GLYCINE FATES MNEMONIC #glycine #biochemistry #medicalmnemonics

Added: 2026-05-04

[00:00:00]Pneumonic to remember fates of glycine is proteins can help produce good conjugated neurotransmitters. P for proteins. Glycine is the smallest amino acid and appears at every third position collagen allowing tight packing of the triple helix and giving strength to skin, bones and connective tissues. C for creatine. Glycine combines with arginine and methionine to form creatine, which is stored as creatine phosphate and provides rapid energy during muscle contraction. H for heme.

[00:00:29]Glycine combines with succinyl CoA in first step of heme synthesis leading to formation of hemoglobin, which carries oxygen in red blood cells. P for purines. The entire glycine molecule becomes part of purine ring contributing to DNA and RNA synthesis and supporting cell division. G for glutathione.

[00:00:46]Glycine joins glutamate and cysteine to form glutathione, a major antioxidant that protects cells, especially red blood cells, from oxidative damage. C for conjugation. Glycine helps detoxify harmful substances by forming compounds like hippuric acid and also combines with bile acids to form bile salts needed for the fat digestion. Glycine acts as inhibitory neurotransmitter in the spinal cord and brainstem by opening chloride channels, reducing nerve activity and stabilizing signals.