L-38 - NIPER JEE 2026 | Pharmacology: Drugs Acting on Central Nervous System | 360 Series #niper

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[00:00:00]Hey dear students, let's start, son, as we discussed today, in the next class we will study about the CNS i.e. Central Nervous System, please confirm with me whether you have revised CNS [nasal sound], that's good, you have revised it. Let's start with the first question from CNS for all of you, Intacapone and Tolcapone are both types of enzyme inhibitors. There is no point in just giving answers. I have given this answer.

[00:00:46]But I want you that if this question comes, you should remember the entire classification of Parkinson's drug once, that sir, here our drug works in the dopamine system or works in the acetylcholine system. Now if you talk about the dopamine system, then dopamine precursors come here. Like libidopa is talked about. Dopamine facilitators come in. Where amantadine is talked about.

[00:01:16]Dopamine agonists come in. Where bromocriptine pergolide dropicinol pramipexole come in. Then here comes Mao B Inbiter. Where we talk about who? Let's talk about Selejan Raslan.

[00:01:30]Next come the COMT inhibitors.

[00:01:33]Where entecapone tolcapone is talked about.

[00:01:36]And then there are the acetylcholine antagonists.

[00:01:39]Where we talk about whom sir? Let's talk about the By Benz Pro.

[00:01:44]Do you remember these things? You should remember me, children. Then you have missed one more good thing Sir, here comes another class which we call DDC inhibitor. In other words, dopa decarboxylase inhibitors, one of the major drugs, will be carbidopa and benzoyl peroxide.

[00:02:02]So sir, these will also be our drugs.

[00:02:04]Remember how tough it is. If you take a look at all the classes, you will get to know which drug of our class is from where and how it works.

[00:02:14]All things will come. Now if you remember Levodopa, you should also remember the on-off phenomenon. Now if Carvidopa is remembered then its synergistic action with Levodopa should be remembered. When you recall all the things in your mind and keep them running in your mind, then you become a perfect student. Chlorpromazine medication can decrease the level of dust in the brain. Now you all know what chlorochromazine is, kids? It is a dopamine antagonist. Isn't it?

[00:02:41]Because what does this mean to us, sir? It is a typical antipsychotic agent. And what does typical antipsychotic agent mean?

[00:02:50]Ok? What does typical antipsychotic agent mean? The reason is that they agonize our main dopamine system. They are called typical A typical agonists.

[00:03:02]Now here we will talk only about dopamine. Serotonin will not come, right? Both A & B don't make any sense.

[00:03:09]Well, which class of drug is it?

[00:03:11]Chloropromazine is a phenothiazine class of antipsychotic drugs in the typical antipsychotic class.

[00:03:16]Where we first talk about Where we first talk about which of our drugs comes in? So let's talk about dopamine.

[00:03:25]Yes, we were talking, Sir, what are we missing here? Chlorochromezine Phenothiazine derivatives which fall into three classes.

[00:03:31]First of all let us talk sir, ours is aphthatic side chain containing than piperidine side chain containing than ours is which one sir? Phenazine side chain containing or we talk about here drugs may also be missing them. Thioridazine comes from our piperidine. Chlorpromazine Triflomazine comes in aliphatic and if we talk about chlorphenazine then it comes in that.

[00:03:55]Apart from that comes butyrophenone, which is a class of drug that is similar to haloperidol. Further, there we also had a trick for this, Pheno, so what about others, that is, Thioxanthin derivative, where you will remember our drug Blufenthikol. Okay, we will talk about Pimo and we will remember him here too. Then you will remember all these drugs. Ok?

[00:04:15]Apart from that, if you also see that Sir Chlorpromazine has our maximum alpha blocking property. It has dopamine receptor blocking properties.

[00:04:25]Due to which its adverse effect is also seen in other systems. Ok? Now, these are typical things.

[00:04:33]If we talk about A typical, what will come to mind?

