McFall’s engineering approach brings much-needed clarity to the chaotic peptide market by prioritizing proven human data over speculative hype. It is a masterclass in applying systematic ROI analysis to the complexities of biological optimization.
Deep Dive
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Deep Dive
After Testing Everything, This is All I Take!
Added:I've spent thousands on hormones and peptides. And if I lost everything tomorrow and had to rebuild my physique from scratch, I wouldn't buy most of it again. In fact, if someone handed me the entire available list of peptides for free, most of them would end up in the trash. Because after years of experimenting, I've learned something.
The fitness industry doesn't make money by telling you what actually works. It makes money by convincing you you need more and more things. More peptides, more stacks, more injections, more complexity. But physique transformation follows the rule of diminishing returns.
And few things even move the needle. And some things are so expensive, inconvenient, or the results are so uncertain that they're simply not worth doing. So in this video, I'm just going to show you exactly what I take, what I pay for it, and why I take it. This isn't medical advice. This is simply me telling you what I'm doing after experimenting on myself. And we're going to rank everything based on one thing, return on investment. Not hype, not marketing, not bro science, ROI. I'm Tory McFall. I'm an engineer who separates signal from influencer noise and reduces physique transformation to the few decisions that actually move the needle.
This video is going to move fast and it's going to unveil a chart that captures my exact decision matrix for the stack I use to stay ripped at 47. If you want your own copy, sign up for my weekly newsletter, The Signal. It's awesome and it's free. The link's in the description. So let's start at the very top of the ROI ladder. Nothing else in this video comes close to testosterone.
If you're a man with low T, there's no peptide on this earth that can compete with getting your testosterone optimized. They can't compete in terms of muscle, recovery, libido, energy, fat loss, quality of life, nothing. If I had to choose between every peptide in this pile or properly dosed TRT, it's TRT every time. The ROI is absolutely insane, and that's great because it eliminates a lot of noise right off the bat. If you've been spending months looking at what peptides might do for you and you haven't looked at your testosterone levels, do that first. If you're on the fence about TRT, then watch this video.
Now, most people assume that the most efficient use of your money if you're already on TRT is to just push up your testosterone dose.
I don't. When I want additional anabolic support, which for me is usually only in a cut, I prefer low doses of mild compounds like Primobolan, nandrolone, and Anavar because this allows me to dial up the anabolic effect and more importantly the anti-catabolic effect while cutting without just driving up the testosterone that comes with all the androgenic baggage, back hair, and acne, and estrogen conversion. I hate the thought of losing muscle when I'm cutting after taking years of slowly gaining muscle on just TRT, proper training, and diet.
So, the risk to reward for me of taking lower doses of milder anabolics, especially the return on the cost of those, makes sense for me when I want to be in an aggressive calorie deficit and use those for a short period of time. I also keep very low dose nandrolone in my cycle because I feel like it helps me with joint comfort. And at 47, that sometimes becomes the bottleneck. Do these come with risk? Absolutely. That's why I keep the doses low. But, from a physique ROI standpoint, they are dramatically more effective than most peptides that people obsess over.
If you're interested in what my low-dose cycles look like, watch this video. Next up is human growth hormone. Now we're entering the first area where I think the peptide industry has completely lost the plot. If I'm trying to choose between human growth hormone itself or growth hormone peptides, secretagogues, I'm choosing HGH every time.
The hype around having natural GH pulsatility is wildly overrated in my opinion.
If you watch a ton of these videos, you may even believe that that pulsatility somehow makes them magic or superior to growth hormone. And while the research that I've read has led me to believe that pulsatility might have a boosting effect to eliminating fat and visceral fat included, at the end of the day, the strongest correlation is going to be between growth hormone total exposure and fat loss. And HGH allows you to dial that in directly. The natural pulsatility obsession comes in probably most when people are talking about uh tesamorelin.
