The video cleverly dresses up basic nutritional advice in "bio-hacking" jargon to offer a simplistic solution for a complex environmental problem. While the science behind the ingredients is real, promising a one-week detox for microplastics is more marketing than medicine.
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This Detoxifies Microplastics and Plastic Byproducts in One Week (Rhonda Patrick's Plan)Added:
I want to talk plastics for just a moment though because we mentioned earlier about uh BPA and excreting it through the urine. First off, what is the difference between like a microplastic and like you know plastic toxins like cuz we there's there's a difference and do we have any ways to potentially expedite the clearance of either one of those. So microlastics are the break they're the the product of the breakdown of larger plastic. And so this happens with two factors. One over time oxidation heat. Anything that increases oxidation breaks down the the plastic. And these microlastics range in size you know from five micrometers down to like the nanometer size. Right? So there's the microlastics and the nanoplastics. And the smaller they get, the more dangerous they get because they can go across membranes easier. But, you know, you can have something that's a microplastic that's the size of, you know, a piece of rice. That's a microplastic or down to like the size smaller than the size of a grade of sand. Smaller to things that you can't even see, right? So, micropl that would be a microlastic.
the the plastic associated chemicals are the chemicals that are put into the plastic to make them more durable, to make them more flexible, to give them all the properties that they need. And those include a lot of the the common ones that we've heard of like bisphenol AA, BPA, or the replacement. When you see something that's BPA free, it usually has something in it called BPS.
>> We now know BPS is just as bad as BPA, perhaps even worse. So, when you hear the word BPA free, it's 100% marketing, brilliant marketing. People think it's like safe. it's not. It has other chemicals. Phalates being another one.
Phalates are a big problem um particularly during development. They play a role in >> in in um eurogenital disorders. So like it it's terrible. Women that are exposed to a lot of phalates during pregnancy have boys that have hypospadia. So their urethal slit is like further back. So a lot of times they'll have to sit on the toilet to pee because they don't have the right stream. Um undescended testicles is another big one for phalate exposure during pregnancy and these things are very common. I mean like like 20% of boys nowadays have undescended testicle and this is affecting fertility. It affects testicular cancer risk. It affects cancer risk in general.
Phalates affect cancer risk in general.
So the point is is that these plastic associated chemicals are problematic. So are the microplastics. These things are accumulating in our heart in our brain.
They're associated with Alzheimer's disease, cardiovascular disease. they cause inflammation much like that visceral fat and it's a chronic inflammatory signal that's happening right so our body our body processy processes these these types of toxins differently so people want to know how do I detox some microplastic right first of all we're being explos exposed to these plastic chemicals like constantly like everywhere like like even if you're doing everything that you can you're getting them in your body like it's just it's impossible to avoid it's impossible now you can reduce your exposure exposure. That's the best thing to do.
But if you have been exposed, people want to know, well, can I detox of microplastics?
And I would tell you that right now there's no really good safe way that's known to do that. the best the your best bet is because microlastics and nanoplastics when you when you consume them through water or food. Uh if you have if you're consuming if you're consuming them through water, you're going to want to eat it with food after you hear what I what I'm about to say because microplastics are excreted through feces. That's the way you get rid of microplastics. They don't come out your urine. You're not sweating out microplastics. They come out feces. And so the way to get rid of microplastics is to not absorb them essentially. So if you're consuming them, you want them to go straight out your feces, right? And and that that does happen except for the fact that it depends on the size of the microplastic. So the smaller the size of the microplastic, it really can cross the membranes of your epithelial cells lining your gut very easy. And that's where fiber comes into play. Fiber is your best bet against microplastics right now because of two reasons.
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>> First and foremost, if you have insoluble fiber, right? That's the stuff that is moving food through you quicker.
Vegetables are a great source of in insoluble fiber. That is going to move the microplastics. It's going to not allow them to have the time to be absorbed. So, it moves it through faster. You will poop out more microplastics with more more insoluble fiber. The soluble fiber or the fermentable fiber as it's now called.
This is the kind of fiber that is found in a lot of fruits or it's found in like artichokes or onions, inulin. It's found in betaglucans and mushrooms and oats, right? Like th this type of fiber that's fermented. It's that beneficial prebiotic that we hear about. It's the stuff that our good bacteria like to consume and and ferment and it makes more of the good bacteria. Well, the other thing that it does is it causes this is why it used to be called soluble fiber. It's kind of now called fermentable fiber. The reason it's called soluble fiber is because it makes this viscous coating in the gut. And that becomes very important in understanding nanoplastics because it coats the microplastics and nanoplastics and kind of prevents them from being able to get across the gut membrane. So you will move it through your feces rather than absorb it through your gut epithelial cells. So you want to get a combination of both soluble and insoluble fiber to basically poop out the plastic essentially. That's that's what you want to do. And right now that's your best bet. better than any other stuff you're going to hear online.
That's that is the best way that you're going to quote unquote excrete microplastics. You're going to excrete them through your poop.
>> That's exactly what I've said, too.