[00:04:37]Cutie Rose Closau will be missed. Clozapine will be discussed. We will talk about Qutiapin, sir, think a little, which of the following barbiturates is not ultrafast acting, what is our HMT, sir, Thiopentol, Methhexetol or Hexobarbitol, this comes in ultra short acting, but sir, Phenobarbitol Pheno, so we are talking about Pheno, that means the battery of my phone should be long, so sir, this is Phenobarbitone, so it comes in long acting, how it comes under the ultrafast acting, sir, it will not come in ultra because in ultra you talk about HMT, that means Thiopentone, Methhexetone, Hexobitol is talked about. In short comes Butopento and in long comes our Phenobarbitone Mephobarbitone.

[00:05:25]It comes under the classification of barbeque.

[00:05:28]When talking about sedatives and hypnotics. When it comes to Benzodiazepine, we have seen separately that it is a sedative hypnotic, anti-convergent and anti-anxiety. It also relaxes skeletal muscles. Diazepam is our only drug that works through the skeletal muscle relaxant CNS.

[00:05:46]Underneath comes the centrally acting muscle relaxant.

[00:05:49]Benzodiazepine is a drug of the same name which is used in the treatment of somnolence.

[00:05:56]Other reviews include Methonin, Remelan, and the receptor agonist Suren.

[00:06:03]All these things should be remembered, right? Let's go to the next question. Alcohol reduced to aldehyde.

[00:06:10]Alcohol reduced to aldehyde in the presence of alcohol, now aldehyde is formed from it.

[00:06:16]Acid is formed from aldehyde. Now when aldehyde is formed from alcohol, it is required for aldehyde dehydrogenase. Sorry alcohol dehydrogenase. And when acid is formed from aldehyde, then our aldehyde dehydrogenase is involved there. And here it is worth remembering that our drug Fomepizole inhibits the alcohol dehydrogenase enzyme.

[00:06:40]Whereas our disulfiram class drugs inhibit aldehyde dehydrogenase. So here the correct answer will be D answer i.e. alcohol dehydrogenase. This is the enzyme that inhabits us, who is it, sir?

[00:06:57]Conversion of alcohol to aldehyde. Now whether you take ethyl alcohol or methyl alcohol. If it is methyl alcohol then formaldehyde. If ethyl alcohol then acetaldehyde and from acetaldehyde acetic acid. Formic acid from formaldehyde.

[00:07:13]If even two drops of formic acid are taken, meaning even 1 ml, it will become very toxic and will cause retinal damage.

[00:07:26]We neuroleptics are used to treat neuroleptic neurosis psychosis narcolepsy Parkinson's disease neurosis psychosis Sir, will you talk about psychosis?

[00:07:44]Neuroleptics means the story of the game of our neuro transmitters.

[00:07:52]Neurooptics will be discussed.

[00:07:56]Where does psychosis occur?

[00:07:58]Distortion of thought and perception is talked about.

[00:08:00]This is all psychological.

[00:08:03]Antipsychotic drugs, these are what we call neuroleptics or major tranquilizers, please listen to me carefully. Whether it is called neuroleptics, drug for treatment of psychosis or major tranquilizer. Well, if a minor tranquilizer comes, remember that we are talking about the anti-depressant class.

[00:08:24]Minor depression will be discussed in major psychosis.

[00:08:28]Neuroleptic psychosis will be discussed.

[00:08:31]Which of the following is not an anesthetic? You will tell this to everyone.

[00:08:46]Not an anesthetic. Iodoform is not an anesthetic, sir. Iodoform is not an anesthetic.

[00:08:53]You have read the rest.

[00:08:56]Nitrous oxide volatile liquid was mentioned in the gas. Step aside. I had read this.

[00:09:01]Temo comes in fast acting. Then we talk about inducing. When it comes to slow acting, Benzodiazepine MDL comes into play here.

[00:09:08]Dissociative anesthesia involves ketamine, which is an NMDA receptor agonist.

[00:09:15]Fentanyl and remifentanil are also used as opioid analgesics.

[00:09:19]What is all this about us? General anesthetic agents are administered. Now there is a story about all this.

[00:09:24]Like you know where propofol is used? Sir, our day care uses propofol for surgery. 1% We might have talked about it. Also, if we talk about our ketamine, it is a dissociative anesthesia. Where our memory loses things for some time.

[00:09:40]That is called dissociative anesthesia. If we talk here, let's talk about ether, halothane and gases.

[00:09:48]So here we come to know what is our ether? It is inflammable. Gas is not our inflammable.

