A brilliant masterclass in molecular hacking that treats the immune system like a firewall to be bypassed. Itโs the ultimate "stealth mode" for medicine, turning complex biology into a programmable game of hide-and-seek.
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This Tiny Vessel Could Outsmart Your Immune System ๐งฌ #shorts่ฟฝๅ :
If this protein shell gets rejected, the patient dies. For decades, allergenic cell therapy using donor cells as medicine kept hitting the same wall. The immune system destroys them on contact.
A team at the Pollson lab, UC San Diego, used cheoenzyatic cascades, basically enzyatic assembly lines, to rewrite the sugar coat on extracellular vesicles. If this scales, donor cell therapies could become programmable surfaces tuned to evade rejection, like changing a lock midflight. Single preclinical paper so far.
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