Can AI unlock the cure for genetic diseases? 🧬

Added: 2026-05-17

[00:00:00]Oh, one of my favorites also is Alpha Genome.

[00:00:03]>> Yes. So, I reached out to yet another Nobel Prize winner, [laughter] Dr. Jennifer Doudna, who I've had on the show.

[00:00:10]>> And she sent a question for you. So, I'm going to read this question from Dr. Doudna.

[00:00:14]>> Okay. So, she says, "CRISPR, the gene editing technology that she pioneered, can now target nearly any DNA sequence.

[00:00:22]But for most genetic diseases, we still don't fully understand which changes in the DNA are actually driving the problem, especially in the 98% of the genome that doesn't code for proteins.

[00:00:32]With tools like Alpha Genome starting to decode that 98%, how close do you think we are to the moment where AI can reliably point to the exact genetic change causing a patient's disease, so that technologies like CRISPR can fix it?"

[00:00:45]>> Yeah, what an awesome question. You know, I've discussed this with her actually in the past and and it is really exciting. I think with Alpha Genome, which is exactly that kind of technology, it takes the big long genetic sequences and then it tries to predict the