[00:09:55]But this point comes that sir, its potency is less. And if we talk about the potency of all the drugs mentioned here. Sir, which one is the most potent here and which one is the least potent? Please confirm it to me quickly.

[00:10:13]Precursor of dopamine. Precursor of dopamine. Look, we saw a classification of Parkinson's in the beginning. We will get all these drugs from there. We don't need to do anything different.

[00:10:34]Let's go for peripheral dopa decarboxylase inhibitor.

[00:10:39]Peripheral dopa decarboxylase inhibitor. Sir, any dopa decarboxylase inhibitor will work only peripherally and will not work centrally, whether we talk about carbidopa or benserazide, why both of them are peripheral, sir, because if it goes centrally and after going centrally it inhibits the dopa decarboxylase enzyme, then the conversion of levodopa to dopamine will not be possible, then what will be the use, now see, this has happened for us here, there is no story of clozapine in COMT, selegiline mao has also become an inhibitor, so there is no other doubt, so yes, our correct answer here is that we have to remember that all our dopatic carboxylases, that is, there are only two of them, both of them work peripherally. They Do Not Can Cross the Triple B They Just Act as the Bodyguard to Help the Levodopa to Cross the Triple B Easily. That's all I do.

[00:11:40]Protects from peripherals. Which of these is used as the pre-anesthetic medication?

[00:11:45]Let me tell you which of these drugs is used in pre-anesthetic medication? We will talk about aspirin, atropine, amlodipine or astaxanthin. Well, you should remember atropine because you know atropine is an anti-cholinergic drug, what does it do? Decreases the flood.

[00:12:03]Now if salivation decreases, lacrimation decreases, urination decreases, defecation decreases then surgery becomes easier. The action of anesthesia improves. So but it's not just atropine. We've looked at a lot of classes of drugs. Like atropine has been talked about due to its antisecretory action. Also here we talk about hipotropium bromide sorry home atropine and cyclopentolate.

[00:12:27]For mydriatic and cycloplegic action.

[00:12:29]Ipratropium bromide, tiotropium bromide in asthma will be discussed.

[00:12:33]Sir, this is our Cimetidine, see, if basically it will be asked which is our anti-cholinergic drug which has the maximum and the best useful pre- anesthetic medication, then one thing must be remembered that Sir, as we have discussed here, our Atropine and along with it comes our Cyclopentolate, which is not written separately. Well, that class of pre-anesthetic medication is not given in it but you can add it separately. Ok? Promethazine is used by us. Please listen carefully. Promethazine is used.

[00:13:06]Used with antipsychotics.

[00:13:08]Atropine and glycopyrrotate are used as anticholinergics. H2 blockers are used. PPIs are used.

[00:13:16]5 ST3 agonists are used. All of these are used separately for different roles in our as a pre-anesthetic medication.

[00:13:24]Morphine poisoning is reversed by. Let us go.

[00:13:31]Okay, will you give me the answer to reverse morphine poisoning Nalgine? If the question comes that can morphine dependence be controlled by morphine dependence, tell me quickly, can morphine dependence be controlled by, then we will remember, yes GD, please give the answer, let's move ahead now, I hope you will give me the answer in the comment, we will talk about non negen, this is our knowledge. Hey methadone D for don what did we say? It's Don. D for Don Mithe Don. This is used as the antidote to morphine to control dependence Nelogan has read many times. Indicate the anesthetic which is used intravenously.

[00:14:21]Now which one is intravenous?

[00:14:23]Sir, this is gas. Leave it. Sir, if we talk about it, both of these are volatile liquids. Get on the A side. This is our inducing agent.

[00:14:32]Yes, it is used intravenously.

[00:14:35]So the correct answer will be A. Propofol will be missed by Temo. We will remember from Tem Temo Sir, the matter of propofol will come. Which of the following agent is an opioid agonist.

[00:14:49]Opioid antagonists. It's the same story again. Will the answer here be amorphine?

[00:15:08]Opioid agonist is asked. Morphine itself is an opioid. So how can opd be an agonist? Naltrogesen G Eftamine Dope Test remember different. Disulfiram, its story is different. So let's talk about Neltrogzen.

