Classroom | Candid Shoeplay #127

Added: 2026-05-07

[00:00:00]to that sentence >> right now. Plug some of those in transcription translation and then >> you must use each of those words in your response.

[00:00:15]>> All four So that works. Now what I want you to do is tell me more specifically being So start off with the mutation changes the protein because >> the mutation affects the DNA gene code or the DNA sequence. Very good.

[00:01:31]the DNA sequence is the first step in the process of >> right now from protein synthesis we go from DNA to what >> RNA very good >> how that information is transcribed into RNA right now Then RNA is translated into protein because of that shift in the original DNA sequence. We now have different amino acids, right? Which create different proteins, right? So it changes the nature of that protein, okay? Which can change the structure and the function simultaneously, right? So on this example here up at the front, >> okay, >> I have a normal sequence, right? that are a normal sequencing. Okay, I have a strand of DNA, I have my strand of RNA, and then I have my protein. Okay, I see here in pairs of three, right?

[00:02:36]Excuse me.

[00:02:37]I'm transcribing DNA into RNA, right?

[00:02:41]So, G A T into CUa into glucine, right?

[00:02:46]Which is a specific amino acid, right?

[00:02:48]We don't have to worry about those right now. Uh but again I have these four amino acids right coming from DNA which is transcribed into RNA and then RNA which is translated into these amino acids. Okay on the opposite end I have another sequence or another synthesis right but we're having a frame shift mutation occur. Okay so one of these particular bases is being taken out. So this G here is being removed. Okay. That guanine is being removed from that strand. So these first two amino acids right when they are transcribed and translated from DNA and RNA to protein okay I still have leucine and the next amino acid correct and even in this particular instance I still have the same amino acid okay but just be different types of codons right different organizations of these three letters uh that can code for different amino acids right but here at the end we see that this particular sequence is now being read differently than this one and that's what's changing right this specific amino acid in this particular example is what's being changed okay so that deleted base changes the amino acid sequence which changes therefore the overall resulting protein or the structure the function or the nature of that protein in many instances >> okay >> is the URL >> huh >> the U and RNA is that uricil Yes. So you and RNA is yours. So uh what I want you all to do right now is read this aloud to me as a class. As a class, I want you all to read this definition aloud to me.

[00:04:31]>> So I would like to see everybody reading. Okay. On the count of three.

[00:04:36]One, two, three.

[00:04:41]>> Daqu okay. Hold on. Hold on. Hold on. All together. All together. Make sure you're all reading this together simultaneously.

[00:04:51]On the count of three again, I want to hear it all in sequence. Quiet. Quiet.

[00:04:57]Ready. One 2 3.

[00:05:13]>> Okay. Still a little off. also was reading at the speed of light. Okay. So, a mutation changes the protein because it changes the DNA sequence which changes the mRNA during transcription and then during translation different amino acids are added which leads to a different protein. Okay, we've been talking about this for a few weeks now.

[00:05:35]But again, as we move into evolution, all right, as we move into this new unit, we're going to want to really be able to focus in on mutations, why they're occurring, okay? How they occur, and how they're affecting the process of evolution when we get into micro and macro uh types of evolution. Okay? So, what I want you to do right now is pull out your Chromebooks. We have a small quiz on this topic of mutation. All right? We're going to go ahead and we are going to reanalyze.