Retatrutide is a potent GLP-1 receptor agonist that uniquely combines GLP-1, GIP, and glucagon receptor agonism, making it particularly effective for appetite suppression and fat mobilization during caloric deficit. Unlike other GLP-1 agonists, its glucagon receptor activation promotes fatty acid mobilization from adipose tissue, enhancing fat loss beyond appetite suppression alone. While it may cause temporary flatness during cutting phases due to reduced carbohydrate intake, this can be managed through proper electrolyte balance and dietary manipulation. Retatrutide shows promise for managing food addiction and improving insulin sensitivity, though addiction symptoms may recur upon discontinuation. The medication is typically dosed at 0.25-0.5mg three times weekly for maintenance or higher doses during cutting phases.
Deep Dive
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Deep Dive
This One Medication Completely Destroys Food Addiction And Burns Fat At The Same TimeAdded:
Uh certainly for food addiction, it's probably hands down one of the best medications you could take. Albeit that the addiction, the food addiction or other kinds of addiction might come back with a ventions when you take retroutite out.
Anecdotally, Retroutite is the most potent and most productive GLP-1 receptor agonist out there when it comes to appetite management and fat loss.
Overall again you get this added benefit of glucose dependent insulinotropic receptor agonism or glucagon receptor agonism which might actually help with fat mobilization especially if you do this during caloric deficit and you really control your diet regarding dietary fat intake. So you have less less fatty acids going into atapost tissue and more fatty acids coming out of adapost tissue resulting in net fat loss assuming that your caloric expenditure is sustained for the entire time that you're using retroite in a caloric deficit. So most people have already pivoted from exotite, lurlutide, semiglutide and even tzepidite. Even though there's still a lot of people that favor tepidite over retroite because they feel they get better appetite suppression from tepidite on a milligram for milligram basis compared to retroite. But tepidite is a good amount cheaper approximately 30% cheaper than retroutite comparing all the sources which sell tepidite and retroite. So the guys that notice um improved appetite suppression with tepidite over retriutite they stay with their zeppite because the price is lower and thus it's more cost effective. Now during the offse it seems that retriite might offer some benefits regarding the sustainability of insulin sensitivity and the prevention of non-alcoholic fatty liver disease. But I think that the benefits regarding insulin sensitivity and the benefits regarding non-alcoholic fatty liver disease are stemming from caloric restriction being stimulated by the satiation and the appetite blunting effect of retroite.
Still, if during the offseason you tend to overeat, which is what I do, I eat more than I need to um to make progress regarding the cruel of new muscle tissue, strength sides, etc. Um I tend to overeat a little bit so I get fat during the offseason. So the next time I do an offseason, I will definitely include ritutes at let's say 0.25 milligrams three times per week at the maximum half a milligram three times per week to see if this insulin sensitizing effect remains. Uh I'll of course I will check um you know my liver health with a fibro scan and ultrasound regarding non-alcoholic fatty liver disease which I resolved years ago. It hasn't come back yet luckily. So I'll keep track of that before and after. Um, but there might be something to say for it. Albeit that in the scientific evidence, it's not very conclusive regarding this uh potential benefit, but anecdotally in the bodybuilding community, there are a lot of guys who blunt their appetite or at least take away the food noise so they don't overeat during the offse and they report that they have better glucose homeostasis or don't need to use insulin at all while they use retroid at a low effective dose of let's say 0.25 milligs to 0.5 milligs three times weekly. It's very hard to determine if this potential beneficial effect regarding insulin sensitivity during the offseason results in the acrual of more muscle tissue, increasing strength sides, and overall muscularity. Um, that remains to be debated, but again, there's plenty of anecdotal reports of people showing a before and after including retroite in their polyarm pharmacy protocol with anabolic energy, steroids, growth hormone, and whatnot.
And they look better than their previous offseason. So, it's worth looking into.