[00:15:25]Nelogene, Nylarogene both are comes under the opioid agonist. Opioid pure agonists are also called. Isn't it?

[00:15:33]Because in this we have seen different classes.

[00:15:35]First comes our remedy mu receptor agonists where we talk about natural, semi-synthetic and synthetic.

[00:15:41]When it comes to natural, all these drugs come to mind like morphine, codeine, thebaine, nocipin, papaven.

[00:15:47]Now you might be missing these things even more. There is something else said about Pepwen. Can you tell me what it is called? If you talk about semi-synthetic opioids, then heroin, pholcodine, ethyl morphine all come under it. In synthetic, all these drugs like Pathen, Methadone, Tramadol, Fentanyl are seen here.

[00:16:05]Ok? Apart from that when we talk about agonists and antagonists. So we said a small line, pants but mine.

[00:16:13]That means sir, here comes pentazocine, butorphanol, there is nalorfin, there is nalbuphin. These are agonists and antagonists. That means they have the agonistic action on the mu receptor and the agonistic action on the kappa receptor.

[00:16:33]Okay then we will talk about partial antagonist plus agonist.

[00:16:38]Now here Ibuprofen Norphine is the only drug which is a partial agonist and a kappa antagonist. Pure antagonists include our Nalgin, Nitrogen and Nalafen.

[00:16:51]These are drugs of different classes but they are definitely asked for in different types.

[00:16:56]I had asked you a question that Sir, this paperine of ours is a liquid.

[00:17:03]Alkaloid is something that comes in liquid alkaloid.

[00:17:06]Which of the following analgesic is a phenanthrene derivative. Now we had remembered this simply. If you want to remember phenanthrene, remember MCT and remember benzo isocyanine then remember NP. That means simply morphine, codeine, thebaine.

[00:17:22]Morphine, Codeine, Thebaine, Papiven. While vein while noscapin and papeven what is our?

[00:17:28]Benzo isoquinoline derivative.

[00:17:31]We talk about phenanthlene derivatives and benzo isocunene derivatives on the basis of their structure. The highest concentration is seen of this morphine only.

[00:17:40]Hypnotic drugs are used to treat hypnotic drugs Sir obviously I am not able to sleep. If there is a sleep disorder then we will use hypnotic agents because sedatives and hypnotics are the agents which reduce the anxiety, induce the cool and calm situation and relax.

[00:18:02]While what do hypnotics do? Induces sleep.

[00:18:07]Hypnotics Vi of the following is Dissociative Anesthesia No time waste give direct answer move ahead Thiopentol Barbiturate Fentanyl OPD Dazepam Benzodiazepine The story is different for all of them They work in different places through different mechanisms They work in different ways Ketamine Dissociative Anesthesia NMDA receptor agonist Highly lipid soluble drug Can rapidly cross the triple B Used for the operation of the head and neck. These are dangerous for the hypertensive stomatic heart disease because they have the adverse effect on the heart. Dissociative anesthesia is not given in heart situations. Dazapam is used as a major tranquilizer and a minor tranquilizer. We just talked about it or medium tranquilizer. Please confirm it to me. The Major has been talked about. It's psychosis. Minor tranquilizers, that is, depression, we are talking about anxiety. If we talk about medium tranquilizer then ours will come. So do we use diazepam for depression? Will you talk about the minor?

[00:19:15]Minor tranquilizer, anxiety. Hey, it's okay if I'm not depressed. It is used in anxiety. I know a little bit. Talk about muscles and massagers. There is no word like medium. It is either major or minor. Don't bring it to the medium.

[00:19:39]What is the question, there is something to understand in this, son. Now as I told you earlier.

[00:19:43]What are major tranquilizers?

[00:19:48]Antipsychotic drugs are called major tranquilizers which are used in schizophrenic and other situations. Can you tell me if Diazepam is used in psychosis? No sir, it is not used. So where is it used sir?

[00:20:01]We see its use. It is used in anxiety.

[00:20:03]Used in selective hypnotics.

[00:20:07]Used for muscle relaxation. Now sir, if it is being used for anxiety then what do we call it? Minor trunklizer. Because there is depression and anxiety.

[00:20:17]All this is because of this. Epilepsy is a different matter. Epilepsy has no role here.

