Frontotemporal Dementia (FTD) is a progressive neurodegenerative disease affecting the frontal and temporal lobes of the brain, typically occurring between ages 40-65. The most common behavioral variant causes dramatic personality changes, loss of inhibitions, apathy, and lack of empathy. The disease results from abnormal accumulation of misfolded proteins (tau and TDP-43) that damage neurons, with 30-50% of cases having a genetic basis, particularly the C9orf72 mutation. The cerebrum, comprising 85% of brain weight, is divided into four lobes: frontal lobes (decision-making, planning, personality), parietal lobes (sensory processing), occipital lobes (visual processing), and temporal lobes (auditory processing, language, memory). FTD specifically damages the frontal and temporal lobes, leading to the characteristic behavioral and cognitive changes.
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I warned you that Barrow is experiencing frontotemporal disorder/dementia (F.T.D.), yet you do......
Added:July 2026.
[snorts] President President Then I speech.
years.
I believe that is suffering from frontal temporal disorder, frontal temporal dementia, FTD.
And uh I was hoping that uh the Gambian will take it seriously but unfortunately they don't take it seriously and 2 years after I decided and I hope and I pray they will take it seriously.
This is what I believe co he is suffering from frontto temporal disorder or frontal temporal dementia.
In front temporal dementia is a group of progressive neurogenerative disease brain frontal and temporal losses damage temporal disorder or frontal temporal dementia between 40 and 65 is between 40 and 65 years.
It lead drastically personality behavior change.
If you have frontal temporal disorder, the most common type behavioral sometimes because everything I do is in Dutch, because temporal disorder temporal deically personality behaviors and language change and the most common type the behavioral varants you lost or you have no inhibitions apathy and lack of empathy.
So inhibition inhibition what is inhibition psychological restraint if you don't have inhibition for example normal circumstances.
But if you don't have inhibitions that because that prevent people from acting freely inhibition but [cough] excuse me but if you don't have inhibition then you act freely you expressing inner emotions. the way you want without thinking or without careing about the effect people. You don't care about that anymore because you don't have inhibitions.
You don't care because you don't have inhibitions.
Psychological and social context.
Psychological and social context.
Then in a social you don't have inhibition.
You don't have inhibition. So also that means you do things freely.
You think freely.
You said things freely. You do things freely without a shame or any shame of How are they going to feel in the society?
No.
He wouldn't care anything.
How are they going to feel? No. Oh, how would opposition going to react?
You don't care about that because you don't have any in inhibitions and you wouldn't care about How are they going to feel social life?
He wouldn't care about that. Just to give one example, I could remember there was a time at my work similar to with a lot of doctors and nurses within the country.
So from a different part of the country.
[clears throat] So bring when we are having coffee break.
So I came from Gambia.
So how can you people vote someone in office?
But straight away we are living in a modern world of technology anything language I put in the internet. So no no because and up to now he never came out and regret. He never came out and apologize Gambians.
because social and psychological context I don't have any inhibition behavioral the frontal temporal disorder or fronttoal temporal dementia psychological and for example also For example, normal circumstances.
Don't get me wrong.
No, no, no. Don't get me wrong.
is he or she is suffering from frontal temporal disorder, frontal temporal dementia because of behavior.
He don't have he or she don't have any inhibitions psychological and social context.
You go to the second one that is apathy.
Apathy.
Apathy. What do you mean by apathy?
Well, it is lack of feelings, lack of emotions, lack of interest or concern.
If you are having frontal temporal disorder or frontal temporal demia you then you go to apathy you have l of feelings you don't care about anything you don't feel or you how people are going to feel about what you are going to say you don't care how other people whether you will hurt them what you are going to say. You don't care about hurting others.
As long as you say what you want to say, where you want to say, when you want to say, and how you wanted to say it, you don't care about it.
And within this, there are how to call it key aspects of apathy. In key aspect of number one, emotional blunting.
Emotional blunting is one of the key aspect of apathy.
Emotional blunting.
Well, it reduce the ability to feel or express positive and negative emotion.
