Biotherapeutics - Protein sciences and Structural biology

[00:00:00]hello my name is Shankar I'm the team lead for protein science student photography at apsl we offer a comprehensive suit of activities from sequence optimization to final product generation in gene to protein services our team has experience in handling difficult and complex Target molecules we offer services and solutions with the flexibility of multiple entry points to help our clients we are proficient with the most modern Exposition platforms and our facilities are equipped to handle scale ranging from milligram to grams protein Expressions scale up using spinner flask Shake flask hyperflask and wave bioreactor platforms to handle volumes up to 50 liter scale with low operating costs our protein expression platforms include bacterial insect mammalian these combination of high-end instruments and a wealth of scientific expertise we provide optimized purification platforms for research and Drug Discovery needs we are proficient in purifying a tagged as well as untagged and all classes of Target proteins from mammalian Eastern microbial expression systems performing a number of routine protein analysis throughout project stages ensuring the identity Purity structural and conformational integrity stability and function of the protein our protein crystallography service provides a One-Stop solution for determining 3D structures of proteins protein to protein complexes protein small molecule complexes antibody antigen complexes at high resolution protein crystallography projects are typically carried out in gene to structure format encompassing gene cloning protein expression purification crystallization screening synchrotron x-ray diffraction structure solution and refinement our structural biology expertise also includes protein engineering to enhance the sliceability of a difficult Target protein we seamlessly integrate structural biology with drug Discovery programs thank you thank you