People hear about the studies where tesamorelin destroys visceral fat, and they assume that there's something magical about tesamorelin. But at the end of the day, it's just producing powerful GH pulses. The fat loss effects are downstream of GH, and GH is driving that impact. It's just that tesamorelin was specifically studied to look at its impact on visceral fat. So why isn't everyone just taking HGH? It's because it's really expensive. Uh to take it through a clinic, it's very cost-prohibitive. So I source mine differently.
Could it be fake? Sure. But I can tell you this, I've got the habit of biting my nails.
Gross, I know.
But recently I was biting my nails and realized I was having trouble getting through them. And that was after being on the growth hormone that I purchased for only a few weeks. I also started experiencing some hand numbness, which is a common side effect when growth hormone is too high.
So, I dialed that dose down. But, ultimately that let me know that something was happening and it was consistent with being HGH. And honestly, you don't know that the gray market peptides you're getting are what they say they are, that they're dosed properly, either. So, that's my decision. The biggest consequence of it is that I get to eliminate an enormous swath of the popular peptides that are out now, all those growth hormone secretagogues. So, if you want to get into the weeds about how growth hormone actually stacks up against all those secretagogues, watch this video.
So, let's talk about retatrutide. This is the first peptide where I stop arguing and I just say yes. Retatrutide is worth it. Not because it's magic, but because it solves one of the hardest parts of getting lean, dieting. Food noise disappears. And when you're dieting hard and trying to get lean, that's a superpower. You formulate your ideal diet and then your cravings are not fighting you on it.
Everything else I see is just a bonus.
The improved insulin sensitivity, bonus.
The nutrient partitioning, bonus. The metabolic effects, bonus. And it's cost-effective. It's not that expensive and what I'm paying for is making adherence to my diet nearly effortless.
It's especially cost-effective for me because I find that I can't go much higher than 1 mg per week before my appetite's so suppressed, I can't even get up to things like a 750 calorie deficit. Retatrutide is one of the few peptides where I don't feel like I'm squinting at rodent data and hoping that it translates to humans.
The human data is real, fat loss, blood sugar improvement, liver fat reduction, better cardio-metabolic markers.
I'm not ready to call it an anti-aging drug like a lot of people are, but if aging is accelerated by visceral fat, fatty liver, insulin resistance, and poor metabolic health, then Retatide may be one of the most powerful anti-aging adjacent compounds in the entire stack.
And for me, this just creates one of the highest ROI profiles in this entire video. And honestly, if we stopped right here, this is where ROI is probably maxed out. TRT, mild anabolics, you know, usually in a a cut is where I think they're used best.
Um human growth hormone, and Retatide for dieting. This is the stack that delivers the overwhelming majority of my results. And if you notice up to this point, and you look at the chart and the pinning frequency, I'm not a human pin cushion at this point, either. Money has been spent effectively up to this point. So, now we're going to turn to where things get a little more complicated, because this is where the benefits get smaller, and the evidence gets weaker, and the injection burden on many of these climb significantly. So, as I evaluate these remaining peptides, I'm looking at number one, what's the promised benefit? Number two, how likely is the animal data to transfer to humans? And number three, is it worth the money and the injection burden? So, for that second question, it's important to know where rat studies tend to translate to humans and where they don't. So, when it comes to hormones and metabolism and appetite regulation, we actually see it usually does transfer from the rats to humans. When it comes to muscle growth, the translation I would rate as mid. When it comes to injury healing, the translation is mid to low. And when it comes to longevity, that's been pretty disappointing in the past that we find these things that increase longevity in mice and it just doesn't translate over to humans very well. So, let's talk about MOTS-c and NAD+. No doubt these are fascinating compounds and the animal data is genuinely interesting. Better metabolism, improved exercise performance, potential mitochondrial benefits, healthy aging possibilities.
But here's my problem. The human data simply isn't strong enough yet. So, in terms of anti-aging abilities that these things have, we know that that translates weakly.
