Skeletal muscle is the primary site of glucose disposal in the body and serves as the mechanism that makes insulin work effectively; without sufficient lean muscle mass, individuals develop insulin resistance regardless of their body weight, which explains why thin people can also develop diabetes and why weight loss through GLP-1s often leads to a metabolic wall when muscle is lost alongside fat.
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The best method to improve insulin sensitivity...Added:
The best protocol for insulin resistance is not a peptide. Most people never hear this from their doctors, and I'm going to tell you exactly what it is. I'm Dr. Adrienne Towsen. I spent 21 years as an orthopedic surgeon watching what happens when people ignore this protocol. Right now, everyone wants the same thing. Fix the metabolism, drop the visceral fat, get the blood sugar under control.
Peptides, GLP-1s, IV drips, that's all that you hear about. And these are real tools, and some of them work extremely well. But, there's one variable that determines whether any of them hold long-term. And almost nobody addresses it, or at least they don't address it in the way that they should. And it's muscle, skeletal muscle. That's the primary site of glucose disposal in your body. It's the mechanism which makes insulin work. If you don't have enough lean muscle mass, you have insulin resistance regardless of what you weigh.
So, that's why thin people can also develop diabetes. That's why people lose weight on GLP-1s and then hit a wall because they lost fat and muscle at the same time. The insulin resistance comes back because the foundation wasn't there.
So, I use peptide protocols, hormone protocols every day in my clinic. The patients who get the best long-term results, though, pair them with a serious resistance training program. The two together produce outcomes that neither one can really produce alone. 30 minutes of resistance training, ideally three times a week, starts shifting this outcome. Everything I prescribe works better when the muscle foundation is there. Most patients will come in certainly asking about peptides, asking about hormone therapy, GLP-1s before they've addressed this. We always start the consultation with going right back to the foundation. Let's talk about your nutrition. Let's talk about exercise and strength training. So, has your doc talked to you about this? Drop it in the comments.
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