:29:19]Ok? There is no penicillin. Isn't it? Reformsin yes this is Reformsin the structure of Reformsin is large. It is of Mac size. Isonon is an aged small molecule. Tetracyclic is also not very large. Ok? Reformsin is a very large structure. It is macrocyclic.

[00:29:38]Ok? So what will be option B? It will be corrected. This is the structure of reforms. What a huge structure it is with the cyclic. Right? Here's what we have with piperazine. So this is your naphthalene with the central ring right here.

[00:29:52]So this is what you have been asked here, why was Reforms in RIRI written?

[00:29:58]Because R means RNA inverters RI, what do you have to correlate with Ri?

[00:30:04]It invites RNA to RNA inviters.

[00:30:07]Right? Lipski's Rule of Five. Yes, medicinal chemistry has a very important role.

[00:30:12]Does not include V of the following molecular weight less than 500 yes he included log also should be less than five number of rotational bonds less than 10 this is not what he talked about donor less than five so this your C is not related to it, it is not related to C right so what happened your C will be corrected so this will be seen in your JDC nipper finger tip is C option right this this rotatable bond which was talked about is Waivers rules it was taken from here it is not Nipshki rules which drug this strategy involves replacing the functional group with the similar one right similar one so similar one is any functional group it should be replaced with its isostere means similar to that whose shape and size is isoelectric and it is replaced then what will you call that process? Where did you study lead optimization, bioisosterism, pro drug desiring, fragmentation?

[00:31:23]In mass spectroscopy. So what 's in here? It is called a bioisostere. Bio isostries or isostries that occur.

[00:31:30]So when the same biological activity continues, when the group is replaced, what do we call it? Bio isostories that is. Ok? So this is of yours, like biosters, it is of carboxylic group. Isn't it? Non-classical tetrazoles are made by replacing them.

[00:31:51]Which is a common software right common software used for 3D molecular visualization. If you want to visualize 3D molecules, which software will you use? So what is there here? Pamol. Yes, it is very important and common, we do not see all this in Excel, Word, PowerPoint, where will we see it, in Primer, okay, similarly there is Drug Discovery Studio, okay, you can see the molecules through Discovery Studio also, okay, so this option is correct, here the mall is your shortchanger, right, this is open source molecule visualization for visualization, so you can do this also for micro molecules, proteins, nucleic acids.

[00:32:38]Right? Let's see, sulfonamides are structurally and chemically related to what? So, the structure and chemicals of sulfonamides are related to what? Right? So if we talk about sulfonamide here, then the sulfonamide that is there is from sulfonamide. Right? Isn't it? That's your sulfonamides. Now what is GABA GABA amino butyric acid PABA para amino benzoic acid is CABA LABA, so the para amino benzoic acid which you have is amino benzoic acid right so sulfonamides if this is like this here there are sulfonamides in the same way let's talk about benzoic acid gamma this para amino benzoic acid right this is also NH2 so what are these two? Its analogue is. So it became an analogue of PABA. What will be option B? It will be corrected. So this is your question, its analog has been asked. Papa right? So this is your para amino benzoic, these are sulfonamides and para amino benzoic acids which are its analogs. Ok? So these are some important questions related to Sniper which were asked in previous years. Ok? And you should practice this. Maybe this will lead to some question related to this, right? Because he gets some new questions similar to his own. But there is no exact question, but indirect questions are found. Ok? So these are some important questions for your sniper. Ok? Okay, okay? Thank you, thank you very much.