Yeah. I know there's a little bit of a what is it? Bile acid segregation, right? So, it's like a little bit of soluble fiber with possibly some fat, right? Yes. So, that's that's basically eat some I mean, I would say like chia flax seed, right? Something like that. I mean, again, you could go down the uh phytoestrogen rabbit hole with flax, but the point is like you've got a little bit of fat, a little bit of soluble fiber, you know, you've got a perfect little mix right there, >> right? Um, and that and that kind of dubtales into the chemicals because, you know, some of these plastic associated chemicals are also excreted differently.
So, the BPA, the BPS, the phalates, those are those are being excreted through urine. And the way to increase that excretion is you want to activate the enzymes that cause BPA to become soluble. BPA is not soluble. It's not water soluble. It has to get converted in the body to a water soluble metabolite and that's how it's excreted.
And the enzymes that do that are activated by my favorite compound found in broccoli and broccoli sprouts, sulfurophane. So the enzymes that activate um you know that basically make BPA water soluble are the same ones that make for example benzene w water soluble. Benzene is something that we breathe in through air pollution through wildfires, smoking cigarettes, right?
And there's me now at least three different human studies showing that people that consume sulfurophane in the form of its precursor glucaraphin and then you know are exposed to benzene they excrete 60% more benzene after 24 hours and that's because you're basically activating that pathway nrf2 pathway through the sulfurophane sulfurane is the the biggest natural product activator the biggest dietary activator of that system, the detox system is sulfurophane. So, I take sulfurophane every day. I take a product called um Avacol, which is the reason I do Avacol is because it's been shown in 12 different clinical studies to be effective and um they have a really a really good product and I'm not associated with them or affiliated with them. I just happen to like stuff that's evidence-based. So um I do that every day and that is essentially to get rid of these plastic associated chemicals like BPA and the phalates. Now you mentioned bile acids that's interesting because that would that would kind of bring us into the forever chemical category. So, forever chemicals, those are, you know, these are the these are the chemicals, they're called forever chemicals because unlike BPA, which has a half life in our body of a couple of hours. We're just constantly exposed to it constantly. So, so that halfife is like 2 and 1/2 hours or something like that. And then if you take the sulfurophane, you're going to you're going to basically cut that in half. So, you're going to basically get rid of it faster.
The forever chemicals stay in our body for years up to like five years and it's really they they stick around and they are also very damaging. Right. So that the way that those chemicals are excreted are through bile acids and and actually there's some some animal evidence out there showing that the beta glucans in like oats or mushrooms >> can excrete the forever chemical clearance through bile acids.
>> Interesting.
>> So that's kind of interesting that you were kind of mentioning that pathway as well. But it's important to keep in mind, you know, there's there's all these plastic compounds and chemicals and microplastics that we're exposed to.
And yes, you should try to, you know, reduce your exposure to them by getting a reverse osmosis water filter to filter because they're in our water, you know, by try not to eat packaged foods.
They're all in our any anything with packaged foods, it they shed into our food. We're eating them. You know, you there's lots of like avoid putting hot beverages into plastic. So like to go beverage cups are lined with plastic.
You're getting, you know, orders of magnitude more microplastics. You're drinking plastic coffee is what you're doing when you go to Starbucks and get those like disposable cups because they're lined with plastic. So that that's a that's a you know, do what you can to reduce your exposure, but you're not going to completely reduce it. I mean, it's just literally everywhere in all of our food. It's in our meat. All meat is being packaged in plastic. Even if you're a hunter, you gota you're gonna put your stuff in the freezer.
What are you going to do? You're going to vacuum seal it in plastic. It's everywhere. So, you want to try to do what you can to mitigate your exposure to it, but you also want to try to detox from it. And I think the best ways to do that, like I said, fiber for the microplastics, both both soluble and insoluble fiber, sulfurophane, so whether it's broccoli sprouts or you take a supplement like I do to get rid of the plastic chemicals like BPA, BPS, and then making sure that you're getting those again soluble fiber, fermentable fiber from betalucans like the mushrooms and the oats to help with the forever chemicals.
>> Does it matter if mushrooms, they don't have to be raw or anything, right? You could saute them or >> you can saute them. Yeah. With the broccoli, there's a there's a way to get more sulfurane out of it, right?
>> Yeah. Yeah. So, broccoli sprouts have about a hundred times more of the precursor to sulfurophane glucaraphin than mature broccoli. And I'm just calling it sulfurane because it's easier for people to grasp that concept. But mature broccoli, if you want to get more of that, you know, glucaraphin out of it, you can and and conversion into sulforophane, what you do is you add mustard seed powder to it because mustard seed powder has an enzyme that converts the graphin into sulfurophane. And so you're going to get like up to four-fold more. There's a study, human study, showing that people that added mustard seed powder to their broccoli increased the bioavailability by four-fold. So that's a trick that I remember to add back because I used to do it religiously. Now I supplement with this. So I figure I get I get it all from my supplement. But um that's a little hack to do as
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