Statins Reduce Major Cardiovascular Events By 30% In Primary Prvention

[00:00:00]So in case you see that in the future, you'll know what it means. So that's today's topic. Statins reduce major adverse cardiovascular events by approximately 28 to 30% in relative risk for primary prevention. In other words, preventing the first one of anything. So in absolute terms, statins prevent approximately 1.3 MACE per 100 persons treated over 1 to 6 years with the benefits increasing um over time to 2.5 MACE prevented per 100 persons at 5 years. Now, what are the specific primary prevention benefits? And I think you'll be impressed. So the most comprehensive evidence comes from meta-analysis of multiple randomized controlled trials in adults without prior cardiovascular disease. In other words, they've had nothing. So statins versus placebo demonstrated a reduction in composite cardiovascular outcomes of 28