[00:20:23]Anticonvulsant drug working via the inhibition of T gated calcium channels.

[00:20:29]Sir, this is a sodium channel blocker. This is also a sodium channel blocker. It works on our GABA.

[00:20:35]Now the answer is written in front of you Sir Ethosuximide. Yes, which is our calcium channel blocker. It is most commonly used in absence seizures.

[00:20:47]It is also approved for myoclonic seizures.

[00:20:49]But if the drug of choice comes, we will first look at valproic acid and then try to move on to ethosuximide.

[00:20:57]Ropinol is used in the treatment of seizure anxiety. Parkinson's disease Bromocriptine Pergolide Ropinol Pramipexole is a dopamine agonist. Where will it be used? Will be used in parking.

[00:21:10]This is what we saw from their classification. These are the dopamine agonists running through the story.

[00:21:14]Anti-epileptic drug Carbamazepine Acts As Now we talked about what is Carbamazepine? Belongs to the sodium channel blocker class of drugs. So the sodium channel blocker that is the carbamazepine. What are good sodium channel blockers? So we have phenytoin, phosphenytoin, carbamazepine. What is this Mainly ours? Sodium Lamotrigine is our main sodium channel blocker, so mainly you have to look at these three, Phenytoin, Carbamazepine, Lamotrigine, which are kept in the category of sodium channel blockers, under the Epilepsy, let us look at the classification of anti-epileptic drugs.

[00:21:55]Select a drug which is having five to one A receptor agonistic activity.

[00:22:03]5 ST 1 A receptor agonistic activity one A, there is no confusion son, look Buspirone 5 ST 1 andasetron 53 cyproheptadine antiserotonin and antihistaminic will be discussed, where will clozapine come in, sir, our antipsychotic will come in atypical, so what is the answer, Buspirone will be discussed, Buspirone, yes that is the drug of the Buspirone class, which is our lazy receptor, it is not an auto receptor, so our Buspirone works on 5 ST 1 A and inhibits the release of the neurotransmitter that is called serotonin, it inhibits its release.

[00:22:55]No brother, for the suggestion of nicotine, I repeatedly say that there is a difference between Buspirone and Bupron.

[00:23:00]Bupron is used.

[00:23:04]Buspirone is not used in smoking cessation. Do n't make me break my head.

[00:23:10]Which one of the following drugs is agonist of the dopamine.

[00:23:15]Agonist of dopamine. Please tell me the side effects of TCA drug in the following.

[00:23:43]Yes, what does TCA do? Weight gain, hypertension, CNS stimulation. Are you joking sir? What is a better answer than weight gain? It causes weight gain. TCA will be discussed.

[00:23:54]TCA would be any class of drug.

[00:23:57]All this has an adverse effect. Increased appetite and weight gain may precipitate the conversion. But yes, weight gain is our first priority.

[00:24:04]Which of the following congeners of morphine produces the highest dependence?

[00:24:09]Which of the following causes the highest dependence? Odin Theamine Papaverine Apomorphine and Diacetylmorphine i.e. Heroin Diacetylmorphine Heroin Highest dependence is seen.

[00:24:34]Benzodiazepine toxicity can be reduced by the use of What antidote is given for the toxicity of benzodiazepine?

[00:24:44]Flumagen is used. Obviously, we have a specific antidote for it. And it is not just used for benzodiazepines.

[00:24:54]If you are asked about the antidote for non-benzodiazepine, remember this also.

[00:24:57]Antagonist of benzodiazepine.

[00:25:02]Why again brother? Why again?

[00:25:05]Overdose of Pentazocine Is Treated by Now Look What was Pentazocine? We said that we got to see both agonist and antagonist here. Now if there is both agonist and antagonist then what will be given?

[00:25:18]Pure antagonist will be given.

[00:25:21]Which is the pure antagonist? Nelogzen and Nelogzen will be seen. So here we are getting the direct answer of nailon only.

[00:25:30]Always remember this thing whether it is a pure agonist or an agonist and agonist or a partial agonist. The antagonist of all these will be a pure agonist. What we have is Negzen and Nelgzen. There is no specific antidote for barbiturates. That's where the urine is made alkaline. That's all that is kept. Parkinson's disease is characterized by a deficiency of dopamine. Deficiency has been asked. If it had been asked to increase concentration here, I would have given acetylcholine. Or if you just asked about deficiency then we will go with dopamine.