I'll definitely look into it myself during the next off seasonason when I'm done with this cutting phase and I get my lower back fat and the glute fat under control. I'll add in the retro tight and then see how much of a difference it makes and then maybe report back to you guys with an addendum live stream. But to be fair, I've also heard reports of people claiming that retutite or tepid for that matter makes them flat, which is to be expected to a certain extent because it blunts your appetite. So it restricts your carbohydrates and fat intake uh unless you really forcefeed uh through the appetite suppression obviously and the people claim that datite might cause flatness through this glucagon receptor activation. Now if you activate the glucagon receptor on the liver obviously you get a gluconogenesis and glycogenolyis modulating your blood glucose levels and dumping a little bit of this glycogen stored within the liver into the bloodstream. But it doesn't work like that on the skeletal muscle. Right? once glycogen is stored in skeletal muscle it's in it's locked in there you literally need to burn that away through activity. So if you take retroat during the cutting phase and your carbohydrate intake is restricted then obviously you're going to be a little bit flatter than you would otherwise during an offseason where you can eat a bload of carbs and your glycogen stores in skeletal muscle are saturated to the max to the point you now have full-blown insulin resistance. Right? This is how it works. So if you have good insulin sensitivity, all of the carbohydrates would go into skeletal muscle, which is something that retroite promotes obviously. So you should not go flat. If you go flat, it's a problem with your electrolytes. It's a problem with your overall caloric intake or your carbohydrate intake. And through some intelligent diet manipulations, you should be able to restore the flatness to somewhat fullness and still get a solid pump in the gym. And otherwise, guys, otherwise that's what the Anadrol is there for. I made an entire video about how to get skin splitting pumps, whether that's during the offseason or a cutting phase, whether you're on retroite or not. So, give that one a watch. Regarding fat loss though, it's absolutely amazing, right? Not only do you get appetite suppression, you also get this mobilization of fatty acids, which is unlike the other GLP1 receptor agonists because this one also contains uh GIP and glucagon receptor agonism.
But until this bioblutide hits the market, I think that retroite is probably your best appetite suppression compound over the other stimulatory fat burners that raise your heart rate to the nth degree. Right? An elevated heart rate of what was it? 6.7 to 12 beats per minute. I think it's acceptable during a cutting phase and you should be able to mitigate that by doing daily fasted cardio which is something you should do anyway. So regarding uh appetite management and fat loss, I think rotutite is next level compared to the other GLP1 receptor agonists. But once bioglutide hits the market where you get quadruple agonism also of the IGF-1 receptor, I think we're all going to pivot from retroutite to bolutite. But stay tuned for that deep dive that might drop a couple years from now because scientific evidence right now paper thin and it's not available anywhere. And regarding addiction and dopamine signaling whether that's food addiction, drug addiction or other kinds of addictions, gambling addiction, porn addiction, there are some antidol response that retroite or gelp1 receptor agonists help with the resolvement of these particular addictions. So it's something worth looking into. Will it be as potent as cerebralin or ible gain treatments for example? Probably not.
But as long as you're using retroite or another GLP-1 receptor agonist, it might be easier to manage these symptoms of addiction and preventing addiction from recurring. Obviously, uh certainly for food addiction, it's probably hands down one of the best medications you could take. Albeit that the addiction, the food addiction or other kinds of addiction might come back with a ventions when you take retroutite out.
I've experienced this myself when taking tracepite out or llutite out in the past. food addiction comes back and I'm morbidly well not morbidly obese but I I gain fat like nothing else because well the appetite is so ravenous and I can't undereat in that or physically I can't undereat in that particular context so yeah it's it's pretty tough I think when I start rectite again I'm going to keep it at a low and effective dose and maybe a little bit higher dose during the cutting phase just to take away the food noise and prevent a rebound and again the clinical trials regarding appetite suppression and the management of obesity they ramp up the dose of retroite. Keep that at a certain point.
Let's say up to 12 milligs weekly for over a year and then they taper it downwards but keep the retroite in to sustain this appetite suppression and keep obesity management or type type 2 diabetes management under control because they know when they take it out based on the other clinical trials and scientific evidence on GLP1 receptor agonist that that's probably not a good idea to do. So it only works while you're using it. And if you suffer from an addiction and use retrojutate to overcome this addiction, then you're probably on retroite for life, albeit that you should be able to lower the dose quite significantly, at least in the context of food addiction. All right, I'll leave it here. Please let me know your anecdotal response and reports to retroat. Did you get side effects?
Did you get beneficial effects? How did you find it stacking with other GLP1 receptor agonist or other appetite suppressions, whether those are stimulatory or not? And how was your fat loss journey, your cutting phase by adding retroite in? Was it significantly easier or did you just feel that you were spending a boatload of money?
Because again, retroite ain't cheap and that's why we have discount codes out there. All right. If you start self experimentation, you should do your blood work over at Merrick Health. If you live in the United States, they have excellent healthcare providers and patient care coordinators who can help you interpret your blood work results and make sure that you stay healthy while you're undergoing self experimentation with Polyarm pharmacy.
And if you can't figure it out by doing blood work at Meric Health, then you can always contact me for a consultation and I'll gladly sort out your protocol with you together on a consultation call. You can find all of my other sponsors and affiliates down below in the YouTube description section. And if you can't find a particular sponsor or affiliate there, head over to my website, the vigorsteiff.com where everything is explained into great detail. Vigorous crew, you guys know what to do. Almost on Richard to tight frontal biser for you guys. Not quite on Richard yet, otherwise I'll be a lot leaner. Um, but hey, maybe at one point or another my appetite becomes unmanageable and I need some appetite suppression. And then the first thing that I'll I'll look into is retrogut at a low effective dose. sulfa half a milligram to 1 millig subcutaneous three times weekly.
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