Rapid responders to GLP-1 weight loss medications like Wegovy typically have higher GLP-1 sensitivity driven by genetics and physiology, are more commonly female, younger, have higher fat and muscle mass, and do not have diabetes; however, slow responders can achieve similar weight loss outcomes with time and consistency, as individual response rates vary like a thermostat's temperature sensitivity.
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Deep Dive
Rapid vs slow responders #Wegovy #GLP1 #WeightLossAdded:
Why do some people lose weight fast and others take longer but still win? What we're finding is that rapid responders tend to cluster in certain patterns.
They already out the gate have a higher GLP-1 sensitivity, which is likely going to be driven by their genetics and own personal physiology. They more commonly are female, younger, have a higher level of fat mass and muscle mass to begin with, and they also tend to not have diabetes. That's the general profile for a rapid responder that we have at this point in time. And if you think of it kind of like a thermostat, there's some people that are going to notice a change in temperature almost immediately, whereas other people, it's going to be slower and more gradual and take some time for them to notice that change. But here's what matters for those more slow responders. With time and consistency, they can achieve very similar outcomes.
And once you understand what's actually driving that difference, you'll know what exactly to focus on to help your journey along the way.
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