[00:26:11]Parkinsonism treatment therapy with levodopa is usually combined with carbidopa. Please give me the role of a bodyguard. Why are you taking so much tension? Increase penetration through the blood brain Decrease dopamine metabolism in the CNS Decrease dopamine metabolism in the peripheral Well increase the stability of levodopa Does it have any role Sir, to prevent metabolization of levodopa into dopamine in the peripheral What is given for this, dopa decarboxylase inhibitor whose name is Carbdopa and then Sirajid which of the following drug is aldehyde dehydrogenase inhibitor aldehyde dehydrogenase inhibitor Desulfiram We saw in front of us the drug use in the treatment of bipolar disorder Will you talk about lithium, will you talk about bipolar disorder or here we talk about ours, if we talk as a mood stabilizer then only lithium will come up Paralysis as intensity is the synonyms of Parkinson's disease, Alzheimer's disease, dementia Jacob's disease, you must have heard a lot about it. Hey friend, he got paralysis. He got paralyzed.

[00:27:25]Why did paralysis occur?

[00:27:29]Baahubali series for Sniper will start on YouTube.

[00:27:33]From June 8 at 9:00 am. Starting on June 8th at 9:00 AM. Will end on 8 9 10 11.

[00:27:49]Let's next look at the condition in which Parkinson's disease occurs: hallucinations, and it is difficult to distinguish between dream and reality. This condition is non-age when they cannot find any difference between dream and reality, then what will it be called?

[00:28:14]Psychic neurotropic neuroleptic or mania is hallucination sir, one minute it is hallucination, let's not go much further, hallucination is psychological, isn't it?

[00:28:35]Wherever hallucination is discussed, hallucinogens are called psychics, these are the psychoactive substances, powerful alter the perception, where there is no significant difference between dream and reality.

[00:28:53]Seroquel works as Seroquel works as non-epinephrine agonist beta receptor agonist gava agonist or 5T2A receptor agonist Seroquel some children will say sir I have heard it for the first time, no this is not the first time, okay if I have heard the name Seroquel quetiapine have I heard the name quetiapine? Hey, it 's a brand name, you fool. It is the brand name of Quetiapin. Have you heard of Quitia Pin? I haven't heard of Serol because I asked for that brand name. Does Pam Fast acting, general anesthetic, slow acting, inducing local anesthetic.

[00:29:42]Where will the local come from?

[00:29:44]So slow and fast. Now give the answer in this.

[00:29:46]Well, now see how it went wrong.

[00:29:50]You will apply a little logic.

[00:29:53]what is written?

[00:29:57]Seroquel.

[00:30:01]Sero means Sero means serotonin.

[00:30:10]Sero means serotonin. What was there to say next? There was no need to even think about it. Sir, Dazy Pam slow acting general anesthetic, okay, fast acting has come, okay, good, from where did fast acting come, son, in fast acting, there is Temo, Dazypam, benzodiazepine, when it comes to slower acting drugs, there is a difference between short acting and slower acting, short acting and slower acting are different, the one you are talking about Tom is short acting, here we are talking about slower acting.

[00:30:48]Respiratory depression is caused by respiratory depression and constipation, a basic thing that will be seen with all our above derivatives.

[00:30:59]We will remember morphine severe due to which we get sir yes miosis analgesia or respiratory depression physical psychological dependence will be talked about. Then here we will talk about histamine release, itching, nausea, vomiting, euphoria, constipation, cough suppression and vagus stimulation, seration and hypnotics. This morphine CBS is very useful. Biculan acts as the agonist of GABA A receptor.

[00:31:25]What is Bikulan? We will talk about agonists of GABA A receptor.

[00:31:28]Chlorpromazine is an agonist sir, it comes under dopamine agonist, main one is our D2 agonist, so there is no need to go into other receptors.

[00:31:40]Haloperidol is a strong antipsychotic and weak sedative. Strong antipsychotic is a weak and strong sedative. Haloperidol is a butaphenone derivative. Please tell me sir, we are talking about butaphenone. It has strong active and weak sedative strong antipsychotic and weak sedative action. Haloperidol is also widely used in Giles syndrome.