Positive and negative emotion.
It reduce the ability to feel or to express emotional uh positive and negative emotional.
So now your ability to feel and express I will reduce. So at that moment you wouldn't care whether the emotion is positive or negative or whether he or she or they are going to feel more positive or negative or whatever. No no no no no emotion whe it doesn't concern you. You do it the way you wanted to do it. You say it the way you wanted to say it. You act the way you wanted to act about it.
Because you you don't care about people because people you don't care about that because of the apathy and the key aspect of that apathy that is uh how to call emotional blunting and that emotional blunting that reduce the ability to feel express and positive to feel is to reduce ability to feel or express positive and negative emotions. I call it apathy. The emotional blunting of the apathy. And another [laughter] aspect of apathy, it is lack of motivations.
Lack of motivation.
You have many many part of it.
How to call it? It reduce your desire to engage in the goal.
You concentrate, you put your energy on different things than your goal.
just uh he went to inaugurate his 9-point agenda but a ninepoint agenda the reason of the gathering the main reason of the gathering is in inauguration of the nine-point agenda but instead of okay [laughter] that nine-point agenda is the goal of that meeting of that gathering the main goal of that gathering is uh the nine point agenda so that nine-point agenda, instead of concentrating on that nine-point agenda, [laughter] instead of telling the Gambians what are his plans or how to go or do or how to establish that 9, what he is going to do, how is he going to implement all those instead of saying that to the G, telling that to the Gambian people, instead of explaining deeply to the Gambian people about his 9 agenda, his put against the turn because about this is why totally left because of the frontal temporal disorder, frontal temporal demensia, the frontal and temporal behavior.
this lack of emotion.
The next [snorts] key aspect of apathy influence.
The another key aspect of apathy that is influence influence not caring about social, psychological and personal events.
completely.
But instead of Instead of CJ people, instead of no that is the influence, not caring.
about social, psychological and personal uh how to call it events because >> [laughter] >> They don't need it. They follow.
So we go to number three that is lack of empathy.
Lack of empathy is part of behavioral variant. Lack of empathy of empathy.
Inability or unwillingness to understand, share or validate another person's emotions.
Inability or or unwillingness to understand, share or validate another person's emotion.
You don't care about it.
lack of empathy because you don't have any empathy. So if you don't have empathy, you wouldn't care about also deep effect interpersonal relationship.
Lack of empathy, it also deeply affect [laughter] interpersonal relationship. Because of lack of empathy, you don't care about other people's feeling. For example, 2021 presidential campaign We have to say it because according to him.
But why This empathy also this also deeply affected interpersonal relationship. ship relationship.
Likewise between and interpersonal relationship because of why? Lack of empathy without thinking without considering the emotions of other people's because And that causes the deep effects of personal uh relationship between citizens.
Temporal disorder fold from Jamaru because uh neurons in the frontal and temporal brain will damage leading to strength.
damage leading to shrink.
So new frontal theory.
Yeah. because uh how do you call this the generation okay it driving the abnormal accumulation of misfold proteins there are misfold proteins abnormal misfold proteins like u for example like protein like tow and TDP 43 tow and TDP 43 New misformed abnormal accumulation misfort proteins and those misfold proteins to and TDB43 up to 50% of up to 50% cases genital or genetic based and run in the family. So temporal disord misformed or misfolded proteins no one number two about genital or genetic basis.
So, the cellular and protein abnormalities because new frontal temporal disorder or frontal temporal dementia microscope there are specific abnormal proteins abnormal accumulate new accumulator inside the nerve cellulate.
So they interfere the normal cells eventually it causes the neurons to die.
It causes the neurons to die.
The causes of frontal temporal disorder it caused by the progressive damage and death of neurons. So true microscopic level there are specific abnormal proteins inside normal cells function interfere neurons.
So that's an example protein about 30% of frontal temporal disolar cases.
30% of them how to call it protein and TDP43 protein meaning the most common pathology mayo is about 60% of cases involve the abnormal build up so% of the cases abnormally built within the nervous cell w uh a protein is called TDP43.
