β-Caryophyllene for Parkinson’s: Protecting Dopamine & Easing Symptoms

Beta-caryophyllene (BCP), a plant-derived compound found in black pepper, rosemary, and hops, offers neuroprotective benefits for Parkinson's disease by interacting with the endocannabinoid system in the brain's basal ganglia, specifically protecting dopamine-producing neurons through reduced dopamine activation and release, decreased oxidative stress, and induction of cellular autophagy; BCP provides symptom relief for pain, restless legs, muscle hesitation, depression, anxiety, and sleep issues while being non-controlled and having no impairing side effects, though caution is needed with SSRIs due to potential serotonin syndrome.