[00:32:10]Penfloridol is its longest acting.

[00:32:13]That is why it is said that weak action is found in it. Which category of drug is used in the attention deficit hyperkinetic disorder?

[00:32:24]What is the use of ADHD in ADHD, sir?

[00:32:26]Psychostimulants are like attention deficit, there are some people like oh friend sir did not pay any attention to me, he did not listen to me, so what happens to him because of that, he gets depressed or becomes hyperactive, so our psychostimulants are used in attention deficit hyperkinetic disorder, we will talk about ADSD which of the following is a degenerative disorder, degenerative disorder Parkinson Alzheimer according to you it will be Parkinson. Wo n't you get Alzheimer's? It is understandable that myasthenia gravis does not occur.

[00:33:07]Alzheimer's is also neurodegenerative.

[00:33:12]Both will be ours here.

[00:33:17]Exactly.

[00:33:19]What is the gap now? He did not mention it here. Why is the answer given?

[00:33:26]One of our diseases is Alzheimer's, which is an example of a classical neurodegenerative disease. Where the brain shrinks, memory loss occurs, cognitive function loss occurs. And that's where Parkinson's, our progressive Parkinson's, a progressive neurogenerative disorder. But both are neurogenerative.

[00:33:46]Libodopa is essential in Parkinson's treatment because it can cross the biological membranes. Yes sir. Triple B sorry not biological Triple B can cross the membrane. High affinity of morphine acts on V-OPD receptor. If morphine is discussed then mu receptor will be discussed first.

[00:34:05]That's where all our other work starts.

[00:34:07]Mu receptor shows the antipyretic action analgesic action.

[00:34:12]Analgesic action will be seen.

[00:34:16]You will get very good analgesic and supra analgesic action. Let's talk about the mu receptor.

[00:34:22]All of the following are antiepileptic drugs which act via blockage of sodium channel except sodium channel sodium channel but Viga Batrin to kisi angle se nahi hoga sir because it is a GABA transaminase inhibitor it works on GABA which of the following is a depressant is a selective serotonin reuptake inhibitor selective serotonin reuptake inhibitor Floatin Flomin Sertraline Celopram Celopram what are all these for us?

[00:34:52]SSR I Selective Serotonin Rheooptic Inhibitor will be discussed.

[00:35:00]What is good Phenalgin? Non-selective MOI inhibitor. What is desipramine? It is a TCA class drug. And let's see periprazole is a drug which class. Where are you sir? Antipsychotic. And among antipsychotics, what is an atypical antipsychotic class of drug.

[00:35:23]Antiepileptic drugs used in pregnancy. Now if we talk about pregnancy, then what did we say sir?

[00:35:28]Remember Lemotayajin Levotsam. Let's take Carbomazepine in the end but never take any other drug.

[00:35:38]What is our phenothiazine antipsychotic?

[00:35:41]Thioridazine, yes it comes in this, trifluperidol butaphenone thioxanthine flupenthixazole zotiapine sir it is our atypical class drug so if we talk about phenothiazine antipsychotic then thioridazine or we can say that in our phenothiazine three sub classes aphtic piperidine and pipeine have been talked about which one of the following is anti depressant anti depressant will be talked about is stron. By the way, the name is wrong here.

[00:36:13]Must be Granny Cetron. So it would have been better if Granny Cetron had come.

[00:36:21]Apitriptan Trazadone The answer here was Trazadone.

[00:36:27]Trazadone drug safe in pregnancy. Now look, the question has been changed a little bit here. Now here but with whom will we go? Will go with Labtracetam. Because what are we getting first? Levtracetam is getting us first. So we said, remember Levetiracetam sequence wise.

[00:36:49]Talk about Levetiracetam, Lemotrigine, and Carbamazepine. Epilepsy during pregnancy will be discussed. So here are our today's 50 questions from the whole CNS which was our target to revise.

[00:37:01]If you people have studied and worked hard, then I think that after seeing the questions, you would have felt good that yes, some questions are good and at the same time, you would have also understood where the mistake is happening and you would have caught that too. Ok? So revise well. Let's thank you