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Monophasic Liquid Dosage Form | Pharmaceutics | GPAT 2027 | Class - 10 #gpat2027 #gpatexam
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136 views8likes6:40pharmacyindia4182Original Release: 2026-05-29

In monophasic liquid dosage forms, solubility classification according to USP standards defines 'soluble' as requiring 10-30 parts of solvent per part of solute, while 'freely soluble' requires 30-100 parts. During syrup preparation, excess heat causes inversion (hydrolysis of sucrose into glucose and fructose), leading to increased viscosity, fermentation susceptibility, color darkening, and reduced sweetness.

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