In managing Multiple Sclerosis, healthcare providers balance the safety of immunosuppressive medications by monitoring laboratory markers like IgG and ALC levels to ensure patients maintain adequate immune function and reduced infection risk, while simultaneously assessing disease control through CD19 counts, inflammation markers (such as the Octave test), MRI imaging, and clinical experience to determine optimal medication redosing timing.
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Deep Dive
Balancing safety of medicine and benefit of controlling MSAdded:
So, when you start to think about this, we're really balancing two things. We're balancing the safety of the medicine by checking laboratories like the IgG and the ALC to make sure that they're high enough that you're not at increased risk for infection.
And we're balancing that risk with the benefit of controlling the disease.
We're looking at things like the CD19 count to see if we need to redose. And measures of inflammation like the Octave test, the MRI, or your clinical experience. That's the risk benefit that we're applying when trying to figure out if it's time to redose your medicine.
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