Mitochondrial transplantation is an emerging medical technique that involves transferring healthy mitochondria to damaged or diseased cells to restore cellular energy production and combat various chronic diseases. Research has shown that mitochondria are essential for immune function, and their dysfunction contributes to conditions like long COVID, Alzheimer's, Parkinson's, and cancer. While this technology was originally developed for heart surgery in infants about 10 years ago, it is now being explored for emergency applications including heart attacks, strokes, wound healing, and burns. The body naturally increases mitochondrial production during infections, but this is limited; transplantation allows for therapeutic supplementation. Major institutions like Northwell Health are actively researching this approach, representing a potential revolution in medicine that addresses the widespread issue of mitochondrial dysfunction in chronic diseases.
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Mitochondrial Transplantation Explained and What Has Already Been DoneAdded:
If I hadn't done the amount of reading on mitochondrial dysfunction and these kind of things before I reached out to you, I don't know if I could even believe this. It's so It's so um Well, it's hopeful and futuristic and it sounds too good to be true until you start linking all these weird chronic diseases and being like, well, why are there so many people so many people who are sick with like multi-system failure? It's not just their brain, it's not just mental illness, it's chronic fatigue, it's pain. Like, what hits the whole body and why are there so many kind of untreatable disorders like people talk about chronic chronic COVID like long COVID is a big thing. Lyme disease like >> COVID destroys mitochondria. It is a proven fact. They've studied the papers came out two two years ago. COVID destroys mitochondria on a massive basis.
So, it just hit some people like some people got hit harder and ended up with long COVID and they don't know what to do with it.
>> there's many other things. The thing about mitochondrial dysfunction is it's kind of like it's always there in the background, but it may it may not be the main reason.
But, it's a contributing factor for so many things, okay? If your energy levels go down, what happens when we hit 55, 6 years old? People start getting Alzheimer's, they start getting Parkinson's, they get ALS, they get arthritis, they get, you know, all these diseases, right?
If they get can- or and cancer, of course, your odds of getting cancer at 60 are like 10 times more than when you're 30 because your mitochondria have got weak and they can't power the immune system anymore to keep the keep the all the cancer under control. There's also other things that cause cancer that have nothing to do with the mitochondria, but it's like it's like a car that's all beat up that's running out of fuel. Well, it's beat up, it doesn't work very well, and it's running out of fuel.
You know, right? You You could fix all those things. So, that's the thing about mitochondria is they're they may not be the main reason, but they're always a contributing factor in all these diseases, okay?
And what you're saying, what you're getting to is that we as a society are not dealing with this at all.
There's no doctors anywhere, and I talk to doctors every day.
And they're like, we had no idea.
The scientists have no idea. This is not in the textbooks. This is really that new.
Uh where, you know, mitochondria as a part of the health care system is just non-existent.
Yeah, that's It's a revolution, and I believe I believe it is a coming revolution in medicine.
So. Uh yeah, I so do I. Um are there any doctors using this that you know of? Like in any way?
Yeah, I mean, we we're So, that the people who discovered mitochondria transplantation, that was about 10 years ago. They've been using it in human patients in a very, very small scale. You like it This This was originally used for heart surgery on on babies. The guy who invented this did it because he wanted to restore some of the damaged tissue in the heart when he was operating on these children.
And so it's it wasn't just In that case, it wasn't chronic disease. He was doing it to fix an injury, okay?
There are Northwell Health, which is one of the which is the actually the biggest hospital chain in New York state. It's a 23-hospital chain.
Their whole system is working on this.
They've got projects going to look at how to use this in the emergency room.
Really? People have heart attacks.
If you have a heart attack, give you a big jolt of a fresh mitochondria that get into the heart and you could bring back a bunch of that tissue. There's been studies on stroke victims.
Very successful. They've used it for skin back wound healing. There's people using it for burns. There's people using it for for chronic diabetes wounds.
Um You know, >> Okay. smear it on. You smear it on a wound on the outside of the body and put a band-aid over it and the mitochondria are in the or in the the gel that you put on there and they get into the tissue and they and they Whoa. Yeah. It's like that that uh uh Remember uh uh The Hunger Games, you know, they had a she had this little jar of cream and she put it on and it made the wound magically disappear. It's science fiction kind of stuff, okay?
>> [clears throat] >> The biggest problem is that when people hear all this, they they think, "Oh my god, this is, you know, you guys are crackpots."
Yeah, I mean that I mean yes, obviously that's what it sounds like, but if you actually like read the studies and think about it, it does make sense.
Like it does make sense.
It's just I guess it in nature you wouldn't have this huge influx of mitochondria. So, it's science fiction as in like the body can produce it with stem cells and you can slowly heal, but you wouldn't ever have a paste with a huge dose of mitochondria to heal things. Well, actually, when you get sick, if you get an infection or if you get cancer, the number of mitochondria that are put loaded into each platelet doubles.
That's been proven. And so, the body is responding.
Oh, okay.
>> more mitochondria when they're needed to fight an infection.
And then people always say, "Well, why doesn't it just keep sending that number all the time?" Because it's rationed.
Because it has a limited quantity. See?
So, the body is constantly trying to adjust. Like, it doesn't want to use them up too fast, but it also needs to keep you alive.
So.
>> That makes sense. Really interesting.
So, what we can do then as doctors is say, "Okay, well, we can we can we can take them from the outside world." So, what I was saying was that the idea of mitochondrial transplantation and what all these all of all of these researchers are researchers are testing is that we can take mitochondria from potentially from donors or more likely we grow them in a in a bioreactor, which is what we're focused on primarily. And then you can have your bioreactor growing a new mitochondria for you. And if you get sick, you can you can get a big a big chunk of them.
And even if you're elderly, you know, that you could basically make your immune system much stronger until you get rid of whatever that illness is. So, or if you're in the hospital, they could have bags of transplantable mitochondria. And if somebody comes in who's been, you know, a soldier or a firefighter or somebody who's who's been badly injured, they could give them in the mitochondria to help them heal faster.
>> [music]
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