Introducing Prequel's NEW Anti-Itch Solution Medicated Calming Lotion | Dr. Sam Ellis

Added: 2026-05-28

[00:00:00]Itch is one of the most underestimated skin symptoms, but one of the most challenging for patients to live with, which is why I'm so excited that Prequel is launching our new anti-itch solution medicated calming lotion.

[00:00:15]Being a dermatologist means helping others even with the not-so-glamorous skin concerns, and one of the biggest ones is itchy skin. Pruritus is the medical term for itch, and it can have so many causes: [music] allergic reactions, irritated skin, eczema, dryness, even hormonal changes. The list goes on, and when your skin is itchy, what you really [music] want is fast relief. With this new anti-itch solution, my goal was to help relieve the [music] itch associated with minor skin irritation, while still making a lotion you actually want to use. So many patients in my clinic, and honestly, so many of you guys in my DMs tell me [music] how much itch impacts your day-to-day life or the life of your loved one. It's uncomfortable, it's distracting, and it can be really frustrating. And as tempting as scratching feels in [music] the moment, it can actually make things a lot worse.

[00:01:02]It increases inflammation, it breaks down your [music] skin barrier, and it can lead to things like infection and scars. I have always known that if I was going to build Prequel the right way, coming at skincare from the point of view of a dermatologist who treats thousands of patients a year, we would need elevated solutions to treat itchy skin. And every Prequel product is designed to be [music] effective, but also thoughtful and modern. Our anti-itch solution medicated calming lotion is formulated with 1% [music] pramoxine hydrochloride. Pramoxine hydrochloride is a very well-established anti-itch ingredient within dermatology.

[00:01:34]It's non-steroidal, and it's an external anesthetic, meaning that it works by temporarily numbing the nerve endings [music] in the skin. The way I explain it to patients is it interrupts the nerve signal before it reaches your brain. And it's widely used to relieve itch associated with eczema-prone skin, contact dermatitis, insect bites, rashes, minor burns, or skin irritation, [music] or anyone with just dry sensitive skin.

[00:01:56]To truly elevate this formula, we added one of my favorite skin care technologies, something you may recognize from prequel's redness reform serum. [music] We call them our soothing molecules and this technology delivers a high concentration of avenanthramides, which are the key soothing [music] compounds found in oat. So, you're getting both immediate itch relief from pramoxine and longer lasting comfort and calming from those soothing molecules.

[00:02:19]This is not your average drugstore anti-itch lotion. Also, when skin is itchy, supporting the skin barrier is critical. Anytime you have a breakdown in your skin barrier, it allows external elements to get into the skin and cause more problems. So, a great anti-itch product should not only have anti-itch ingredients, but also things that target the skin barrier and help balance and support [music] it. And that's why this formula also includes allantoin to moisturize and soothe, a multi-ceramide blend to support barrier function and [music] hydration, and dimethicone to smooth skin and optimize the texture of the lotion. Everything in here is designed to [music] calm, comfort, and protect itchy or compromised skin. And when it comes to texture, you know my philosophy with prequel is basic plus.

[00:03:01]Utilitarian, solution-focused [music] products that you actually look forward to putting on your skin. If you're familiar with the prequel moisturizer portfolio, this lotion is a little more substantial than the urea moisturizing milk, but not as thick as the barrier therapy cream. On the skin, it feels silky and nourishing. It glides on effortlessly, absorbs well, and leaves a very natural finish. It's not shiny, not dewy, and certainly not sticky or tacky.

[00:03:26]When your skin is itchy, you want comfort but not heaviness and I feel like this lotion strikes that balance perfectly. Now, in terms of how to use this, if your skin just feels dry or a little barrier impaired, I would reach for our barrier therapy cream. However, if your skin is itchy or you have that uncomfortable awareness of your skin, this would be my go-to for immediate itch relief. I think of anti-itch solution almost like a first-aid lotion if you have bug bites, random, itchy patches, or any flare-up [music] that just needs calming now. And I am so excited to have this clinically tested option for both my adult and pediatric [music] eczema patients. Our anti-itch solution medicated calming lotion is non-greasy, [music] fragrance-free, hypoallergenic, allergy-tested, steroid-free, and suitable for all skin types, including those with sensitive and eczema-prone skin. If itchy skin is something you deal with even occasionally, I truly think you will love this lotion. To me, this is exactly how medicated skin care should feel, effective, comforting, and thoughtfully made. Prequel's anti-itch solution medicated calming lotion is now available at prequelskin.com. As always, do not hesitate to reach out with any questions, and don't forget to follow us at Prequel Skin.

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