So new protein for protein and TDP 43 proteins accumulate they are abnormal proteins accumulate interfereal function interfere neurons.
You got to temporal disorder or frontal temporal dementia goal.
The genetic mutations genetic mutations about 30 [snorts] to 50% of all frontal temporal disorder about 30 to 50% of all frontal temporal disorder case are directly responsible for inherited form of the disease.
30 to 50% of all frontal temporal discord.
C90 RF72 C90 RF72 is the most common genetic mutation.
It links to frontal temporal dementia.
C9 RF72 also can cause ALS but it is one of the it is the not one of but it's the most genetic mutations.
It links to fronttoal temporal dementia or pronto frontal temporal disorder. And the second motation is mapped mapping mapped.
It affect the protein. The protein just a few minutes ago. The pro among the two proteins the tow protein this mapped mutation protein effect and the third one is GRN program GRN program another type of mutation potential regulation Affect it change and affect the regulation of the proteins.
That two abnormal proteins accumulate in the nerves.
After interfering neurons suffering from frontal temporal disorder or frontal temporal dementia you come to cerebrum.
Cerebrum is the largest and upper most section of brain.
nervous system.
Nervous system responsibility is responsible for conscious thought, intelligence, memory, emotion and processing the sensory informations and motor functions.
is the largest and upper section of the brain and ner thought intelligence memory emotions and processing of sensual information and motor function.
It contain 85% [music] it contain about 85% of brain total weight 85% of it roughly that 85% of the weight cerebrum contain that system command center and it is the largest and upper section of the brain.
So where almost roughly 85% of brain total weight but it is divided into two primary regions divided into two primary regions each regions different control mechanism method.
So two dives are the left and right hemisphere. I divide all into two. The left and the right uh hemisphere.
The left hemisphere side. The left side.
Yeah. It control the right side of the body and also excels the logic and the language.
The left hemisphere of the brain.
The left side that control the right side of the body.
and also exert the logic and language the right side control the left side of the body special and creative task is divided into two hemisphere and also into four main loes.
He divided into four men's loves four men loves that is love P that P sorry FP O T sorry FP FP F mean frontal loes P mean paral loes O mean occipital loves T mean temporal loes in four main loes. No frontal loes frontal loss manage decision making planning personality and voluntary muscles movement.
So thinking, decision making, planning and your personality [snorts] temporal disorder.
It leading to drastic changes in personality, behavior and language.
drastically changes personality, behavior and frontal temporal disord Because frontal temporal dementia because the frontal lo and temporal loto temporal frontal lo temporal lo together frontal temporal disord so because there are four main loves in the cerebrum. So but the main concern about these two making plant personality and voluntary muscles movement but still second one processing sensory information regarding touch pain and temperature and oipators that decided entirely to interpreting visual informations like shape, color and recognition but I don't want to go detail in it because and second temporal loss in temporal loss that handles auditory processing language comprehension and memories.
So these two losses frontal temporal disorder in frontal and temporal loss combined together disord frontal temporal dementia in course behavior.
And the last one another also memory temporal loy memory.
Tomorrow we'll come to the same place to the same people talking to the same people about the same issue in a different way different way.
No, sometimes I sometimes he is suffering from frontal temporal dementia.
Sometimes Different people completely in front emotion.
not only about other people.
This is why so much unnecessarily It has made people.
But because of he is suffering from frontal temporal demensia instead I'll put note on it.
No, no, no.
Don't Yeah.
$500,000.
Out of that 500,000 150,000 a day.
At least these are the things he is suffering from frontal temporal disorder.
He or she don't care about because it's not good for his health.
But he don't realize it because the frontal and temporal loss of his brain is damaging.
So this is why.
So I hope and I pray doctors advisor they look into it.
Maybe I'm wrong.
I believe I believe I personally I believe that he's suffering from temporal disorder. Could be possible.
It's possible.
is definitely suffering from frontal temporal disorder or frontal temporal dementia.
for
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