Uh as far as the metabolic and mitochondrial health, that translates much better. But as of right now, the human data is so limited that there's just not room for me to have much confidence in the magnitude of the benefit. Could they work? Absolutely.
Could they eventually become staples?
Sure, maybe. But when I compare the certainty of benefit of things like TRT, HGH, retatrutide to these, they're not in the same universe. And when I look at the cost, it pushes me away from them even more.
Now, if you're older and you know that some of these things are degrading for you and these offer promise and you have a lot of disposable income, get maybe you give them a go. Um you know, maybe it's worth it to you. But for me, as of right now, they're in the interesting but not essential category.
Then we have the healing peptides, your BPC-157s, TB-500s, your uh you know, together the Wolverine stack or the glow stack or the close stack. Uh I've tried them and honestly, [clears throat] I didn't see a major benefit. Now, maybe it's because I didn't take them in a high enough dosage, maybe I didn't take them for long enough, but you know, I've had people who have reported that it's helped them with injuries, but these are younger people and they may have healed in that amount of time anyway. I can say as an older guy with some nagging injuries, things like uh greater trochanter hip pain, uh that shouldn't go away for months and months, um you know, or little nagging things in the shoulder or the forearms, this stuff is like uh when it's tendon-related, I just I can just speak for me and say that it it didn't heal me. And I've gotten better over avoiding things that hurt it, and those injuries still haven't gone away. And I took the Wolverine stack and I took the Glow stack for several months. And that's a difficult thing for me to say because I I really wanted them to work. That's sometimes the biggest bottleneck for me. So, you know, I paid for them, I pinned them, I took that time. They They just didn't have the results that I hoped they would. Now, with the Glow stack, there's a possibility my skin improved. My uh fiance was making some comments about that. But, I was also, you know, I'd started the human growth hormone not too long before that, so it's hard to know how much of that was due to uh the growth hormone and how much of it may have been due to that Glow stack or just the component um the GHK copper component alone. So, in the future, I think um I might look at the GHK copper uh without the BPC-157 and TB-500. And you know, that brings up a good point because if you can source affordable growth hormone, and it's carrying the load of a lot of these peptides, then it eliminates, you know, the need to be redundant in the uncertain areas or where things are are getting expensive.
There's also a cautionary tale for buying these things together uh in the stacks. The glows, the clothes, the Wolverine stacks, there is some research now saying that they can lose up to 60% of their efficacy by being mixed together in the same vial. So, my suggestion is even if you did want to take them all to buy them separately, you can still draw them into the same syringe in that moment that they're together in the syringe for a single injection is not likely to be long enough for them to degrade like they would be combined in the same vial. Also, when they all come mixed together, you lose the ability to adjust the individual dosing of each of the components. You know, what we started talking about GHK copper and you know, I think that one's worth mentioning even though it's not technically a physique compound unless you consider your skin health, your skin appearance to be part of your physique, which I suppose that I you know, that it is, especially you know, when some of these compounds can make your skin look worse. I like the idea of it.
There's quite a bit of evidence behind this one that it works. It's not that expensive.
So, this is actually one that I'll probably, even though I'm not calling this one essential or anything by any means, one that I will probably include in my stack for a while just to see if I can notice positive changes in my skin appearance. So, if I lost everything tomorrow and had to start over, my shopping list would be surprisingly short. TRT, retatrutide, human growth hormone, and a few carefully chosen anabolics.
I'd save the rest of my money for things like food, training, sleep, and blood work. Cuz after years of training, I can say confidently that's where the real results come from.
And so, here's the whole chart and how everything we talked about can be compared. I'm going to leave it here for you to look at it for a minute, but remember if if this is an eye chart and you can't see it on your device that you're watching this on, don't forget that if you just sign up for the signal, my free newsletter, the link is in the description, you'll get this access to this and all my past episodes as well and I tend to do a lot of charts and things like this that make little menus that make it easy for you to make decisions.
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