Can weight loss drugs make you fall OUT of love?

Added: 2026-05-18

[00:00:00]Thousands of people on GLP-1 weight loss medications like OMIC and Wiggovi are reporting something that their doctors never mentioned as a side effect. Their relationships are totally changing and not in the ways that were expected.

[00:00:13]Three things. Number one, several users report losing interest in activities, foods, and even people they previously found deeply pleasurable. The drugs quiet the brain's reward system broadly, not just around food. Number two, therapists are reporting an uptick in couples where one partner on a weight loss drug has become emotionally flatter, much less engaged, and in some cases less romantically interested. The partner often on the medication, not on the medication, often describes feeling like they're living with someone totally different. Number three, researchers studying GLP-1 receptors in the brain found they are present in areas governing emotional attachment, motivation, and bonding, not just appetite. The drug may literally be changing the number on the scale and also the person attached to it at the same time. Of course, talk to your doctor before assuming this flatness is depression. The case, the cause may be biochemical and specific, but follow along for more and share this with someone out there who's navigating this quietly.