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Do GLP-1's fix insulin resistance or metabolic disease? 📱
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141 views15likes43:53healthycarnivoreOriginal Release: 2026-05-12

GLP-1 medications (such as Ozempic and Wegovy) provide temporary benefits for appetite suppression and short-term improvement in metabolic markers like hemoglobin A1C and fasting glucose, but they do not address the root causes of metabolic disease including mitochondrial dysfunction, muscle insulin resistance, or hyperinsulinemia. Long-term use leads to significant muscle and bone loss (up to 40% each), with bone loss being particularly concerning as it is difficult to reverse, especially after age 50. When discontinued, patients typically experience rapid weight regain (50-80% within the first year) and return to previous metabolic states. The medications are not recommended for children due to risks of impaired growth, delayed puberty, hormonal disruption, and altered leptin signaling.

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