Mitochondria in muscle cells play a crucial role in glucose uptake from the bloodstream, and when mitochondrial function is impaired, glucose metabolism becomes disrupted; research shows that compounds like urolithin A can restore proper glucose transporter function in muscle cells, potentially improving metabolic health.
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This Cellular Chain Fixes Glucose UptakeAdded:
Is it fair to say most of your mitochondria in your body lives in your muscle?
>> I would say in your muscle and probably the brain.
>> So the more you use your muscle, the more of your mitochondria are able to remove that glucose from your bloodstream, protecting your metabolic >> You nailed it. One of our collaborators did exactly this study where they actually looked at obese people who don't respond to many of the current medications and they found problems in in this glucose transporter chain in the muscle and when they put cultured them with urolithin A, they can suddenly get better glucose uptake.
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